KAT2A (NM_021078) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207889L2V

Lenti ORF particles, KAT2A (mGFP-tagged)-Human K(lysine) acetyltransferase 2A (KAT2A), 200ul, >10^7 TU/mL

Product Images

RC207889L2 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC207889L2V particle to overexpress human KAT2A-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: KAT2A
• Synonyms: GCN5; GCN5L2; hGCN5; PCAF-b
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_021078
• ORF Size: 2511 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207889).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021078.1
• RefSeq Size: 3074 bp
• RefSeq ORF: 2514 bp
• Locus ID: 2648
• UniProt ID: Q92830
• Cytogenetics: 17q21.2
• Protein Families: Transcription Factors
• Protein Pathways: Notch signaling pathway
• MW: 93.7 kDa
• Gene Summary: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]