RDH5 (NM_002905) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205138L2V

Lenti ORF particles, RDH5 (mGFP-tagged) - Human retinol dehydrogenase 5 (11-cis/9-cis) (RDH5), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: RDH5
• Synonyms: 9cRDH; HSD17B9; RDH1; SDR9C5
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_002905
• ORF Size: 954 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205138).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002905.2
• RefSeq Size: 1354 bp
• RefSeq ORF: 957 bp
• Locus ID: 5959
• UniProt ID: Q92781
• Cytogenetics: 12q13.2
• Protein Families: Druggable Genome
• Protein Pathways: Retinol metabolism
• MW: 34.9 kDa
• Gene Summary: This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]