TMEM27 (CLTRN) (NM_020665) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204775L4V

Lenti ORF particles, TMEM27 (mGFP-tagged) - Human transmembrane protein 27 (TMEM27), 200ul, >10^7 TU/mL

Product Images

RC204775L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC204775L4V particle to overexpress human CLTRN-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CLTRN
• Synonyms: NX-17; NX17; TMEM27
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_020665
• ORF Size: 666 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204775).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020665.2
• RefSeq Size: 1580 bp
• RefSeq ORF: 669 bp
• Locus ID: 57393
• UniProt ID: Q9HBJ8
• Cytogenetics: Xp22.2
• Protein Families: Transmembrane
• MW: 25.2 kDa
• Gene Summary: This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]