MMAB (NM_052845) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC204290L3V
- LentiORF®
Lenti ORF particles, MMAB (Myc-DDK tagged) - Human methylmalonic aciduria (cobalamin deficiency) cblB type (MMAB), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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USD 365.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | MMAB |
Synonyms | ATR; cblB; CFAP23; cob |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_052845 |
ORF Size | 750 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204290).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_052845.3 |
RefSeq Size | 4154 bp |
RefSeq ORF | 753 bp |
Locus ID | 326625 |
UniProt ID | Q96EY8 |
Cytogenetics | 12q24.11 |
Domains | DUF80 |
Protein Pathways | Metabolic pathways, Porphyrin and chlorophyll metabolism |
MW | 27.4 kDa |
Gene Summary | This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found. [provided by RefSeq, Apr 2011] |
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