POLG2 (NM_007215) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203462L2V

Lenti ORF particles, POLG2 (mGFP-tagged) - Human polymerase (DNA directed), gamma 2, accessory subunit (POLG2), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: POLG2
• Synonyms: HP55; MTDPS16; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_007215
• ORF Size: 1455 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203462).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007215.2
• RefSeq Size: 1607 bp
• RefSeq ORF: 1458 bp
• Locus ID: 11232
• UniProt ID: Q9UHN1
• Cytogenetics: 17q23.3
• Domains: HGTP_anticodon
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Metabolic pathways
• MW: 54.9 kDa
• Gene Summary: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]