Artemis (DCLRE1C) (NM_022487) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203407L2V

Lenti ORF particles, DCLRE1C (mGFP-tagged) - Human DNA cross-link repair 1C (DCLRE1C), transcript variant b, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Artemis
• Synonyms: A-SCID; DCLREC1C; RS-SCID; SCIDA; SNM1C
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_022487
• ORF Size: 1731 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203407).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022487.2
• RefSeq Size: 6242 bp
• RefSeq ORF: 1734 bp
• Locus ID: 64421
• UniProt ID: Q96SD1
• Cytogenetics: 10p13
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Non-homologous end-joining, Primary immunodeficiency
• MW: 65.3 kDa
• Gene Summary: This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]