PPP1R3C (NM_005398) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203153L4V

Lenti ORF particles, PPP1R3C (mGFP-tagged) - Human protein phosphatase 1, regulatory (inhibitor) subunit 3C (PPP1R3C), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PPP1R3C
• Synonyms: PPP1R5; PTG
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005398
• ORF Size: 951 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203153).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005398.3
• RefSeq Size: 2576 bp
• RefSeq ORF: 954 bp
• Locus ID: 5507
• UniProt ID: Q9UQK1
• Cytogenetics: 10q23.32
• Domains: CBM_21
• Protein Families: Druggable Genome
• Protein Pathways: Insulin signaling pathway
• MW: 36.4 kDa
• Gene Summary: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016]