CIRBP (NM_001280) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201639L2V

Lenti ORF particles, CIRBP (mGFP-tagged) - Human cold inducible RNA binding protein (CIRBP), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CIRBP
• Synonyms: CIRP
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001280
• ORF Size: 516 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201639).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001280.1, NP_001271.1
• RefSeq Size: 1397 bp
• RefSeq ORF: 519 bp
• Locus ID: 1153
• UniProt ID: Q14011
• Cytogenetics: 19p13.3
• Domains: RRM, RRM_1
• MW: 18.6 kDa
• Gene Summary: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.[UniProtKB/Swiss-Prot Function]