UROD (NM_000374) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200529L4V

Lenti ORF particles, UROD (mGFP-tagged) - Human uroporphyrinogen decarboxylase (UROD), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: UROD
• Synonyms: PCT; UPD
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_000374
• ORF Size: 1101 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200529).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000374.3
• RefSeq Size: 1408 bp
• RefSeq ORF: 1104 bp
• Locus ID: 7389
• UniProt ID: P06132
• Cytogenetics: 1p34.1
• Domains: URO-D
• Protein Families: Druggable Genome
• Protein Pathways: Porphyrin and chlorophyll metabolism
• MW: 40.8 kDa
• Gene Summary: This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.[provided by RefSeq, Aug 2010]