DARS (DARS1) (NM_001349) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200391L2V

Lenti ORF particles, DARS (mGFP-tagged) - Human aspartyl-tRNA synthetase (DARS), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: DARS1
• Synonyms: aspRS; DARS; HBSL
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001349
• ORF Size: 1503 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200391).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001349.2
• RefSeq Size: 2322 bp
• RefSeq ORF: 1506 bp
• Locus ID: 1615
• UniProt ID: P14868
• Cytogenetics: 2q21.3
• Domains: tRNA-synt_2, tRNA_anti
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• MW: 57 kDa
• Gene Summary: This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]