S100 beta (S100B) (NM_006272) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200277L2V

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  • LentiORF®

Lenti ORF particles, S100B (mGFP-tagged) - Human S100 calcium binding protein B (S100B), 200ul, >10^7 TU/mL



USD 1,020.00


Availability*
3 Weeks

Size
    • 200 ul


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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol S100B
Synonyms NEF; S100; S100-B; S100beta
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_006272
ORF Size 276 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC200277).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_006272.1, NP_006263.1
RefSeq Size 1135 bp
RefSeq ORF 279 bp
Locus ID 6285
UniProt ID P04271
Cytogenetics 21q22.3
Domains S_100, EFh
MW 10.7 kDa
Gene Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
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