Gfra2 (NM_008115) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR225280L3V
- LentiORF®
Lenti ORF particles, Gfra2 (Myc-DDK-tagged) - Mouse glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Gfra2 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008115 |
ORF Size | 1395 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR225280).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008115.2, NP_032141.2 |
RefSeq Size | 3487 bp |
RefSeq ORF | 1395 bp |
Locus ID | 14586 |
UniProt ID | O08842 |
Cytogenetics | 14 D2 |
Gene Summary | The protein encoded by this gene is part of the receptor complex that transduces glial cell-derived neurotrophic factor and neurturin signals by mediating autophosphorylation and activation of the RET receptor. Mice lacking this protein are viable and fertile but display growth retardation attributed to impaired salivary and pancreatic secretion and innervation deficits in the intestinal tract. In addition, knockout mice display neural defects including a failure to initiate outgrowth of dorsal ganglion root neurons, demonstrating a requirement in neuronal differentiation of these cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] |
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