Rnf152 (NM_001160368) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR223906L3V

Lenti ORF particles, Rnf152 (Myc-DDK-tagged) - Mouse ring finger protein 152 (Rnf152), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Rnf152
• Synonyms: A930029B02Rik
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001160368
• ORF Size: 612 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR223906).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001160368.1, NP_001153840.1
• RefSeq Size: 8406 bp
• RefSeq ORF: 612 bp
• Locus ID: 320311
• UniProt ID: Q8BG47
• Cytogenetics: 1 E2.1
• Gene Summary: E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability (PubMed:25936802). Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed (By similarity).[UniProtKB/Swiss-Prot Function]