Madd (NM_001177720) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR219738L3V

Lenti ORF particles, Madd (Myc-DDK-tagged) - Mouse MAP-kinase activating death domain (Madd), transcript variant 11, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Madd
• Synonyms: 9630059K23Rik; IG20
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001177720
• ORF Size: 4881 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR219738).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001177720.1, NP_001171191.1
• RefSeq Size: 5905 bp
• RefSeq ORF: 4884 bp
• Locus ID: 228355
• UniProt ID: Q80U28
• Cytogenetics: 2 E1
• Gene Summary: Plays a significant role in regulating cell proliferation, survival and death through alternative mRNA splicing. Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms. Component of the TNFRSF1A signaling complex: MADD links TNFRSF1A with MAP kinase activation. Plays an important regulatory role in physiological cell death (TNF-alpha-induced, caspase-mediated apoptosis).[UniProtKB/Swiss-Prot Function]