Acvr2a (NM_007396) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR219492L4V

Lenti ORF particles, Acvr2a (GFP-tagged) - Mouse activin receptor IIA (Acvr2a), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Acvr2a
• Synonyms: ActrIIa; Acvr2; TactrII
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_007396
• ORF Size: 1539 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR219492).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007396.4, NP_031422.3
• RefSeq Size: 5681 bp
• RefSeq ORF: 1542 bp
• Locus ID: 11480
• UniProt ID: P27038
• Cytogenetics: 2 28.38 cM
• Gene Summary: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6 (PubMed:23527555).[UniProtKB/Swiss-Prot Function]