Def6 (NM_027185) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR216879L1V

Lenti ORF particles, Def6 (Myc-DDK-tagged) - Mouse differentially expressed in FDCP 6 (Def6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Def6
• Synonyms: 2410003F05Rik; 6430538D02Rik; AV094905; Ibp; Slat; Slat2; Slat6
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_027185
• ORF Size: 1893 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR216879).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_027185.3, NP_081461.2
• RefSeq Size: 2294 bp
• RefSeq ORF: 1893 bp
• Locus ID: 23853
• UniProt ID: Q8C2K1
• Cytogenetics: 17 A3.3
• Gene Summary: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling. Required for optimal T-cell effector function, lymphocyte homeostasis and the prevention of systemic autoimmunity (By similarity).[UniProtKB/Swiss-Prot Function]