Trim56 (NM_201373) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210354L4V
- LentiORF®
Lenti ORF particles, Trim56 (GFP-tagged) - Mouse tripartite motif-containing 56 (Trim56), 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Trim56 |
Synonyms | A130009K11Rik; Gm452; RNF109 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_201373 |
ORF Size | 2202 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210354).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_201373.4, NP_958761.1 |
RefSeq Size | 3637 bp |
RefSeq ORF | 2205 bp |
Locus ID | 384309 |
UniProt ID | Q80VI1 |
Cytogenetics | 5 G2 |
Gene Summary | E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity. In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets TMEM173/STING to 'Lys-63'-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta. Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling. Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES (By similarity).[UniProtKB/Swiss-Prot Function] |
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