Klhl24 (BC021407) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207762L3V

Lenti ORF particles, Klhl24 (Myc-DDK-tagged) - Mouse kelch-like 24 (Drosophila) (cDNA clone MGC:29441 IMAGE:3965863), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Klhl24
• Synonyms: 1110046J11Rik; 4930429H24Rik; 6530402O20Rik; C85082
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: BC021407
• ORF Size: 1452 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR207762).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: BC021407, AAH21407
• RefSeq Size: 1929 bp
• RefSeq ORF: 1454 bp
• Locus ID: 75785
• Cytogenetics: 16 A3
• Gene Summary: Controls KRT14 levels during keratinocytes differentiation (PubMed:27798626). As part of the BCR(KLHL24) E3 ubiquitin ligase complex, mediates ubiquitination of KRT14 (By similarity). Specifically reduces kainate receptor-mediated currents in hippocampal neurons, most probably by modulating channel properties (By similarity).[UniProtKB/Swiss-Prot Function]