Rbpms (NM_019733) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR201952L4V

Lenti ORF particles, Rbpms (GFP-tagged) - Mouse RNA binding protein gene with multiple splicing (Rbpms), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Rbpms
• Synonyms: 2010300K22Rik; 2700019M19Rik; AU017537; hermes; RBP-MS
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_019733
• ORF Size: 591 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR201952).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019733.3, NP_062707.1
• RefSeq Size: 2569 bp
• RefSeq ORF: 594 bp
• Locus ID: 19663
• UniProt ID: Q9WVB0
• Cytogenetics: 8 A4
• Gene Summary: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.[UniProtKB/Swiss-Prot Function]