KIAA0319 (NM_001168376) Human Untagged Clone

CAT#: SC329262

KIAA0319 (untagged)-Human KIAA0319 (KIAA0319) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KIAA0319
• Synonyms: AAVR; DYLX2; DYX2; NMIG
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001168376, the custom clone sequence may differ by one or more nucleotides
  ATGCGGGTGTCTCACACCTTCCCTGTCGTAGACTGCACGGCCGCTTGCTGTGACCTGTCC
  AGCTGTGACCTGGCCTGGTGGTTCGAGGGCCGCTGCTACCTGGTGAGCTGCCCCCACAAA
  GAGAACTGTGAGCCCAAGAAGATGGGCCCCATCAGGTCTTATCTCACTTTTGTGCTCCGG
  CCTGTTCAGAGGCCTGCACAGCTGCTGGACTATGGGGACATGATGCTGAACAGGGGCTCC
  CCCTCGGGGATCTGGGGGGACTCACCTGAGGATATCAGAAAGGACTTGACCTTTCTAGGC
  AAAGATTGGGGCCTAGAGGAGATGTCTGAGTACTCAGATGACTACCGGGAGCTGGAGAAG
  GACCTCTTGCAACCCAGTGGCAAGCAGGAGCCCAGAGGGAGTGCCGAGTACACGGACTGG
  GGCCTACTGCCGGGCAGCGAGGGGGCCTTCAACTCCTCTGTTGGAGACAGTCCTGCGGTG
  CCAGCGGAGACGCAGCAGGACCCTGAGCTCCATTACCTGAATGAGTCGGCTTCAACCCCT
  GCCCCAAAACTCCCTGAGAGAAGTGTGTTGCTTCCCTTGCCGACTACTCCATCTTCAGGA
  GAGGTGTTGGAGAAAGAAAAGGCTTCTCAGCTCCAGGAACAATCCAGCAACAGCTCTGGA
  AAAGAGGTTCTAATGCCTTCCCATAGTCTTCCTCCGGCAAGCCTGGAGCTCAGCTCAGTC
  ACCGTGGAGAAAAGCCCAGTGCTCACAGTCACCCCGGGGAGTACAGAGCACAGCATCCCA
  ACACCTCCCACTAGCGCAGCCCCCTCTGAGTCCACCCCATCTGAGCTACCCATATCTCCT
  ACCACTGCTCCCAGGACAGTGAAAGAACTTACGGTATCGGCTGGAGATAACCTAATTATA
  ACTTTACCCGACAATGAAGTTGAACTGAAGGCCTTTGTTGCGCCAGCGCCACCTGTAGAA
  ACAACCTACAACTATGAATGGAATTTAATAAGCCACCCCACAGACTACCAAGGTGAAATA
  AAACAAGGACACAAGCAAACTCTTAACCTCTCTCAATTGTCCGTCGGACTTTATGTCTTC
  AAAGTCACTGTTTCTAGTGAAAACGCCTTTGGAGAAGGATTTGTCAATGTCACTGTTAAG
  CCTGCCAGAAGAGTCAACCTGCCACCTGTAGCAGTTGTTTCTCCCCAACTGCAAGAGCTC
  ACTTTGCCTTTGACGTCAGCCCTCATTGATGGCAGCCAAAGTACAGATGATACTGAAATA
  GTGAGTTATCATTGGGAAGAAATAAACGGGCCCTTCATAGAAGAGAAGACTTCAGTTGAC
  TCTCCCGTCTTACGCTTGTCTAACCTTGATCCTGGTAACTATAGTTTCAGGTTGACTGTT
  ACAGACTCGGACGGAGCCACTAACTCTACAACTGCAGCCCTAATAGTGAACAATGCTGTG
  GACTACCCACCAGTTGCTAATGCAGGACCAAATCACACCATAACTTTGCCCCAAAACTCC
  ATCACTTTGAATGGAAACCAGAGCAGTGACGATCACCAGATTGTCCTCTATGAGTGGTCC
  CTGGGTCCTGGGAGTGAGGGCAAACATGTGGTCATGCAGGGAGTACAGACGCCATACCTT
  CATTTATCTGCAATGCAGGAAGGAGATTATACATTTCAGCTGAAGGTGACAGATTCTTCA
  AGGCAACAGTCTACTGCTGTGGTGACTGTGATTGTCCAGCCTGAAAACAATAGACCTCCA
  GTGGCTGTGGCCGGCCCTGATAAAGAGCTGATCTTCCCAGTGGAAAGTGCTACCCTGGAT
  GGGAGCAGCAGCAGCGATGACCACGGCATTGTCTTCTACCACTGGGAGCACGTCAGAGGC
  CCCAGTGCAGTGGAGATGGAAAATATTGACAAAGCAATAGCCACTGTGACTGGTCTCCAG
  GTGGGGACCTACCACTTCCGTTTGACAGTGAAAGACCAGCAGGGACTGAGCAGCACGTCC
  ACCCTCACTGTGGCTGTGAAGAAGGAAAATAATAGTCCTCCCAGAGCCCGGGCTGGTGGC
  AGACATGTTCTTGTGCTTCCCAATAATTCCATTACTTTGGATGGTTCAAGGTCTACTGAT
  GACCAAAGAATTGTGTCCTATCTGTGGATCCGGGATGGCCAGAGTCCAGCAGCTGGAGAT
  GTCATCGATGGCTCTGACCACAGTGTGGCTCTGCAGCTTACGAATCTGGTGGAGGGGGTG
  TACACTTTCCACTTGCGAGTCACCGACAGTCAGGGGGCCTCGGACACAGACACTGCCACT
  GTGGAAGTGCAGCCAGACCCTAGGAAGAGTGGCCTGGTGGAGCTGACCCTGCAGGTTGGT
  GTTGGGCAGCTGACAGAGCAGCGGAAGGACACCCTTGTGAGGCAGCTGGCTGTGCTGCTG
  AACGTGCTGGACTCGGACATTAAGGTCCAGAAGATTCGGGCCCACTCGGATCTCAGCACC
  GTGATTGTGTTTTATGTACAGAGCAGGCCGCCTTTCAAGGTTCTCAAAGCTGCTGAAGTG
  GCCCGAAATCTGCACATGCGGCTCTCAAAGGAGAAGGCTGACTTCTTGCTTTTCAAGGTC
  TTGAGGGTTGATACAGCAGGTTGCCTTCTGAAGTGTTCTGGCCATGGTCACTGCGACCCC
  CTCACAAAGCGCTGCATTTGCTCTCACTTATGGATGGAGAACCTTATACAGCGTTATATC
  TGGGATGGAGAGAGCAACTGTGAGTGGAGTATATTCTATGTGACAGTGTTGGCTTTTACT
  CTTATTGTGCTAACAGGAGGTTTCACTTGGCTTTGCATCTGCTGCTGCAAAAGACAAAAA
  AGGACTAAAATCAGGAAAAAAACAAAGTACACCATCCTGGATAACATGGATGAACAGGAA
  AGAATGGAACTGAGGCCCAAATATGGTATCAAGCACCGAAGCACAGAGCACAACTCCAGC
  CTGATGGTATCCGAGTCTGAGTTTGACAGTGACCAGGACACAATCTTCAGCCGAGAAAAG
  ATGGAGAGAGGGAATCCAAAGGTTTCCATGAATGGTTCCATCAGAAATGGAGCTTCCTTC
  AGTTATTGCTCAAAGGACAGATAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001168376
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001168376.1, NP_001161848.1
• RefSeq Size: 6620 bp
• RefSeq ORF: 3084 bp
• Locus ID: 9856
• UniProt ID: Q5VV43
• Cytogenetics: 6p22.3
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (4) differs in the 5' UTR, lacks an exon and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a. Variants 4 and 10 both encode the same isoform (c). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.