NELL2 (NM_001145109) Human Untagged Clone

CAT#: SC326238

NELL2 (untagged)-Human NEL-like 2 (chicken) (NELL2), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NELL2
• Synonyms: NRP2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001145109, the custom clone sequence may differ by one or more nucleotides
  ATGGAAACGGGACTGGGTGCTCCGCTATTTAAAGCTTGGCTGCTGATCTCAGTTTGGGGG
  CTTGGTGTGGACCCTTCCCTACAGATTGACGTCTTAACAGAGTTAGAACTTGGGGAGTCC
  ACGACCGGAGTGCGTCAGGTCCCGGGGCTGCATAATGGGACGAAAGCCTTTCTCTTTCAA
  GATACTCCCAGAAGCATAAAAGCATCCACTGCTACAGCTGAACAGTTTTTTCAGAAGCTG
  AGAAATAAACATGAATTTACTATTTTGGTGACCCTAAAACAGACCCACTTAAATTCAGGA
  GTTATTCTCTCAATTCACCACTTGGATCACAGGTACCTGGAACTGGAAAGTAGTGGCCAT
  CGGAATGAAGTCAGACTGCATTACCGCTCAGGCAGTCACCGCCCTCACACAGAAGTGTTT
  CCTTACATTTTGGCTGATGACAAGTGGCACAAGCTCTCCTTAGCCATCAGTGCTTCCCAT
  TTGATTTTACACATTGACTGCAATAAAATTTATGAAAGGGTAGTAGAAAAGCCCTCCACA
  GACTTGCCTCTAGGCACAACATTTTGGCTAGGACAGAGAAATAATGCGCATGGATATTTT
  AAGGGTATAATGCAAGATGTCCAATTACTTGTCATGCCCCAGGGATTTATTGCTCAGTGC
  CCAGATCTTAATCGCACCTGTCCAACTTGCAATGACTTCCATGGACTTGTGCAGAAAATC
  ATGGAGCTACAGGATATTTTAGCCAAAACATCAGCCAAGCTGTCTCGAGCTGAACAGCGA
  ATGAATAGATTGGATCAGTGCTATTGTGAAAGGACTTGCACCATGAAGGGAACCACCTAC
  CGAGAATTTGAGTCCTGGATAGACGGCTGTAAGAACTGCACATGCCTGAATGGAACCATC
  CAGTGTGAAACTCTAATCTGCCCAAATCCTGACTGCCCACTTAAGTCGGCTCTTGCGTAT
  GTGGATGGCAAATGCTGTAAGGAATGCAAATCGATATGCCAATTTCAAGGACGAACCTAC
  TTTGAAGGAGAAAGAAATACAGTCTATTCCTCTTCTGGAGTATGTGTTCTCTATGAGTGC
  AAGGACCAGACCATGAAACTTGTTGAGAGTTCAGGCTGTCCAGCTTTGGATTGTCCAGAG
  TCTCATCAGATAACCTTGTCTCACAGCTGTTGCAAAGTTTGTAAAGGTTATGACTTTTGT
  TCTGAAAGGCATAACTGCATGGAGAATTCCATCTGCAGAAATCTGAATGACAGGGCTGTT
  TGTAGCTGTCGAGATGGTTTTAGGGCTCTTCGAGAGGATAATGCCTACTGTGAAGACATC
  GATGAGTGTGCTGAAGGGCGCCATTACTGTCGTGAAAATACAATGTGTGTCAACACCCCG
  GGTTCTTTTATGTGCATCTGCAAAACTGGATACATCAGAATTGATGATTATTCATGTACA
  GAACATGATGAGTGTATCACAAATCAGCACAACTGTGATGAAAATGCTTTATGCTTCAAC
  ACTGTTGGAGGACACAACTGTGTTTGCAAGCCGGGCTATACAGGGAATGGAACGACATGC
  AAAGCATTTTGCAAAGATGGCTGTAGGAATGGAGGAGCCTGTATTGCCGCTAATGTGTGT
  GCCTGCCCACAAGGCTTCACTGGACCCAGCTGTGAAACGGACATTGATGAATGCTCTGAT
  GGTTTTGTTCAATGTGACAGTCGTGCTAATTGCATTAACCTGCCTGGATGGTACCACTGT
  GAGTGCAGAGATGGCTACCATGACAATGGGATGTTTTCACCAAGTGGAGAATCGTGTGAA
  GATATTGATGAGTGTGGGACCGGGAGGCACAGCTGTGCCAATGATACCATTTGCTTCAAT
  TTGGATGGCGGATATGATTGTCGATGTCCTCATGGAAAGAATTGCACAGGGGACTGCATC
  CATGATGGAAAAGTTAAGCACAATGGTCAGATTTGGGTGTTGGAAAATGACAGGTGCTCT
  GTGTGCTCATGTCAGAATGGATTCGTTATGTGTCGACGGATGGTCTGTGACTGTGAGAAT
  CCCACAGTTGATCTTTTTTGCTGCCCTGAATGTGACCCAAGGCTTAGTAGTCAGTGCCTC
  CATCAAAATGGGGAAACTTTGTATAACAGTGGTGACACCTGGGTCCAGAATTGTCAACAG
  TGCCGCTGCTTGCAAGGGGAAGTTGATTGTTGGCCCCTGCCTTGCCCAGATGTGGAGTGT
  GAATTCAGCATTCTCCCAGAGAATGAGTGCTGCCCGCGCTGTGTCACAGACCCTTGCCAG
  GCTGACACCATCCGCAATGACATCACCAAGACTTGCCTGGACGAAATGAATGTGGTTCGC
  TTCACCGGGTCCTCTTGGATCAAACATGGCACTGAGTGTACTCTCTGCCAGTGCAAGAAT
  GGCCACATCTGTTGCTCAGTGGATCCACAGTGCCTTCAGGAACTG
  
• Restriction Sites: Please inquire
• ACCN: NM_001145109
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001145109.1, NP_001138581.1
• RefSeq Size: 3210 bp
• RefSeq ORF: 2448 bp
• Locus ID: 4753
• UniProt ID: Q99435
• Cytogenetics: 12q12
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]
  Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct N-terminus compared to isoform a.