BCL2L12 (NM_138639) Human Untagged Clone

CAT#: SC306055

BCL2L12 (untagged)-Human BCL2-like 12 (proline rich) (BCL2L12), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BCL2L12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_138639 edited
  AGACCCAAAAGCCGATGGGACGGCCCGCTGGGCTGTTCCCGCCCCTATGCCCTTTTTTGG
  GTTTCCGGCCAGAGGCATGCTGGGAGCGTCACATGCAAATTGAGCGTGCACCCAGCGTTC
  CGCCCTTTCTACGCTGGGCCGGTTATCGACCCGGCCCAGTGCGCAGGCGCGGGAAAGTTG
  AACTAATAAAGTTTGTACGAGTTCAGTGGAGGAGACCGCAAGTTGAGTGGAGGAGGCGGC
  GGTGGGGCCCCGGACCAGGTGCCTCCATGGCAGGCTCTGAAGAGCTGGGGCTCCGGGAAG
  ACACGCTGAGGGTCCTAGCTGCCTTCCTTAGGCGTGGTGAGGCTGCCGGGTCTCCTGTTC
  CAACTCCACCTAGAAGCCCTGCCCAAGAAGAGCCAACAGACTTCCTGAGCCGCCTTCGAA
  GATGTCTTCCCTGCTCCCTGGGGCGAGGAGCAGCCCCCTCTGAGTCCCCTCGGCCTTGCT
  CTCTGCCCATCCGCCCCTGCTATGGTTTAGAGCCTGGCCCAGCTACTCCAGACTTCTATG
  CTTTGGTGGCCCAGCGGCTGGAACAGCTGGTCCAAGAGCAGCTGAAATCTCCGCCCAGCC
  CAGAATTACAGGGTCCCCCATCGACAGAGAAGGAAGCCATACTGCGGAGGCTGGTGGCCC
  TGCTGGAGGAGGAGGCAGAAGTCATTAACCAGAAGCTGGCCTCGGACCCCGCCCTGCGCA
  GCAAGCTGGTCCGCCTGTCCTCCGACTCTTTCGCCCGCCTGGTGGAGCTGTTCTGTAGCC
  GGGATGACAGCTCTCGCCCAAGCCGAGCATGCCCCGGGCCCCCGCCTCCTTCCCCGGAGC
  CCCTGGCCCGCCTGGCCCTAGCCATGGAGCTGAGCCGGCGCGTGGCCGGGCTGGGGGGCA
  CCCTGGCCGGACTCAGCGTGGAGCACGTGCACAGCTTCACGCCCTGGATCCAGGCCCACG
  GGGGCTGGGAGGGCATCCTGGCTGTTTCACCCGTGGACTTGAACTTGCCATTGGACTGAG
  CTCTTTCTCAGAAGCTGCTACAAGATGACACCTCATGTCCCTGCCCTCTTCGTGTGCTTT
  TCCAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_138639 unedited
  CCAAGAACTTGAATTTGTNAAACCCACTCACTATAGGNCGGCCGCGCATTCGCCCTTAAA
  GACCCAAAACCGATGGGACGGCCCGCTGGGCTGTTCCCGCCCCTATGCCCTTTTTTGGGT
  TTCCGGCCAGAGGCATGCTGGGAGCGTCACATGCAAATTGAGCGTGCACCCAGCGTTCCG
  CCCTTTCTACGCTGGGCCGGTTATCGACCCGGCCCAGTGCGCAGGCGCGGGAAAGTTGAA
  CTAATAAAGTTTGTACGAGTTCAGTGGAGGAGACCGCAAGTTGAGTGGAGGAGGCGGCGG
  TGGGGCCCCGGACCAGGTGCCTCCATGGCAGGCTCTGAAGAGCTGGGGCTCCGGGAAGAC
  ACGCTGAGGGTCCTAGCTGCCTTCCTTAGGCGTGGTGAGGCTGCCGGGTCTCCTGTTCCA
  ACTCCACCTAGAAGCCCTGCCCAAGAAGAGCCAACAGACTTCCTGAGCCGCCTTCGAAGA
  TGTCTTCCCTGCTCCCTGGGGCGAGGAGCAGCCCCCTCTGAGTCCCCTCGGCCTTGCTCT
  CTGCCCATCCGCCCCTGCTATGGTTTAGAGCCTGGCCCAGCTACTCCAGACTTCTATGCT
  TTGGTGGCCCAGCGGCTGGAACAGCTGGTCCAAGAGCAGCTGANATCTCCGCCCAGCCCA
  GAATTACAGGGTCCCCCATCGACAGAGAAGGAAGCCATACTGCGGAGGCTGGTGGCCCTG
  CTGGAGGAGGAGGCAGAAGTCATTAACCAGAAGCTGGCCTCGGACCCCGCCCTGCGCAGC
  AAGCTGGTCCGCCTGTCCTCCGACTCTTTCGCCCGCCTGGTGGAGCTGTTCTGTAGCCGG
  GATGACAGCTCTCGCCCAGCCGAGCATGCCCCGGGCCCCCGCCTCCTTCCCGGGACCCCT
  GGCCGG
  
• Restriction Sites: Please inquire
• ACCN: NM_138639
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_138639.1, NP_619580.1
• RefSeq Size: 1893 bp
• RefSeq ORF: 1005 bp
• Locus ID: 83596
• UniProt ID: Q9HB09
• Cytogenetics: 19q13.33
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.