DISC1 (NM_018662) Human Untagged Clone

CAT#: SC304621

DISC1 (untagged)-Human disrupted in schizophrenia 1 (DISC1), transcript variant L

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DISC1
• Synonyms: C1orf136; SCZD9
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_018662 edited
  GGGGCGCATGCCAGGCGGGGGTCCTCAGGGCGCCCCAGCCGCCGCCGGCGGCGGCGGCGT
  GAGCCACCGCGCAGGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCG
  GCTGGCACGGAGGCCGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTC
  CCCAGCAGTGGGCACACTGTTCCGGTTCCCAGGAGGGGTGTCTGGCGAGGAGTCCCACCA
  CTCGGAGTCCAGGGCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCC
  TGTTTCCAAGAGTGCAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTT
  TGGGATTCAGCTCAGAGGTGGCACCAGATTGCCTGACAGGCTTAGCTGGCCGTGTGGCCC
  TGGGAGTGCTGGGTGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGC
  CAGCTGGGAGGCAGCCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCC
  ATCAGCAGAGTTGAGTAGCAACAGCTGCAGCCCTGGCTGTGGCCCTGAGGTCCCCCCAAC
  CCCTCCTGGCTCTCACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGG
  CTCTGCCGGGGAACGTGGAGAAGCAGAAGGCTGCCCACCATCCAGAGAGGCTGAGTCCCA
  TTGCCAGAGCCCCCAGGAGATGGGAGCCAAAGCTGCCAGCTTGGACGGGCCTCACGAGGA
  CCCGCGATGTCTCTCTCGGCCCTTCAGTCTCTTGGCTACACGGGTCTCTGCAGACTTGGC
  CCAGGCCGCAAGGAACAGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCAGACATGGA
  CCCTGGCTCCTCCAGTTCTCTGGATCCCTCACTGGCTGGCTGTGGTGGTGATGGGAGCAG
  CGGCTCAGGGGATGCCCACTCTTGGGACACCCTGCTCAGGAAATGGGAGCCAGTGCTGCG
  GGACTGCCTGCTGAGAAACCGGAGGCAGATGGAGGTAATATCCTTAAGATTAAAACTTCA
  GAAACTTCAGGAAGATGCAGTTGAGAATGATGATTATGATAAAGCTGAGACGTTACAACA
  AAGATTAGAAGACCTGGAACAAGAGAAAATCAGCCTGCACTTTCAACTTCCTTCAAGGCA
  GCCAGCTCTTAGCAGTTTCCTGGGTCACCTGGCAGCACAAGTCCAGGCTGCCTTGCGCCG
  TGGGGCCACTCAGCAGGCCAGCGGAGATGACACCCACACCCCACTGAGAATGGAGCCGAG
  GCTGTTGGAACCCACTGCTCAGGACAGCTTGCACGTGTCCATCACGAGACGAGACTGGCT
  TCTTCAGGAAAAGCAGCAGCTACAGAAAGAAATTGAAGCTCTCCAAGCAAGGATGTTTGT
  GCTGGAAGCCAAAGATCAACAGCTGAGAAGGGAAATAGAGGAGCAAGAGCAGCAACTCCA
  GTGGCAGGGCTGCGACCTGACCCCACTGGTGGGCCAGCTGTCCCTGGGTCAGCTGCAGGA
  GGTCAGCAAGGCCTTGCAGGACACCCTGGCCTCAGCCGGTCAGATTCCCTTCCATGCAGA
  GCCACCGGAAACCATAAGGAGCCTCCAGGAAAGAATAAAATCCCTCAACTTGTCACTTAA
  AGAAATCACTACTAAGGTGTGTATGAGTGAGAAATTCTGCAGCACCCTGAGGAAGAAAGT
  TAACGATATTGAAACCCAACTACCAGCCTTGCTTGAAGCCAAAATGCATGCCATATCAGG
  AAACCATTTCTGGACGGCTAAAGACCTCACCGAGGAGATTAGATCATTAACATCAGAGAG
  AGAAGGGCTGGAGGGACTCCTCAGCAAGCTGTTGGTGTTGAGTTCCAGGAATGTCAAAAA
  GCTGGGAAGTGTTAAAGAAGATTACAACAGACTGAGAAGAGAAGTGGAGCACCAGGAGAC
  TGCCTATGAAACAAGTGTGAAGGAAAATACTATGAAGTACATGGAAACACTTAAGAATAA
  ACTGTGCAGCTGCAAGTGTCCACTGCTTGGGAAAGTGTGGGAAGCTGACTTGGAAGCTTG
  TCGATTGCTTATCCAGAGCCTACAGCTCCAGGAAGCCAGGGGAAGCCTGTCTGTAGAAGA
  TGAGAGGCAGATGGATGACTTAGAGGGAGCTGCTCCTCCTATTCCCCCCAGGCTCCACTC
  CGAGGATAAAAGGAAGACCCCTTTGAAGGTATTGGAAGAATGGAAGACTCACCTCATCCC
  CTCTCTGCACTGTGCTGGAGGTGAACAGAAAGAGGAATCTTACATCCTTTCTGCAGAACT
  TGGAGAAAAGTGTGAAGACATAGGCAAGAAGCTATTGTACTTGGAAGATCAACTTCACAC
  AGCAATCCACAGTCATGATGAAGATCTCATTCAGTCTCTCAGGAGGGAGCTCCAGATGGT
  GAAGGAAACTCTGCAGGCCATGATCCTGCAGCTCCAGCCAGCAAAGGAGGCGGGAGAAAG
  AGAAGCTGCAGCTTCCTGCATGACAGCTGGTGTCCACGAAGCACAAGCCTGAGGAGTGAC
  GGGATGGGGGAGGGAGGTGGGCCACCATGTTTGGACCCGGGGGGCTGCTCTTCCCTCCCC
  CGCCATAGCTAAGATGCCTGAATCAATTACGGAGATACAGAGCCTTGAGGTCTTTCAGTG
  GAAAGGTGGTTCATGTTCATTCTCATCAGTGTGAAACTGAGGAGTCTGCAATTTGGAATA
  TGGAGAGAGAGACTGATTTGCTGAATTTCCTTCTAAATGTCACTCAAAAATTTCTTTTCC
  ATGTCATTCTTGAGAATGTCTTCCACAGGATTTGAGAATAGTTTCATCTCAGCCCCCATT
  AGAGAGAAGTTGGGGTGAATTCTGGAAAAATGTCTCTTTTTCCTGTGCCATTTGCCTTCT
  GCTGCAACGAAAATATTTCCTGATTCAAGATTCTATAAAAAGGAAACCAAGCATAAGACT
  CTGTCATCATACCTGTTACACGTTCCTACAGGTGCACAATCTAAGAGAGCTAATTAACCT
  CAGAGTCTGGAGTTAACAGCTTTTCACCTTACTTCTCCTGTGATCTAATATTATCTTAGA
  AAAATTAATATGCAATTTCCAAAAGATATTTTGGTAAGACAACAACCTCCCAGTGATATG
  CCACCTTTCAATTTTCCTTTTGTGGCAATGATTGCATCTGAAGAAAGGATCCCTGAGAGT
  CTCTGTTTCATCAGGACATTCTGAAATTTACCCACAGTGAGGCTGTGGATGGATCAGGGG
  ACCTGTATAAAATGTTTGAGCCTGTTCCATTTTCCCGTGGAACCTGTTTCACTCAATGCC
  AGGCAGTGCAGCATTTAGGAAAGCAGTGCAGTACTCAGTAAGGCAGTGCAGTACTCAGTA
  ACACAATACAGTACTCAGGCAGTGCAGTACTCAGTAAGACAGTGCAGTGCTCAGTAAGGC
  AGTGCAATACTCAGTAACAGTGTAGTACTCAGTAACAGTGAAGTACTCAGTAATACAGTA
  CAGTATTCAGTAAGGCAGTGAAGTACTCAGTAATACAATACAGTACTCAGTTAGGCAGTG
  CAGTACTCAGGAATGCAGCACAGTACTCAGGCAGTGCAATACTCAGTGCGGTACTCAGTA
  ACACAGTGCAGTACTCAGTAACAGTGCAGTACTCAGTAACAGTGCAGTACTCAGTAAGGC
  AGTGCAGTACTCAGTAACACAGTGCAGTACTCAGTAATACAGTACAGTACTCAGTAAGGC
  AGTATGGTACTCAGTAAAGCAATGCAATGCTCAGTAACACAGTGCAGTGCTCAATAAGGC
  AGTGCAGTGCTCAGTAAGGCAGTGAATTGCTTAGTAACACAGTGTAGTGCTCAGTAGGAC
  AGCATAGTACTCAGTAACACAGGGCAGCTAGTACTCAGTACTATAAGTACTGAGTACTTA
  TATAGGCAATGTAGTACTCAGTAAATCAGTGCAGTACTCAGTAATGCAAGGGCATTTCAG
  GCTCCTGCTGGGCTGCTTCTTTGGCCCAGCTGGGACTCCTATTGAGACAGCTGCAAAACA
  GGCTGATTTCAATTAGGCAGCACTTCCCAAAGTGCACTGAGGAAGGTGGCCCCAAGAGAA
  GCTCTCTAAACAAAGGAGTACCCTCTCTGGTCAAGTACCTTTGGTAAATACACCATACCA
  TAATATCTGCTTGGAGAACCACAATGCACATTAGCATATTAGTCTGAGAGAGAACTTATA
  GTAAGGAAACTCACTTGATTTTATCTAACCTCAAACTTTCCAAGTTTAATGGATCGTGAA
  TTTTTTTCATGTAACTCCTATTCATATCCCATAGATCTAGTATTGTACAGCACTGCATTC
  TCTGAGGAAGTCCCAGTCCAAACTCTGATTTACATCACTTTAGAAACCACACTCACACTT
  TTGCAGAGTGTTGAGCTTAATAACTACCTGCCACAGATTGGTAAATTTAATCCAGTGGTT
  GTTCTGTTTGTGCTTCTGTTCTCATTTATGTGTTTAGGGATAGTGAGGTTCCTGCCTTCA
  CTAGGATCCACGGATATGAGACCATTTTTGTCATTTCCTGAAGTCACACTGGCGTTTCCA
  GAAGGCATCTGGTGCTTTGCTCAGCCTTCCATGCTGTGCAGCACTTCTGTCCTCAGTCAA
  GGAGATGGCCATGCTTAAGCCAGCAATTGGCTGGGGTCCAGGAAACAAAGCAAAAGCACA
  ATATGTGAATGTGCTGATTGTGTTCCCTACGGCTTTATCTCGAGAGGCCTCTTGGTCCGG
  AGCCCTGTTTCCAAGAGTGCAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCG
  CACTTTGGGATTCAGCTCAGAGGTGAAGGGCG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018662 unedited
  GCGTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCCCTTAGCGGGGCGCATGCCA
  GGCGGGGGTCCTCAGGGCGCCCCAGCCGCCGCCGGCGGCGGCGGCGTGAGCCACCGCGCA
  GGCAGCCGGGATTGCTTACCACCTGCAGCGTGCTTTCGGAGGCGGCGGCTGGCACGGAGG
  CCGGGCTACATGAGAAGCTCGACAGGGCCTGGGATCGGGTTCCTTTCCCCAGCAGTGGGC
  ACACTGTTCCGGTTCCCAGGAGGGGTGTCTGGCGAGGAGTCCCACCACTCGGAGTCCAGG
  GCCAGACAGTGTGGCCTTGACTCGAGAGGCCTCTTGGTCCGGAGCCCTGTTTCCAAGAGT
  GCAGCAGCCCCTACTGTGACCTCTGTGAGAGGAACCTCGGCGCACTTTGGGATTCAGCTC
  AGAGGTGGCACCAGATTGCCTGACAGGCTTAGCTGGCCGTGTGGCCCTGGGAGTGCTGGG
  TGGCAGCAAGAGTTTGCAGCCATGGATAGTTCTGAGACCCTGGACGCCAGCTGGGAGGCA
  GCCTGCAGCGATGGAGCAAGGCGTGTCCGGGCAGCAGGCTCTCTGCCATCAGCAGAGTTG
  AGTAGCAACAGCTGCAGCCCTGGCTGTGGCCCTGAGGTCCCCCCAACCCCTCCTGGCTCT
  CACAGTGCCTTTACCTCAAGCTTTAGCTTTATTCGGCTCTCGCTTGGCTCTGCCGGGGAA
  CGTGGAGAAGCAGAAGCTGCCCACCATCCAGAGAGGCTGAGTCCCATTGCCAGAGCCCCC
  AGGAGATGGGAGCCAAAGCTGCCAGCTTGGACGGCCTCACGAGGACCCCGCGATGTCTCT
  CTCGGCCCTTCAGTCTTCTTGGCTACACGGGTCTCTGCAGACTTGCCCAGCCGCAAGAAC
  AGCTCCAGGCCAGAGCGTGACATGCATTCTTTACCCAGAACATTGGACCCTGGCTTCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018662 unedited
  CGATGGATGCACTTCAGGGCCGGAGAGGCACTGGGGAGGTGGTCACAGGGCATGCCACCC
  GGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTTGATA
  TCGGTACCAGATCTGAATTCGCCCTTCACCTCTGAGCTGAATCCCAAAGTGCGCCGAGGT
  TCCTCTCACAGAGGTCACAGTAGGGGCTGCTGCACTCTTGGAAACAGGGCTCCGGACCAA
  GAGGCCTCTCGAGATAAAGCCGTAGGGAACACAATCAGCACATTCACATATTGTGCTTTT
  GCTTTGTTTCCTGGACCCCAGCCAATTGCTGGCTTAAGCATGGCCATCTCCTTGACTGAG
  GACAGAAGTGCTGCACAGCATGGAAGGCTGAGCAAAGCACCAGATGCCTTCTGGAAACGC
  CAGTGTGACTTCAGGAAATGACAAAAATGGTCTCATATCCGTGGATCCTAGTGAAGGCAG
  GAACCTCACTATCCCTAAACACATAAATGAGAACAGAAGCACAAACAGAACAACCACTGG
  ATTAAATTTACCAATCTGTGGCAGGTAGTTATTAAGCTCAACACTCTGCAAAAGTGTGAG
  TGTGGTTTCTAAAGTGATGTAAATCAGAGTTTGGACTGGGACTTCCTCAGAGAATGCAGT
  GCTGTACAATACTAGATCTATGGGATATGAATAGGAGTTACATGAAAAAAATTCACGATC
  CATTAAACTTGGAAAGTTTGAGGTTAGATAAAATCAAGTGAGTTTCCTTACTATAAGTTC
  TCTCTCAGACTAATATGCTAATGTGCATTGTGGTTTCTCCAAGCAGATATTTATGGTATG
  GTGTATTTACCAAAGGTACTTGACCCGGAGAGGGTACTCCTTTGTTTAGAGAGCTTCTCT
  TGGGGCCACCTTCCTCAGTGCACTTTGGGAAGTGCTGCCCTAATTGAAATCAGCCTGTTG
  
• Restriction Sites: Please inquire
• ACCN: NM_018662
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_018662.2, NP_061132.2
• RefSeq Size: 7069 bp
• RefSeq ORF: 2565 bp
• Locus ID: 27185
• UniProt ID: Q9NRI5
• Cytogenetics: 1q42.2
• Gene Summary: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (L) encodes isoform L, also known as the 'Long' isoform.