RAB3GAP1 (NM_012233) Human Untagged Clone

CAT#: SC303944

RAB3GAP1 (untagged)-Human RAB3 GTPase activating protein subunit 1 (catalytic) (RAB3GAP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB3GAP1
• Synonyms: P130; RAB3GAP; RAB3GAP130; WARBM1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012233, the custom clone sequence may differ by one or more nucleotides
  ATGGCTGCCGACAGTGAGCCCGAATCCGAGGTATTTGAGATCACGGACTTCACCACTGCC
  TCGGAATGGGAAAGGTTTATTTCCAAAGTTGAAGAAGTCTTGAATGACTGGAAACTGATT
  GGAAACTCTTTGGGAAAGCCACTCGAAAAGGGTATATTTACTTCTGGCACATGGGAAGAG
  AAATCAGATGAAATTTCCTTTGCTGACTTCAAGTTCTCAGTCACTCATCATTATCTTGTA
  CAAGAGTCCACTGATAAAGAAGGAAAGGATGAGTTATTAGAGGATGTTGTTCCACAATCT
  ATGCAAGATTTGCTGGGTATGAATAATGACTTTCCTCCAAGAGCACATTGCCTGGTAAGA
  TGGTATGGGCTACGTGAGTTCGTGGTGATTGCCCCTGCTGCACACAGTGACGCTGTTCTC
  AGCGAATCTAAGTGCAACCTTCTTCTGAGTTCTGTTTCTATTGCCTTGGGAAACACTGGC
  TGTCAGGTGCCACTCTTTGTGCAAATTCACCACAAATGGCGAAGAATGTATGTAGGAGAA
  TGTCAAGGTCCTGGTGTACGAACTGATTTCGAAATGGTTCATCTTAGAAAAGTGCCAAAT
  CAGTACACTCACTTATCAGGTCTGCTGGATATCTTCAAATCAAAGATTGGATGTCCTTTA
  ACTCCATTGCCTCCAGTTAGTATTGCTATTCGATTTACCTATGTACTTCAAGATTGGCAG
  CAGTATTTTTGGCCTCAGCAACCTCCAGACATAGATGCCCTTGTAGGAGGAGAAGTTGGA
  GGCTTGGAGTTTGGCAAGTTACCATTTGGTGCCTGCGAAGATCCTATTAGTGAACTCCAT
  TTAGCTACTACATGGCCTCATCTGACCGAAGGGATCATTGTGGATAATGATGTTTATTCT
  GATTTGGATCCTATTCAAGCTCCACATTGGTCTGTTAGAGTTCGAAAAGCTGAGAATCCT
  CAGTGTTTGCTAGGTGATTTTGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCA
  ACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAAGAAACTGCTGATATA
  ACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTT
  TCAAATATGGTACACACTGCAAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCA
  CCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTCCCTGATGCTGTTTCT
  GAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAA
  GACTATAATCTCTACAATCAGTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTG
  GCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAAGGAGTGGCACACCTC
  TGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGA
  TTAGCAAGTGGACCCCCAGATCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTA
  AATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAGACAAGTGCTTCAGAT
  GTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAAT
  CTAAAAGAAACAGATAAGGAAAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGAC
  AGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTTAAAGGAAATGGACAA
  GAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTC
  TATCAGCATGGGAAACTTACACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACC
  CAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCTGAAGTTTTAGCTAAA
  TTAGGTACATCGGCAGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTC
  TCAGATATGGAGTCTTTTAAGGCAGCTAATCCAGGTTGCTCCCTGGAAGATTTTGTGAGG
  TGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAAAAGGGCAATGTGGTG
  CTGAAAGGAGAACTGAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGG
  GAAACAGCTAAGCCAATTCCTGCTAGAAGGCAAAGGAGACTCTTTGATGATACACGGGAA
  GCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGACCTTGCTCGGCACCTG
  TTACCTTGTGTGATTCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAAC
  ATTTCTTCAGTTAAGAAGATCATAAAGCAGATAATATCCCATTCCAGTAAAGTTTTGCAC
  TTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAGATTACTAATGTGGAA
  GCTCTCATTGCCAGAGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAG
  GAGGAGGAAAAGGAAGATCTTGAAAGGTTTGTGAGTTGCCTGCTGGAGCAGCCTGAAGTG
  TTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCACAAGCTGTTTGTGAAT
  GCCCAGAGGGCTGCAGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGCTCCCCA
  GAGGAAAGAAGGCAGAACTCCGTGTCAGACTTCCCACCCCCTGCTGGCCGGGAATTCATT
  TTGCGCACCACTGTGCCGCGCCCTGCTCCCTACTCCAAAGCTCTGCCTCAGCGGATGTAC
  AGTGTTCTCACCAAAGAGGACTTTAGACTTGCAGGTGCCTTTTCATCAGATACTTCCTTC
  TTCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_012233
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012233.1, NP_036365.1
• RefSeq Size: 4179 bp
• RefSeq ORF: 2946 bp
• Locus ID: 22930
• UniProt ID: Q15042
• Cytogenetics: 2q21.3
• Gene Summary: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.