DCXR (NM_016286) Human Untagged Clone

CAT#: SC128260

DCXR (untagged)-Human dicarbonyl/L-xylulose reductase (DCXR), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DCXR
• Synonyms: DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_016286 edited
  ATGGAGCTGTTCCTCGCGGGCCGCCGGGTGCTGGTCACCGGGGCAGGCAAAGGTATAGGG
  CGCGGCACGGTCCAGGCGCTGCACGCGACGGGCGCGCGGGTGGTGGCTGTGAGCCGGACT
  CAGGCGGATCTTGACAGCCTTGTCCGCGAGTGCCCGGGGATAGAACCCGTGTGCGTGGAC
  CTGGGTGACTGGGAGGCCACCGAGCGGGCGCTGGGCAGCGTGGGCCCCGTGGACCTGCTG
  GTGAACAACGCCGCTGTCGCCCTGCTGCAGCCCTTCCTGGAGGTCACCAAGGAGGCCTTT
  GACAGATCCTTTGAGGTGAACCTGCGTGCGGTCATCCAGGTGTCGCAGATTGTGGCCAGG
  GGCTTAATAGCCCGGGGAGTCCCAGGGGCCATCGTGAATGTCTCCAGCCAGTGCTCCCAG
  CGGGCAGTAACTAACCATAGCGTCTACTGCTCCACCAAGGGTGCCCTGGACATGCTGACC
  AAGGTGATGGCCCTAGAGCTCGGGCCCCACAAGATCCGAGTGAATGCAGTAAACCCCACA
  GTGGTGATGACGTCCATGGGCCAGGCCACCTGGAGTGACCCCCACAAGGCCAAGACTATG
  CTGAACCGAATCCCACTTGGCAAGTTTGCTGAGGTAGAGCACGTGGTGAACGCCATCCTC
  TTTCTGCTGAGTGACCGAAGTGGCATGACCACGGGTTCCACTTTGCCGGTGGAAGGGGGC
  TTCTGGGCCTGCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016286 unedited
  GGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGCCGACTGGAG
  CTGTTCCTCGCGGGCCGCCGGGTGCTGGTCACCGGGGCAGGCAAAGGTATAGGGCGCGGC
  ACGGTCCAGGCGCTGCACGCGACGGGCGCGCGGGTGGTGGCTGTGAGCCGGACTCAGGCG
  GATCTTGACAGCCTTGTCCGCGAGTGCCCGGGGATAGAACCCGTGTGCGTGGACCTGGGT
  GACTGGGAGGCCACCGAGCGGGCGCTGGGCAGCGTGGGCCCCGTGGACCTGCTGGTGAAC
  AACGCCGCTGTCGCCCTGCTGCAGCCCTTCCTGGAGGTCACCAAGGAGGCCTTTGACAGA
  TCCTTTGAGGTGAACCTGCGTGCGGTCATCCAGGTGTCGCAGATTGTGGCCAGGGGCTTA
  ATAGCCCGGGGAGTCCCAGGGGCCATCGTGAATGTCTCCAGCCAGTGCTCCCAGCGGGCA
  GTAACTAACCATAGCGTCTACTGCTCCACCAAGGGTGCCCTGGACATGCTGACCAAGGTG
  ATGGCCCTAGAGCTCGGGCCCCACAAGATCCGAGTGAATGCAGTAAACCCCACAGTGGTG
  ATGACGTCCATGGGCCAGGCCACCTGGAGTGACCCCCACAAGGCCAAGACTATGCTGAAC
  CGAATCCCACTTGGCAAGTTTGCTGAGGTAGAGCACGTGGTGAACGCCATCCTCTTTCTG
  CTGAGTGACCGAAGTGGCATGACCACGGGTTCCACTTTGCCCGTGAAAGGGGGGCTTCTG
  GCCTGCTGAGCTCCCTNCAACACCTCAAGCCCATGCCGTGCTCATCCTACCCCCATCCCT
  NNCATAACCTGATTCTGCTGCCCAAAAAAANNAAAAAAAANNANAAANAAAACCTGACTC
  TAGATGCGGNCCGCGTCATAGCTGNTCCTGACAGAACCCGGTGGCATCCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016286 unedited
  NCCCCTTGGGGATGGCAACTNCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGGATG
  CCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGCAGCAAAATCAGGTTTATTGGAGGGA
  TTGGGGGTAGGATGAGCACGGCATGGGGCTTGAGGTGTGTGGAGGGAGCTCAACAGGCCC
  AGAAGCCCCCTTCCACCGGCAAAGTGGAACCCGTGGTCATGCCACTTCGGTCACTCAGCA
  AAAAGAGGATGGCGTTCACCACGTGCTCTACCTCAACAAACTTGCCAAGTGGGATTCGGT
  TCAACATAATCTTGGCCTTGTGGGGGTCACTCCAGGTGGCCTGGCCCATGGACGTCATCA
  CCACTGTGGGGTTTACTGCATTCACTCGGATCTTGTGGGGCCCGAGCTCTAGGGCCATCA
  CCTTGGTCAGCATGTCCAGGGCACCCTTGGTGGAGCAGTAGACGCTATGGTTAGTTACTG
  CCCGCTGGGAGCACTGGCTGGAGACATTCACGATGGCCCCTGGGACTCCCCGGGCTATTA
  AGCCCCTGGCCACAATCTGCGACACCTGGATGACCGCACGCAGGTTCACCTCAAAGGATC
  TGTCAAAGGCCTCCTTGGTGACCTCCAAGAAGGGCTGCAGCAGGGCGACAGCGGCGTTGT
  TCACCAGCAGGTCCACGGGGCCCACGCTGCCCAGCGCCCGCTCGGTGGCCTCCCAGTCAC
  CCAGGTCCACGCACACGGGTTCTATCCCCGGGCACTCGCGGACAAAGCTGTCAAGATCCG
  CCTGAGTTCCGCTCACACCACCACCCGCGCGCCCGTTGCGTGCAGCGCCTGGACCGTGCC
  GCGCCTATACCTTTTGCTGGNCCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016286
• Insert Size: 900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016286.2, NP_057370.1
• RefSeq Size: 829 bp
• RefSeq ORF: 735 bp
• Locus ID: 51181
• UniProt ID: Q7Z4W1
• Cytogenetics: 17q25.3
• Domains: adh_short
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pentose and glucuronate interconversions
• Gene Summary: The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).