Monoamine Oxidase A (MAOA) (NM_000240) Human Untagged Clone

CAT#: SC126927

MAOA (untagged)-Human monoamine oxidase A (MAOA), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Monoamine Oxidase A
• Synonyms: BRNRS; MAO-A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126927 sequence for NM_000240 edited (data generated by NextGen Sequencing)
  ATGGAGAATCAAGAGAAGGCGAGTATCGCGGGCCACATGTTCGACGTAGTCGTGATCGGA
  GGTGGCATTTCAGGACTATCTGCTGCCAAACTCTTGACTGAATATGGCGTTAGTGTTTTG
  GTTTTAGAAGCTCGGGACAGGGTTGGAGGAAGAACATATACTATAAGGAATGAGCATGTT
  GATTACGTAGATGTTGGTGGAGCTTATGTGGGACCAACCCAAAACAGAATCTTACGCTTG
  TCTAAGGAGCTGGGCATAGAGACTTACAAAGTGAATGTCAGTGAGCGTCTCGTTCAATAT
  GTCAAGGGGAAAACATATCCATTTCGGGGCGCCTTTCCACCAGTATGGAATCCCATTGCA
  TATTTGGATTACAATAATCTGTGGAGGACAATAGATAACATGGGGAAGGAGATTCCAACT
  GATGCACCCTGGGAGGCTCAACATGCTGACAAATGGGACAAAATGACCATGAAAGAGCTC
  ATTGACAAAATCTGCTGGACAAAGACTGCTAGGCGGTTTGCTTATCTTTTTGTGAATATC
  AATGTGACCTCTGAGCCTCACGAAGTGTCTGCCCTGTGGTTCTTGTGGTATGTGAAGCAG
  TGCGGGGGCACCACTCGGATATTCTCTGTCACCAATGGTGGCCAGGAACGGAAGTTTGTA
  GGTGGATCTGGTCAAGTGAGCGAACGGATAATGGACCTCCTCGGAGACCAAGTGAAGCTG
  AACCATCCTGTCACTCACGTTGACCAGTCAAGTGACAACATCATCATAGAGACGCTGAAC
  CATGAACATTATGAGTGCAAATACGTAATTAATGCGATCCCTCCGACCTTGACTGCCAAG
  ATTCACTTCAGACCAGAGCTTCCAGCAGAGAGAAACCAGTTAATTCAGCGTCTTCCAATG
  GGAGCTGTCATTAAGTGCATGATGTATTACAAGGAGGCCTTCTGGAAGAAGAAGGATTAC
  TGTGGCTGCATGATCATTGAAGATGAAGATGCTCCAATTTCAATAACCTTGGATGACACC
  AAGCCAGATGGGTCACTGCCTGCCATCATGGGCTTCATTCTTGCCCGGAAAGCTGATCGA
  CTTGCTAAGCTACATAAGGAAATAAGGAAGAAGAAAATCTGTGAGCTCTATGCCAAAGTG
  CTGGGATCCCAAGAAGCTTTACATCCAGTGCATTATGAAGAGAAGAACTGGTGTGAGGAG
  CAGTACTCTGGGGGCTGCTACACGGCCTACTTCCCTCCTGGGATCATGACTCAATATGGA
  AGGGTGATTCGTCAACCCGTGGGCAGGATTTTCTTTGCGGGCACAGAGACTGCCACAAAG
  TGGAGCGGCTACATGGAAGGGGCAGTTGAGGCTGGAGAACGAGCAGCTAGGGAGGTCTTA
  AATGGTCTCGGGAAGGTGACCGAGAAAGACATCTGGGTACAAGAACCTGAATCAAAGGAC
  GTTCCAGCGGTAGAAATCACCCACACCTTCTGGGAAAGGAACCTGCCCTCTGTTTCTGGC
  CTGCTGAAGATCATTGGATTTTCCACATCAGTAACTGCCCTGGGGTTTGTGCTGTACAAA
  TACAAGCTCCTGCCACGGTCTTGA
  
  Clone variation with respect to NM_000240.2
  891 g=>t;1410 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000240 unedited
  GCGAATTCGGCACCAGCAGGAGCGTGTCAGCCAAAGCTTGGAGAATCAAGAGAAGGCGAG
  TATCGCGGGCCACATGTTCGACGTAGTCGTGATCGGAGGTGGCATTTCAGGACTATCTGC
  TGCCAAACTCTTGACTGAATATGGCGTTAGTGTTTTGGTTTTAGAAGCTCGGGACAGGGT
  TGGAGGAAGAACATATACTATAAGGAATGAGCATGTTGATTACGTAGATGTTGGTGGAGC
  TTATGTGGGACCAACCCAAAACAGAATCTTACGCTTGTCTAAGGAGCTGGGCATAGAGAC
  TTACAAAGTGAATGTCAGTGAGCGTCTCGTTCAATATGTCAAGGGGAAAACATATCCATT
  TCGGGGCGCCTTTCCACCAGTATGGAATCCCATTGCATATTTGGATTACAATAATCTGTG
  GAGGACAATAGATAACATGGGGAAGGAGATTCCAACTGATGCACCCTGGGAGGCTCAACA
  TGCTGACAAATGGGACAAAATGACCATGAAAGAGCTCATTGACAAAATCTGCTGGACAAA
  GACTGCTANGCGGGTTGCTTATCTTTTTGTGAATATCAATGTGACCTCTGAGCCTCACGA
  AGTGTCTGNCCTGTGGGTCTTTGTGGTATGTGAAGCAGTGCGGGGGCACCACTCNGATAT
  TCTCTGTCACCAATGGTGGCCAGGAACCGAAGTTTGTANGTGGATCTGGTCAAGTGAGCG
  AACGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000240 unedited
  NNNTTGGTGGCAGTGCACCTTTTTAACAAACAAACAGTACCATACAGGGCAAAATCTTAC
  TTCAGTGGCAAAGCACACACATAGGTATACTCCAACGTGTAGCACTGGGGCAAACTTCAG
  ACATGGAACATTAGGCACCAAGTTCACAATCACACTAAACATAGTTCACAATCCTTCAAT
  CCATACTCTTCAGTGGAGGATGAGGCCTTATTTAACAGTTAACTGGGACAGACAGATGAA
  GTTTTAAAATCTAATTCTTGGCCTAACTGTGGAGTGGGGCTGACTCAGCCTTCAGAACTG
  TGAAGTGGATGCCTTAACAGGGCCAAGATCTATCAGCCTCTTAAACTGACTTTCATTTCT
  CTGGTTCAGAGAAAAAGCTTATGGTATCTTCACGTTGGATGAACTTGCATATCGTGAGAG
  TCCTCAGCTCCAATTTCGTGTCTAGGCACATCTGGACTGGCATTCATTTTGATACCCAAT
  CCATAGATTAATAGGGTTAATCTAATTAGAATAAATTAAATCGTTTTCCAAAAAGTTGAA
  AAGGGTAAATCACATGAGNTCTTCAACATTCAAGACTTTAAATATGTTAGCAAACTGATT
  ACTGTTCCAACTGTTGCCAGTTAAGAAGTTTAAATCAGCATTTTCCCAAAGGTGTGTCAA
  GACTGAGTTAATCAGTTAGCTAATAGAAACAACTGCCATAGACTAGGGGTGAGATTTCTC
  AAAGCAGTCTGATTTATATGGCGCAACTCCTTATGGACTGGAGCGTTTCCAATACATTCT
  CAAAACTTCTTATTTACCTAAAATGCAAGGTAAAGAACCGTTGAAAAATGGCCCTCTTTA
  GGTAGGCCAAACTTTGGAGATATTAGTTCCTCCACCAAGGGCCCCCACTTTGGTTGAATT
  TTGGGAAAGGGTAAGGATAAAAACCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000240
• Insert Size: 4530 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000240.2, NP_000231.1
• RefSeq Size: 4090 bp
• RefSeq ORF: 1584 bp
• Locus ID: 4128
• UniProt ID: P21397
• Cytogenetics: Xp11.3
• Domains: Amino_oxidase
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism
• Gene Summary: This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.