Endothelin 2 (EDN2) (NM_001956) Human Untagged Clone

CAT#: SC126372

EDN2 (untagged)-Human endothelin 2 (EDN2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Endothelin 2
• Synonyms: ET-2; ET2; PPET2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001956 edited
  CCAGCCTGCGCGCTCCACCGCCGCTATGGTCTCCGTGCCTACCACCTGGTGCTCCGTTGC
  GCTAGCCCTGCTCGTGGCCCTGCATGAAGGGAAGGGCCAGGCTGCTGCCACCCTGGAGCA
  GCCAGCGTCCTCATCTCATGCCCAAGGCACCCACCTTCGGCTTCGCCGTTGCTCCTGCAG
  CTCCTGGCTCGACAAGGAGTGCGTCTACTTCTGCCACTTGGACATCATCTGGGTGAACAC
  TCCTGAACAGACAGCTCCTTACGGCCTGGGAAACCCGCCAAGACGCCGGCGCCGCTCCCT
  GCCAAGGCGCTGTCAGTGCTCCAGTGCCAGGGACCCCGCCTGTGCCACCTTCTGCCTTCG
  AAGGCCCTGGACTGAAGCCGGGGCAGTCCCAAGCCGGAAGTCCCCTGCAGACGTGTTCCA
  GACTGGCAAGACAGGGGCCACTACAGGAGAGCTTCTCCAAAGGCTGAGGGACATTTCCAC
  AGTCAAGAGCCTCTTTGCCAAGCGACAACAGGAGGCCATGCGGGAGCCTCGGTCCACACA
  TTCCAGGTGGAGGAAGAGATAGTGTCGTGAGCTGGAGGAACATTGGGAAGGAAGCCCGCG
  GGGAGAGAGGAGGAGAGAAGTGGCCAGGGCTTGTGGACTCTCTGCCTGCTTCCTGGACCG
  GGGCCTTGGTCCCAGACAGCTGGACCCATTTGCCAGGATTGGCACAAGCTCCCTGGTGAG
  GGAGCCTCGTCCAAGGCAGTTCTGTGTCCTCGCACTGCCCAGGGAAGCCCTCGGCCTCCA
  GACTGCGGAGCAGCCTCCAGTGCTGGCTGCTGGCCCACAGCTCTGCTGGAAGAACTGCAT
  GGGGAGTACATTCATCTGGAGGCTGCGTCCTGAGGAGTGTCCTGTCTGCTGGGCTACAAA
  CCAGGAGCAACCGTGCAGCCACGAACACGCATGCCTCAGCCAGCCCTGGAGGCTGGATGG
  CTCCCCTGAGGCTGGCATCCTGGCTGGCTGTGTCCTCTCCAGCTTTCCCTCCCCAGAGTT
  CTTGCACCCTCATTCCCTCGGGACCCTCCCAGTGAGAAGGGCCTGCTCTGCTTTTCCTGT
  CTGTATATAACTTATTTGCCCTAAGAACTTTGAGAATCCCAATTATTTATTTTAATGTAT
  TTTTTAGACCCTCTATTTACCTGCGAACTTGTGTTTATAATAAATGAGGAAACATAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001956 unedited
  GGCGTCACATTTGTAAACGACTTACTATAGGCGGCCGCGCAATCAAATCTGGTACCGGTC
  CGGAATTCCCGGGATCCAGCCTGCGCGCTCCACCGCCGCTATGGTCTCCGTGCCTACCAC
  CTGGTGCTCCGTTGCGCTAGCCCTGCTCGTGGCCCTGCATGAAGGGAAGGGCCAGGCTGC
  TGCCACCCTGGAGCAGCCAGCGTCCTCATCTCATGCCCAAGGCACCCACCTTCGGCTTCG
  CCGTTGCTCCTGCAGCTCCTGGCTCGACAAGGAGTGCGTCTACTTCTGCCACTTGGACAT
  CATCTGGGTGAACACTCCTGAACAGACAGCTCCTTACGGCCTGGGAAACCCGCCAAGACG
  CCGGCGCCGCTCCCTGCCAAGGCGCTGTCAGTGCTCCAGTGCCAGGGACCCCGCCTGTGC
  CACCTTCTGCCTTCGAAGGCCCTGGACTGAAGCCGGGGCAGTCCCAAGCCGGAAGTCCCC
  TGCAGACGTGTTCCAGACTGGCAAGACAGGGGCCACTACAGGAGAGCTTCTCCAAAGGCT
  GAGGGACATTTCCACAGTCAAGAGCCTCTTTGCCAAGCGACAACAGGAGGCCATGCGGGA
  GCCTCGGTCCACACATTCCAGGTGGAGGAAGAGATAGTGTCGTGAGCTGGAGGAACATTG
  GGAAGGAAGCCCGCGGGGAGAGAGGAGGAGAAGAGTGGCCAGGGCTTGTGGACTCTCTGC
  CTGCTTCCTGGACCGGGCCTTGGTCCCAGACAGCTGGACCCATTTGCCAGGATTGGCACA
  AGCTCCCTGGTGAGGGAGCCTCGTCCAANGCAGNTCTGTGTCCTCGCACTGCCCAGGAAG
  CCCTCGCCTCCAGACGNGGAGCAGCCTNCATGCTGGCTGCTGGCCCAAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001956
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001956.2, NP_001947.1
• RefSeq Size: 1296 bp
• RefSeq ORF: 537 bp
• Locus ID: 1907
• UniProt ID: P20800
• Cytogenetics: 1p34.2
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).