IL28 Receptor alpha (IFNLR1) (BC024651) Human Untagged Clone

CAT#: SC126092

(untagged)-Human cDNA clone MGC:25116 IMAGE:4509288, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNLR1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC024651 edited
  GTTTTATTTAGTACACAGGCAAGCAGCATAATCCAGTTTGTATTTTAGAAAGATCATATC
  AGTTGCTGTATGGAAACTAGATTGGAAGGGCCAGGAGAGGACCCAAGGAGGCCATTCTGT
  TATTTAGGGAAGAGATGATGGTGGTGTGGATCGGGTTGTGGTTGGTGGAGGAGGAGAGAA
  GTGCACAGATTGTAGAAGTGTTTTATAAGCAGTCAAGATTTGTCGATGGAGTACATGTGG
  GCAGTGCTCAAGATTGTGTCCCACATTTCTTTTTTTCTTTTTTTTTTTTGTTTGATTGGG
  ATGGAGTCTCACTGTATTGCCCAGGCTGGAGTTCAGTGGCACCATCTCGGCTTACTGCAG
  CCTCCACCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGGGTACCTGGGGCTAC
  AGGCGCCCGCTACCACACCCAGCTAATTTTTGTATTTTTAATAGACATGAGGTTTCGCCA
  TGTTGGCCAGGCTGTTCTCGAACTCCTGACCTCAAATGATCTGCCCGCCTCAGCCTCCCA
  AAGTGCTGAGATTACAAGTGTGAGCCACTGTGCCCGGCCTTAAATTTCTGATGGAAGGGT
  GCCATATACCGAGAAGGGGAAATCTGGCAGGGGAACAGGTTTGGGGAGAAATCAAGAATT
  CTATTTTTTTTTTAATTTTTTGTTTTTTAGAGACAGGGTCTCCTTCTTTTGCCCAGGCTG
  GAATGCAGTGGTGCAGTCATAGCTCACCACAGCCTTGAATTCCTGGGCTTAAGCAATCCT
  CGTGCTTCCACAGGCACATGCCACCACATCCATGCTAATTTGTTTCTTCTCTTGGTAAAG
  ATGAGGTCTCGCTGTGTTGCCTAGGCTGGTTTCAAACTCTTGGGCTTAAGTGATCCTCTT
  GCCTTGGCCTCCCAAAATGTTAGGGTTACAAGCATGAGCCACTTGTGCCTGGCCAAGAAT
  TCTATCTGTATATCTTTATAGGTCTTGAGACATCCAAGTGGAGATGTCAAGAAGGCAGTA
  TGTGAGTTTGGAATTCAAAGGAGCGGGCTGGAGATACACATTTGAGAGCTGTTAGCATCG
  AGACCGTGGGTTTCAAACCTGCATCTGTGTCAGAATCACTTGGCGTCATTCCCAGAGAGT
  ATGATTCAGTGGTGGTATCTTAGGCTTTTAATGGCAAGCAAGAGAAACCATCCTGAGCTG
  ATTTAAGCAGAAAAGGGCTGCACTGAAAGGGAATGTTCAGTAGTTCACAGAATTTCTGGG
  AAGTTGGAAAACTGGGGCTGGGCAGCAGGCAGGATCTCAGCCAAAATCATGCCACCGAGC
  CAGTTTGGCAGGACACTGCTGCCACACACTAAATGCCATCGCTGTGTCACTGTTCCCTGA
  ACACTAGACACCATTGCTGTGGTTGCCACCAGCATTGGAATGGATCTTCCACTGTGCTCC
  TGATTCAAAGTCTGTAGTGAGGGCTTCTGATTGGTTGAGCTTAGGTGTAAGGGAGGCTGG
  AAAAGCAAGAATTTGTTGTTTTCAGCTTTCACAGGAGGTGAACTCTGCCAAGACCTGTGC
  AGTGAGGAAGTCCCCAGACATAGGAAGGAGGTCAGATGCCAGACTGGCACACAATGACAG
  ATGTACTTGACAGCAAGTTTGCCAGCTTGTGGGATTGTCTGGGAATCTGCATTTAAACCA
  GCACCCTGGAAATTCCCATGCAGGTGCTGCCTGAACCACATTTGCATCCATTGCTTGAAC
  TGGTACTTAAAGCTGTGGGGGCTGGGCGCGGTGGCCCACGCCCGTAATCCCAGCACTTTG
  GGAGGCTGAGGCAGGGGGACCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATG
  GCGAAACCCCGTCTCACTAGAAATGCAAAAAATTAGCCGGGCGTGGTGGCACGCACCTGT
  AGTCCCAGCTATTCGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGGTTG
  CAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGTGAAAGGGCAAGACTGTGTCTC
  AAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC024651 unedited
  GGTTCTGATTTGTATACGACTCACTATAGGCGGCCGCGTAATCAGATCTGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGGTTTTATTTAGTACACAGGCAAGCAG
  CATAATCCAGTTTGTATTTTAGAAAGATCATATCAGTTGCTGTATGGAAACTAGATTGGA
  AGGGCCAGGAGAGGACCCAAGGAGGCCATTCTGTTATTTAGGGAAGAGATGATGGTGGTG
  TGGATCGGGTTGTGGTTGGTGGAGGAGGAGANAANTGCACANATTGNANAANTGTTTTAT
  AAGCAGTCAAGATTTGTCGATGGAGTACATGTGGGCAGTGCTCAAGATTGTGTCCCACAT
  TTCTTTTTTTCTTTTTTTTTTTTGTTTGATTGGGATGGAGTCTCACTGTATTGCCCAGGC
  TGGAGTTCAGTGGCACCATCTCGGCTTACTGCAGCCTCCACCTCCCGGGTTCAAAGCGAT
  TCTCCTGCCTCAGCCTCCCGGGTACCTGGGGCTACAGGCGCCCGCTACCACACCCAGCTA
  ATTTTTGTATTTTTAAAAAACATGAAGTTTCCCCATGGTGGGCAAGCTTGTTTCGAACCT
  CTGAACCCAAAAGATTTGCCCGCCTCAGCCTCCCAAAAGGCGGAGATTACAGGGGGGAGC
  CACTGGGCCCCGGGCCTAAAATTTTGAGGGAAGGGGGCCCTATTCCCAGAAAGGGGAAAA
  TTGGCAGGGAAACCAGTTTGGGGAGAAAAACAGAAATCCTATTTATATCTTAAGTTTGTG
  GTTTGGTAGAGACGGGGTCTCCTTTTTTTGGCCACCCGGTGAAGCCCCGTGGAGCGGGCT
  AGAGTCTACCACCGCTTTGGAGTACCGGACATGTAAGAAACCGGGTGGGTAACCAGGNAC
  CATGGCCACCACATCCCATCATAATTAGTTTAT
  
• Restriction Sites: Please inquire
• ACCN: BC024651
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC024651.1
• RefSeq Size: 2059 bp
• Locus ID: 163702
• Cytogenetics: 1p36.11
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]