Bile salt activated lipase (CEL) (BC042510) Human Untagged Clone

CAT#: SC125747

CEL (untagged)-Human carboxyl ester lipase (bile salt-stimulated lipase), mRNA (cDNA clone MGC:35409 IMAGE:5187959), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Bile salt activated lipase
• Synonyms: BAL; bile-salt-activated lipase; bile salt-dependent lipase, oncofetal isoform; bile salt-stimulated carboxyl ester lipase; bile salt-stimulated lipase; BSDL; BSSL; carboxy; carboxyl ester hydrolase; CEase; CELL; FAP; FAPP; LIPA; MODY8; OTTHUMP00000022450
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC042510 edited
  GATGCTCACCATGGGGCGCCTGCAACTGGTTGTGTTGGGCCTCACCTGCTGCTGGGCAGT
  GGCGAGTGCCGCGAAGCTGGGCGCCGTGTACACAGAAGGTGGGTTCGTGGAAGGCGTCAA
  TAAGAAGCTCGGCCTCCTGGGTGACTCTGTGGACATCTTCAAGGGCATCCCCTTCGCAGC
  TCCCACCAAGGCCCTGGAAAATCCTCAGCCACATCCTGGCTGGCAAGGGACCCTGAAGGC
  CAAGAACTTCAAGAAGAGATGCCTGCAGGCCACCATCACCCAGGACAGCACCTACGGGGA
  TGAAGACTGCCTGTACCTCAACATTTGGGTGCCCCAGGGCAGGAAGCAAGTCTCCCGGGA
  CCTGCCCGTTATGATCTGGATCTATGGAGGCGCCTTCCTCATGGGGTCCGGCCATGGGGC
  CAACTTCCTCAACAACTACCTGTATGACGGCGAGGAGATCGCCACACGCGGAAACGTCAT
  CGTGGTCACCTTCAACTACCGTGTCGGCCCCCTTGGGTTCCTCAGCACTGGGGACGCCAA
  TCTGCCAGGTAACTATGGCCTTCGGGATCAGCACATGGCCATTGCTTGGGTGAAGAGGAA
  TATCGCGGCCTTCGGGGGGGACCCCAACAACATCACGCTCTTCGGGGAGTCTGCTGGAGG
  TGCCAGCGTCTCTCTGCAGACCCTCTCCCCCTACAACAAGGGCCTCATCCGGCGAGCCAT
  CAGCCAGAGCGGCGTGGCCCTGAGTCCCTGGGTCATCCAGAAAAACCCACTCTTCTGGGC
  CAAAAAGGTGGCTGAGAAGGTGGGTTGCCCTGTGGGTGATGCCGCCAGGATGGCCCAGTG
  TCTGAAGGTTACTGATCCCCGAGCCCTGACGCTGGCCTATAAGGTGCCGCTGGCAGGCCT
  GGAGTACCCCATGCTGCACTATGTGGGCTTCGTCCCTGTCATTGATGGAGACTTCATCCC
  CGCTGACCCGATCAACCTGTACGCCAACGCCGCCGACATCGACTATATAGCAGGCACCAA
  CAACATGGACGGCCACATCTTCGCCAGCATCGACATGCCTGCCATCAACAAGGGCAACAA
  GAAAGTCACGGAGGACTTCTACAAGCTGGTCAGTGAGTTCACAATCACCAAGGGGCTCAG
  AGGCGCCAAGACGACCTTTGATGTCTACACCGAGTCCTGGGCCCAGGACCCATCCCAGGA
  GAATAAGAAGAAGACTGTGGTGGACTTTGAGACCGATGTCCTCTTCCTGGTGCCCACCGA
  GATTGCCCTAGCCCAGCACAGAGCCAATGCCAAGAGTGCCAAGACCTACGCCTACCTGTT
  TTCCCATCCCTCTCGGATGCCCGTCTACCCCAAATGGGTGGGGGCCGACCATGCAGATGA
  CATTCAGTACGTTTTCGGGAAGCCCTTCGCCACCCCCACGGGCTACCGGCCCCAAGACAG
  GACAGTCTCTAAGGCCATGATCGCCTACTGGACCAACTTTGCCAAAACAGGGGACCCCAA
  CATGGGCGACTCGGCTGTGCCCACACACTGGGAACCCTACACTACGGAAAACAGCGGCTA
  CCTGGAGATCACCAAGAAGATGGGCAGCAGCTCCATGAAGCGGAGCCTGAGAACCAACTT
  CCTGCGCTACTGGACCCTCACCTATCTGGCGCTGCCCACAGTGACCGACCAGGAGGCCAC
  CCCTGTGCCCCCCACAGGGGACTCCGAGGCCACTCCCGTGCCCCCCACGGGTGACTCCGA
  GACCGCCCCCGTGCCGCCCACGGGTGACTCCGGGGCCCCCCCCGTGCCGCCCACGGGTGA
  CTCCGGGGCCCCCCCCGTGCCGCCCACGGGTGACTCCGGGGCCCCCCCCGTGCCGCCCAC
  GGGTGACTCCGGGGCCCCCCCCGTGCCGCCCACGGGTGACTCCGGCGCCCCCCCCGTGCC
  GCCCACGGGTGACGCCGGGCCCCCCCCCGTGCCGCCCACGGGTGACTCCGGCGCCCCCCC
  CGTGCCGCCCACGGGTGACTCCGGGGCCCCCCCCGTGACCCCCACGGGTGACTCCGAGAC
  CGCCCCCGTGCCGCCCACGGGTGACTCCGGGGCCCCCCCTGTGCCCCCCACGGGTGACTC
  TGAGGCTGCCCCTGTGCCCCCCACAGATGACTCCAAGGAAGCTCAGATGCCTGCAGTCAT
  TAGGTTTTAGCGTCCCATGAGCCTTGGTATCAAGAGGCCACAAGAGTGGGACCCCAGGGG
  CTCCCCTCCCATCTTGAGCTCTTCCTGAATAAAGCCTCATACCCCTGAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC042510 unedited
  GTTTAGATATTTGTAATACGACTTTATATAGGGCGGCCGCGNATTCANATCTGGTACCGG
  TCCGGAATTCCCGGGATGATGCTCACCATGGGGCGCCTGCAACTGGTTGTGTTGGGCCTC
  ACCTGCTGCTGGGCAGTGGCGAGTGCCGCGAAGCTGGGCGCCGTGTACACAGAAGGTGGG
  TTCGTGGAAGGCGTCAATAAGAAGCTCGGCCTCCTGGGTGACTCTGTGGACATCTTCAAG
  GGCATCCCCTTCGCAGCTCCCACCAAGGCCCTGGAAAATCCTCAGCCACATCCTGGCTGG
  CAAGGGACCCTGAAGGCCAAGAACTTCAAGAAGAGATGCCTGCAGGCCACCATCAGCCAG
  GACAGCACCTACGGGGATGAAGACTGCCTGTACCTCAACATTTGGGTGCCCCAGGGCAGG
  AAGCAAGTCTCCCGGGACCTGCCCGTTATGATCTGGATCTATGGAGGCGCCTTCCTCATG
  GGGTCCGGCCATGGGGCCAACTTCCTCAACAACTACCTGTATGACGGCGAGGAGATCGCC
  ACACGCGGAAACGTCATCGTGGTCACCTTCACTACCGTGTCGGCCCCCTTGGGTTCCTCA
  GCACTGGGGACGCCAATCTGCCAGGTAACTATGGCCTTCGGGATCAGCACATGGCCATTG
  CTTTGGTTGAGGAAGAAATATCGCGGCCTCGGGGGGGGGACCCCAACAACATCACGCTTC
  TCGGGGAGTCTGCTGGAAGTGCAAGCGTTCTTCTGCAAAACCCTTCCCCCTAAACAAGGG
  CCTCATCCGGCGAGCCATCACCCAAAGGGGCTGGCCCTGAATCCCTGGGTCATCCAGAAA
  AACCCACTTTTTGGGCCAAAAGTGGCTGAAAGGTGGTTGCCTGGGGGGATCCCCCGGATG
  GCCATGGTTTGAGGTTCTGTTCC
  
• Restriction Sites: Please inquire
• ACCN: BC042510
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC042510.1, AAH42510.1
• RefSeq Size: 2316 bp
• Locus ID: 1056
• Cytogenetics: 9q34.13
• Protein Families: Druggable Genome
• Protein Pathways: Glycerolipid metabolism, Metabolic pathways, Steroid biosynthesis
• Gene Summary: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]