ICOS (NM_012092) Human Untagged Clone

CAT#: SC122779

ICOS (untagged)-Human inducible T-cell co-stimulator (ICOS)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ICOS
• Synonyms: AILIM; CD278; CVID1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012092 edited
  CTGAACGCGAGGACTGTTAACTGTTTCTGGCAAACATGAAGTCAGGCCTCTGGTATTTCT
  TTCTCTTCTGCTTGCGCATTAAAGTTTTAACAGGAGAAATCAATGGTTCTGCCAATTATG
  AGATGTTTATATTTCACAACGGAGGTGTACAAATTTTATGCAAATATCCTGACATTGTCC
  AGCAATTTAAAATGCAGTTGCTGAAAGGGGGGCAAATACTCTGCGATCTCACTAAGACAA
  AAGGAAGTGGAAACACAGTGTCCATTAAGAGTCTGAAATTCTGCCATTCTCAGTTATCCA
  ACAACAGTGTCTCTTTTTTTCTATACAACTTGGACCATTCTCATGCCAACTATTACTTCT
  GCAACCTATCAATTTTTGATCCTCCTCCTTTTAAAGTAACTCTTACAGGAGGATATTTGC
  ATATTTATGAATCACAACTTTGTTGCCAGCTGAAGTTCTGGTTACCCATAGGATGTGCAG
  CCTTTGTTGTAGTCTGCATTTTGGGATGCATACTTATTTGTTGGCTTACAAAAAAGATGT
  GACCCTATAATATGGAACTCTGGCACCCAGGCATGAAGCACGTTGGCCAGTTTTCCTCAA
  CTTGAAGTGCAAGATTCTCTTATTTCCGGGACCACGGAGAGTCTGACTTAACTACATACA
  TCTTCTGCTGGTGTTTTGTTCAATCTGGAAGAATGACTGTATCAGTCAATGGGGATTTTA
  ACAGACTGCCTTGGTACTGCCGAGTCCTCTCAAAACAAACACCCTCTTGCAACCAGCTTT
  GGAGAAAGCCCAGCTCCTGTGTGCTCACTGGGAGTGGAATCCCTGTCTCCACATCTGCTC
  CTAGCAGTGCATCAGCCAGTAAAACAAACACATTTACAAGAAAAATGTTTTAAAGATGCC
  AGGGGTACTGAATCTGCAAAGCAAATGAGCAGCCAAGGACCAGCATCTGTCCGCATTTCA
  CTATCATACTACCTCTTCTTTCTGTAGGGATGAGAATTCCTCTTTTAATCAGTCAAGGGA
  GATGCTTCAAAGCTGGAGCTATTTTATTTCTGAGATGTTGATGTGAACTGTACATTAGTA
  CATACTCAGTACTCTCCTTCAATTGCTGAACCCCAGTTGACCATTTTACCAAGACTTTAG
  ATGCTTTCTTGTGCCCTCAATTTTCTTTTTAAAAATACTTCTACATGACTGCTTGACAGC
  CCAACAGCCACTCTCAATAGAGAGCTATGTCTTACATTCTTTCCTCTGCTGCTCAATAGT
  TTTATATATCTATGCATACATATATACACACATATGTATATAAAATTCATAATGAATATA
  TTTGCCTATATTCTCCCTACAAGAATATTTTTGCTCCAGAAAGACATGTTCTTTTCTCAA
  ATTCAGTTAAAATGGTTTACTTTGTTCAAGTTAGTGGTAGGAAACATTGCCCGGAATTGA
  AAGCAAATTTATTTTATTATCCTATTTTCTACCATTATCTATGTTTTCATGGTGCTATTA
  ATTACAAGTTTAGTTCTTTTTGTAGATCATATTAAAATTGCAAACAAAATCATCTTTAAT
  GGGCCAGCATTCTCATGGGGTAGAGCAGAATATTCATTTAGCCTGAAAGCTGCAGTTACT
  ATAGGTTGCTGTCAGACTATACCCATGGTGCCTCTGGGCTTGACAGGTCAAAATGGTCCC
  CATCAGCCTGGAGCAGCCCTCCAGACCTGGGTGGAATTCCAGGGTTGAGAGACTCCCCTG
  AGCCAGAGGCCACTAGGTATTCTTGCTCCCAGAGGCTGAAGTCACCCTGGGAATCACAGT
  GGTCTACCTGCATTCATAATTCCAGGATCTGTGAAGAGCACATATGTGTCAGGGCACAAT
  TCCCTCTCATAAAAACCACACAGCCTGGAAATTGGCCCTGGCCCTTCAAGATAGCCTTCT
  TTAGAATATGATTTGGCTAGAAAGATTCTTAAATATGTGGAATATGATTATTCTTAGCTG
  GAATATTTTCTCTACTTCCTGTCTGCATGCCCAAGGCTTCTGAAGCAGCCAATGTCGATG
  CAACAACATTTGTAACTTTAGGTAAACTGGGATTATGTTGTAGTTTAACATTTTGTAACT
  GTGTGCTTATAGTTTACAAGTGAGACCCGATATGTCATTATGCATACTTATATTATCTTA
  AGCATGTGTAATGCTGGATGTGTACAGTACAGTACTGAACTTGTAATTTGAATCTAGTAT
  GGTGTTCTGTTTTCAGCTGACTTGGACAACCTGACTGGCTTTGCACAGGTGTTCCCTGAG
  TTGTTTGCAGGTTTCTGTGTGTGGGGTGGGGTATGGGGAGGAGAACCTTCATGGTGGCCC
  ACCTGGCCTGGTTGTCCAAGCTGTGCCTCGACACATCCTCATCCCCAGCATGGGACACCT
  CAAGATGAATAATAATTCACAAAATTTCTGTGAAATCAAATCCAGTTTTAAGAGGAGCCA
  CTTATCAAAGAGATTTTAACAGTAGTAAGAAGGCAAAGAATAAACATTTGATATTCAGCA
  ACTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012092 unedited
  ATNCACTATTAGGGCGGCCCGCGNATATCATATCTGGTACCGGTCCCGGAATTCCCGGGA
  TCTGAACGCGAGGACTGTTAACTGTTTCCGGCAAACACGAAGCCAGGCCCTCTGGTATTT
  CTCTTCTCTCTCTGCTTGCGCATTAAAGTCTTAACAGGAGAAACCAAGGTTCCGCCAACA
  CGAGATGTTTATATTCCCAACGGAGGTGTTACAAACCTTATGCAAATATCCTGACATTGT
  CCAGCAATCTAAAAGGCAGTTGCCGAAAGGGGGGCAAAAACTCTGCCGTCCCACCAAGAC
  CAAAGGGAAGTGGAAACACAGTGTCCATTAAGAAGTCCTGAAATTCTGCCATTCTCAGTT
  ATCCAACAACAGTGTCTCTTTTTTTCTATACAACTTGGACCATTCTCATGCCAACTATTA
  CTTCTGCAACCTATCAATTTTTGATCCTCCTCCTTTTAAAGTAACTCTTACAGGAGGATA
  TTTGCATATTTATGAATCACAACTTTGTTGCCAGCTGAAGTTCTGGTTACCCATAGGATG
  TGCAGCCTTTGTTGTAGTCTGCATTTTGGGATGCATACTTATTTGTTGGCTTACAAAAAA
  GATGTGACCCTATAATATGGAACTCTGGCACCCAGGCATGAAGCACGTTGGCCAGTTTTC
  CTCAACTTGAAGTGCAAGATTCTCTTATTTCCGGGACCACGGAGAGTCTGACTTAACTAC
  ATACATCTTCTGCTGGTGTTTTGTTCAATCTGGAAGAATGACTGTATCAGTCAATGGGGA
  TTTTAACAGACTGCCTTGGTACTGCCGAGTCCTCTCAAACANACACCCTCTTGNCACCAG
  CTTTGGAGAAACCCAGCTCCTGTGTGCTCACTGGGAGTT
  
• Restriction Sites: Please inquire
• ACCN: NM_012092
• Insert Size: 2580 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012092.2, NP_036224.1
• RefSeq Size: 2620 bp
• RefSeq ORF: 600 bp
• Locus ID: 29851
• UniProt ID: Q9Y6W8
• Cytogenetics: 2q33.2
• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway
• Gene Summary: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]