ITPKB (BC015009) Human Untagged Clone

CAT#: SC122241

ITPKB (untagged)-Human inositol 1,4,5-trisphosphate 3-kinase B (cDNA clone MGC:23636 IMAGE:4862726), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITPKB
• Synonyms: 1D-myo-inositol-trisphosphate 3-kinase B; inositol 1,4,5-trisphosphate 3-kinase B; IP3 3-kinase; IP3K; IP3K-B; IP3KB; OTTHUMP00000035705; PIG37; proliferation-inducing protein 37
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC015009 edited
  CCTCTTTTTTGTCTTCCATAGCTTGTGAGAAAATAATTTCTGAGCATTTTTACTTTTAAA
  GCCATCTCGTCCCTACGAGGTTTGCGCCTCTGGGCATGTAGTCTACACAGGACCTGAGAA
  TCTGAGAAACTGCAGCCGCACGGTTGTTTATGGAGCTTTGGGCGGGGGCTGAGCCCGCGG
  TCGTGCCCCCAGCCCGCTGCCCAGGCCATGCCGCCCCATCTGCGCGCGGAGCCGCGGCTG
  CCGGGCCTCCGGGGCTGAGCCGGGAGCGCCGGGAGGAGGAGGCGCCGGCGGCGGAGCAGG
  AGCGGGAGCCGCGGCGGCGGGCAGCGCGGGACCCAGTACTATGGCTGTGTACTGCTATGC
  GCTCAATAGCCTGGTGATCATGAATAGCGCCAACGAGATGAAGAGCGGCGGCGGCCCGGG
  GCCCAGTGGCAGCGAGACGCCCCCGCCCCCGAGGAGGGCAGTGCTGAGCCCCGGCAGCGT
  TTTCAGCCCCGGGAGAGGCGCCTCTTTCCTCTTCCCCCCAGCCGAGTCGCTGTCCCCCGA
  GGAGCCCCGGAGCCCCGGGGGCTGGCGGAGCGGCCGGCGCAGGCTGAATAGTAGCAGCGG
  CAGTGGCAGCGGCAGCAGCGGCAGTAGCGTGAGCAGCCCAAGTTGGGCTGGTCGCCTGCG
  AGGGGACCGGCAGCAGGTGGTGGCAGCCGGTACCCTCTCCCCGCCAGGGCCGGAGGAGGC
  CAAGAGGAAGCTGCGGATCTTGCAGCGCGAGTTGCAGAACGTGCAGGTGAACCAGAAAGT
  GGGCATGTTTGAGGCGCACATCCAGGCACAGAGCTCCGCCATTCAAGCGCCCCGCAGCCC
  GCGTTTGGGCAGGGCTCACTCGCCCTCCCCGTGCCCCTTCCGCAGCAGCAGTCAGCCCCC
  TGGAAGGGTCCTGGTTCAGGGCGCCCGGAGCGAGGAACGGAGGACAAAGTCCTGGGGGGA
  GCAATGTCCAGAGACTTCAGGAACCGACTCCGGGAGGAAAGGAGGGCCCAGCCTATGCTC
  CTCGCAGGTGAAGAAAGGAATGCCACCTCTTCCCGGCCGGGCTGCCCCTACAGGATCAGA
  GGCTCAGGGTCCATCCGCTTTTGTAAGGATGGAGAAGGGTATCCCTGCCAGTCCCCGCTG
  TGGCTCACCCACAGCTATGGAAATTGACAAAAGGGGCTCTCCTACCCCGGGAACTCGGAG
  CTGCCTAGCTCCCTCATTGGGGCTGTTCGGAGCTAGCTTAACGATGGCCACGGAAGTGGC
  AGCGAGAGTTACATCCACTGGGCCACACCGTCCACAGGATCTTGCCCTCACTGAGCCGTC
  TGGGAGAGCCCGTGAGCTTGAGGACCTGCAGCCCCCAGAGGCCCTGGTGGAGAGGCAGGG
  GCAGTTTCTGGGCAGTGAGACAAGCCCAGCCCCAGAAAGGGGCGGGCCCCGCGATGGAGA
  ACCCCCTGGGAAGATGGGGAAAGGATATCTGCCCTGTGGCATGCCGGGCTCTGGGGAGCC
  TGAAGTGGGCAAAAGGCCAGAGGAGACGACTGTGAGCGTGCAAAGCGCAGAGTCCTCTGA
  TGCCCTGAGCTGGTCCAGGCTGCCCAGGGCCCTGGCCTCCGTAGGCCCTGAGGAGGCCCG
  AAGTGGGGCCCCCGTGGGCGGGGGGCGTTGGCAGCTCTCCGACAGAGTGGAGGGAGGGTC
  CCCAACGCTGGGCTTGCTTGGGGGCAGCCCCTCAGCACAGCCGGGGACCGGGAATGTGGA
  GGCGGGAATTCCTTCTGGCAGAATGCTGGAGCCTTTGCCCTGTTGGGACGCTGCGAAAGA
  TCTGAAAGAACCTCAGTGCCCTCCTGGGGACAGGGTGGGTGTGCAGCCTGGGAACTCCAG
  GGTTTGGCAGGGCACCATGGAGAAAGCCGGTTTGGCTTGGACGCGTGGCACAGGGGTGCA
  ATCAGAGGGGACTTGGGAAAGCCAGCGGCAGGACAGTGATGCCCTCCCAAGTCCGGAGCT
  GCTACCCCAAGATCAGGACAAGCCTTTCCTGAGGAAGGCCTGCAGCCCCAGCAACATACC
  TGCTGTCATCATTACAGACATGGGCACCCAGGAGGATGGGGCCTTGGAGGAGACGCAGGG
  AAGCCCTCGGGGCAACCTGCCCCTGAGGAAACTGTCCTCTTCCTCGGCCTCCTCCACGGG
  CTTCTCCTCATCCTACGAAGACTCAGAGGAGGACATCTCCAGTGACCCTGAGCGCACCCT
  GGACCCCAACTCAGCCTTCCTGCATACCCTGGACCAGCAGAAACCTAGAGTGTGACTTCT
  TGGGAAGTGTTCCCCTCAGTGGTACTGCTGGGGCAACGTCCAATACCAAGAATGATGTAT
  AGCATATTTCATCTTCCTACACTACTCTCTGGAAAGACTGAGCCAATTACGGGGTCATCT
  GTAAAGTCTAAGTGCTGCAGTTTCCCTACGACCATTGGATTTTGTTTGTAGTTTGATATT
  GTCTTACTGTCCCTTGAAGTTGTAATTTGTAATTCTTTAGTTTTCAAGAGGGACTCTACA
  TGTTTCCTTGTGATGATGGCCTTGAGTTACTCATGTGTACACTGCCTATTTATCCCCATT
  GAGCCCCCACTGCCCGAACATGTTGATGGCATTTTATATAGTAAGCTGTCAGTTACTTAA
  TGTACAAATATTCTTCCATTCCATGTTTTTCTCTTAAAATTTTACTTTATTGGCCAGGCG
  CAGTGGCTCACATCTGTAATCCCAGCACTTTAGGAGGCCAAGGCGGGCGGATCACCTGAG
  GTCAAGAGATTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAAATAC
  AAAAATTAGCCAGGTGTAGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGC
  AGGAGAATTGCTTGAACCTGAGAGGCGGAGGTTGCGGTGAGCCGAGATAGCACCACTGCA
  CTCCAGCCTGGGCGAAAGAGCTAAACTCCATCTCAAAAATAAATAAATAAATAAAAAAAA
  AAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC015009 unedited
  NNAAGTACAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCTCTT
  TTTTGTCTTCCATAGCTTGTGAGAAAATAATTTCTGAGCATTTTTACTTTTAAAGCCATC
  TCGTCCCTACGAGGTTTGCGCCTCTGGGCATGTAGTCTACACAGGACCTGAGAATCTGAG
  AAACTGCAGCCGCACGGTTGTTTATGGAGCTTTGGGCGGGGGCTGAGCCCGCGGTCGTGC
  CCCCAGCCCGCTGCCCAGGCCATGCCGCCCCATCTGCGCGCGGAGCCGCGGCTGCCGGGC
  CTCCGGGGCTGAGCCGGGAGCGCCGGGAGGAGGAGGCGCCGGCGGCGGAGCAGGAGCGGG
  AGCCGCGGCGGCGGGCAGCGCGGGACCCAGTACTATGGCTGTGTACTGCTATGCGCTCAA
  TAGCCTGGTGATCATGAATAGCGCCAACGAGATGAAGAGCGGCGGCGGCCCGGGGCCCAG
  TGGCAGCGAGACGCCCCCGCCCCCGAGGAGGGCAGTGCTGAGCCCCGGCAGCGTTTTCAG
  CCCCGGGAGAGGCGCCTCTTTCCTCTTCCCCCCAGCCGAGTCGCTGTCCCCCGAGGAGCC
  CCGGAGCCCCGGGGGCTGGCGGAGCGGCCGGCGCAGGCTGAATAGTAGCAGCGGCAGTGG
  CAGCGGCAGCAGCGGCAGTAGCGTGAGCAGCCCAAGTTGGGCTGGTCGCCTGCGAGGGGA
  CCGGCAGCAGGTGGTGGCAGCCGGTACCCTCTCCCCGCCAGGGCCGGAGGAGGCCCAAGA
  GAAGCTGCGGATCTTGCAGCGCGAGTTGCAGAACGTGCAGGTGAACCAGAAAGTGGGCAT
  GTTTTGAGCGCACATCCAGGCACAGAGCTCCGCCATTTCAGCGCCCCGCAGCCCGC
  
• Restriction Sites: Please inquire
• ACCN: BC015009
• Insert Size: 3010 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC015009.1, AAH15009.1
• RefSeq Size: 3010 bp
• Locus ID: 3707
• Cytogenetics: 1q42.12
• Protein Families: Druggable Genome
• Protein Pathways: Calcium signaling pathway, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]