GDF7 (NM_182828) Human Untagged Clone

CAT#: SC122219

GDF7 (untagged)-Human growth differentiation factor 7 (GDF7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GDF7
• Synonyms: BMP12
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_182828, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCTGAGCGCCGCCGCCGCGCTGTGCCTTTGGCTGCTGAGCGCCTGCCGCCCCCGCGACGGGCTGG
  AAGCGGCCGCCGTGCTGCGAGCGGCGGGGGCTGGGCCGGTCCGGAGCCCAGGGGGCGGCGGCGGCGGCGG
  CGGCGGCGGGCGGACTCTTGCCCAGGCTGCGGGCGCCGCGGCTGTCCCGGCCGCCGCGGTTCCCCGGGCC
  CGCGCCGCGCGCCGCGCCGCGGGCTCCGGCTTCAGGAACGGCTCGGTGGTGCCGCACCACTTCATGATGT
  CGCTTTACCGGAGCCTGGCCGGGAGGGCTCCGGCCGGGGCAGCCGCTGTCTCCGCCTCGGGCCATGGTCG
  CGCGGACACGATCACCGGCTTCACAGACCAGGCGACCCAAGACGAATCGGCAGCCGAAACAGGCCAGAGC
  TTCCTGTTCGACGTGTCCAGCCTTAACGACGCAGACGAGGTGGTGGGTGCCGAGCTGCGCGTGCTGCGCC
  GGGGATCTCCAGAGTCGGGCCCAGGCAGCTGGACTTCTCCGCCGTTGCTGCTGCTGTCCACGTGCCCGGG
  CGCCGCCCGAGCGCCACGCCTGCTGTACTCGCGGGCAGCTGAGCCCCTAGTCGGTCAGCGCTGGGAGGCG
  TTCGACGTGGCGGACGCCATGAGGCGCCACCGTCGTGAACCGCGCCCCCCCCGCGCGTTCTGCCTCTTGC
  TGCGCGCAGTGGCAGGCCCGGTGCCGAGCCCGTTGGCACTGCGGCGGCTGGGCTTCGGCTGGCCGGGCGG
  AGGGGGCTCTGCGGCAGAGGAGCGCGCGGTGCTAGTCGTCTCCTCCCGCACGCAGAGGAAAGAGAGCTTA
  TTCCGGGAGATCCGCGCCCAGGCCCGCGCGCTCGGGGCCGCTCTGGCCTCAGAGCCGCTGCCCGACCCAG
  GAACCGGCACCGCGTCGCCAAGGGCAGTCATTGGCGGCCGCAGACGGAGGAGGACGGCGTTGGCCGGGAC
  GCGGACAGCGCAGGGCAGCGGCGGGGGCGCGGGCCGGGGCCACGGGCGCAGGGGCCGGAGCCGCTGCAGC
  CGCAAGCCGTTGCACGTGGACTTCAAGGAGCTCGGCTGGGACGACTGGATCATCGCGCCGCTGGACTACG
  AGGCGTACCACTGCGAGGGCCTTTGCGACTTCCCTTTGCGTTCGCACCTCGAGCCCACCAACCATGCCAT
  CATTCAGACGCTGCTCAACTCCATGGCACCAGACGCGGCGCCGGCCTCCTGCTGTGTGCCAGCGCGCCTC
  AGCCCCATCAGCATCCTCTACATCGACGCCGCCAACAACGTTGTCTACAAGCAATACGAGGACATGGTGG
  TGGAGGCCTGCGGCTGCAGGTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_182828 unedited
  TAGCGTTCNTTTTTGTAATACGACTTACTATAGGGGCGGCCGCGTATTCGGCACGAGGCA
  CACTTTCCCCCATTATTAAACACTATGTTCAAAAGGCGCCGGGGGACTTCCCGGAGCCAC
  GGAGCCCGCGCCGCCCGCCCGCCCGGCCCACGGAGCCCATGGACCTGAGCGCCGCCGCCG
  CGCTGTGCCTTTGGCTGCTGAGCGCCTGCCGCCCCCGCGACGGGCTGGAAGCGGCCGCCG
  TGCTGCGAGCGGCGGGGGCTGGGCCGGTCCGGAGCCCAGGGGGCGGCGGCGGCGGCGGCG
  GCGGCGGCGGCGGCGGGCGGACTCTTGCCCATGCTGCGGGCGCCGCGGCTGTTCCGGCCG
  CCGTGGTTTCCTGGGACCTCCCTTCCTTCTGCGGCTCGGCGGTGTTGTTGGGGTCTCTCA
  ACTTGGGTTGCGGTCTCTTAGGCGCCTCGTTTGTTTTGGGTCGCATCTGGATCTTGTGCC
  GTCTGTGCGTTTCATAGTTTCCTGTTTCGCTGCTTGCGGATGTGGGTCGTTTTTGCGTTG
  TCTTCCGTGTTTCTTTTTTTTCTGTCTGTGTCCGTGCTGTTCTGTATACGTTGCTGTTGT
  TGATCCTTCGTGTTTATAATTTGCTAGTTGCCGCGCTGAGTCTTTTCGCCGAACTAGGAC
  GTCATGAGTAGTTGAGCGGTCCTTACTGGTCGTTCGCGAGGTGTTGATTTCGTTCTATGA
  GCGTTCGCTATTGTTAACGTGGCCGTATATGGTCTGTTCCAATGGTCTTTTTGTGACATG
  TGTGGTGGCCAGATCCGTTTCTCTGGTTCTGACATCTCTCTTAGATGCGCTCTCTCGTGC
  TGTTAATGTATGTCTCTCGACTGGTGTGTTTTATCGTCCTCGCTTCGGTTGTAAATTGCG
  TAGTTGGGGTGTGGGTAGTATTATGGTTTGTGTCCACCTGATTACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_182828 unedited
  GAAAGGACGCTCTGGCCTGTTTCGGCTGCCGATTCGTCTTGGGTCGCCTGGTCTGTGAAG
  CCGGTGATCGTGTCCGCGCGACCATGGCCCGAGGCGGAGACAGCGGCTGCCCCGGCCGGA
  GCCCTCCCGGCCAGGCTCCGGTAAAGCGACATCATGAAGTGGTGCGGCACCACCGAGCCG
  TTCCTGAAGCCGGAGCCCGCGGCGCGGCGCGCGGCGCGGGCCCGGGGAACCGCGGCGGCC
  GGGACAACCCGCGGCGCCCGCAGCCTGGGCAAGAAGTCCGCCCGCCGCCGCCGCCGCCGC
  CGCCGCCGCCGGCGGCCCCCTGGGCTCCGGACCGGCCCAACCCCCGGCGGTCGAAGCACC
  GCGGCCGCTTCCAGCCCGTCGCGGGGGCGGCAGGCGCTCAGCAGCCAAAGGCACAGCGCG
  GCGGCGGCGCTCAGGTCCATGGGCTCCGTTGGGCCGGCGGGCGGGCGGCGCGGGCTCCGT
  GGCTCCGGGAAGTCCCCCGGCGCCTTTTGAACATAGTGTTTAATAATGGGGGAAGTGTGC
  CTCGTGCCGAATTCGCGGCCGCCCTATAGTGAGTCGTATTACAAAATTCTGACGGTTCAC
  TAAACGAGCTCTGCTTATATAGACCTCCCACCGTACACGCCTACCGCCCATTTGCGTCAA
  CGGGGCGGGGTTATTACGACATTTTGGAAAGTCCCGTTGATTTTGTGCCAAAACAACTCC
  ATTGACGTCATGGGTGGAGACTGGGAATCCCCTGAATAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_182828
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_182828.2, NP_878248.2
• RefSeq Size: 1994 bp
• RefSeq ORF: 1353 bp
• Locus ID: 151449
• UniProt ID: Q7Z4P5
• Cytogenetics: 2p24.1
• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
• Protein Pathways: TGF-beta signaling pathway
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]