IL3RB (CSF2RB) (NM_000395) Human Untagged Clone

CAT#: SC119900

CSF2RB (untagged)-Human colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (CSF2RB)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL3RB
• Synonyms: betaGMR; CD131; CDw131; IL3RB; IL5RB; SMDP5
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000395 edited
  CTCCCACCACACAGAGGCCTGGAGGAGGCAGAGGCCAGGAGGGAGAGGTCCCAAGAGCCT
  GTGAAATGGGTCTGGCCTGGCTCCCAGCTGGGCAGGAACACAGGACTTCAGGATACTAAG
  GACCCTGTCATGCCCATGGCCAGCACCCACCAGTGCTGGTGCCTGCCTGTCCAGAGCTGA
  CCAGGGAGATGGTGCTGGCCCAGGGGCTGCTCTCCATGGCCCTGCTGGCCCTGTGCTGGG
  AGCGCAGCCTGGCAGGGGCAGAAGAAACCATCCCGCTGCAGACCCTGCGCTGCTACAACG
  ACTACACCAGCCACATCACCTGCAGGTGGGCAGACACCCAGGATGCCCAGCGGCTCGTCA
  ACGTGACCCTCATTCGCCGGGTGAATGAGGACCTCCTGGAGCCAGTGTCCTGTGACCTCA
  GTGATGACATGCCCTGGTCAGCCTGCCCCCATCCCCGCTGCGTGCCCAGGAGATGTGTCA
  TTCCCTGCCAGAGTTTTGTCGTCACTGACGTTGACTACTTCTCATTCCAACCAGACAGGC
  CTCTGGGCACCCGGCTCACCGTCACTCTGACCCAGCATGTCCAGCCTCCTGAGCCCAGGG
  ACCTGCAGATCAGCACCGACCAGGACCACTTCCTGCTGACCTGGAGTGTGGCCCTTGGGA
  GTCCCCAGAGCCACTGGTTGTCCCCAGGGGATCTGGAGTTTGAGGTGGTCTACAAGCGGC
  TTCAGGACTCTTGGGAGGACGCAGCCATCCTCCTCTCCAACACCTCCCAGGCCACCCTGG
  GGCCAGAGCACCTCATGCCCAGCAGCACCTACGTGGCCCGAGTACGGACCCGCCTGGCCC
  CAGGTTCTCGGCTCTCAGGACGTCCCAGCAAGTGGAGCCCAGAGGTTTGCTGGGACTCCC
  AGCCAGGGGATGAGGCCCAGCCCCAGAACCTGGAGTGCTTCTTTGACGGGGCCGCCGTGC
  TCAGCTGCTCCTGGGAGGTGAGGAAGGAGGTGGCCAGCTCGGTCTCCTTTGGCCTATTCT
  ACAAGCCCAGCCCAGATGCAGGGGAGGAAGAGTGCTCCCCAGTGCTGAGGGAGGGGCTCG
  GCAGCCTCCACACCAGGCACCACTGCCAGATTCCCGTGCCCGACCCCGCGACCCACGGCC
  AATACATCGTCTCTGTTCAGCCAAGGAGGGCAGAGAAACACATAAAGAGCTCAGTGAACA
  TCCAGATGGCCCCTCCATCCCTCAACGTGACCAAGGATGGAGACAGCTACAGCCTGCGCT
  GGGAAACAATGAAAATGCGATACGAACACATAGACCACACATTTGAGATCCAGTACAGGA
  AAGACACGGCCACGTGGAAGGACAGCAAGACCGAGACCCTCCAGAACGCCCACAGCATGG
  CCCTGCCAGCCCTGGAGCCCTCCACCAGGTACTGGGCCAGGGTGAGGGTCAGGACCTCCC
  GCACCGGCTACAACGGGATCTGGAGTGAGTGGAGTGAGGCGCGCTCCTGGGACACCGAGT
  CGGTGCTGCCTATGTGGGTGCTGGCCCTCATCGTGATCTTCCTCACCATCGCTGTGCTCC
  TGGCCCTCCGCTTCTGTGGCATCTACGGGTACAGGCTGCGCAGAAAGTGGGAGGAGAAGA
  TCCCCAACCCCAGCAAGAGCCACCTGTTCCAGAACGGGAGCGCAGAGCTTTGGCCCCCAG
  GCAGCATGTCGGCCTTCACTAGCGGGAGTCCCCCACACCAGGGGCCGTGGGGCAGCCGCT
  TCCCTGAGCTGGAGGGGGTGTTCCCTGTAGGATTCGGGGACAGCGAGGTGTCACCTCTCA
  CCATAGAGGACCCCAAGCATGTCTGTGATCCACCATCTGGGCCTGACACGACTCCAGCTG
  CCTCAGATCTACCCACAGAGCAGCCCCCCAGCCCCCAGCCAGGCCCGCCTGCCGCCTCCC
  ACACACCTGAGAAACAGGCTTCCAGCTTTGACTTCAATGGGCCCTACCTGGGGCCGCCCC
  ACAGCCGCTCCCTACCTGACATCCTGGGCCAGCCGGAGCCCCCACAGGAGGGTGGGAGCC
  AGAAGTCCCCACCTCCAGGGTCCCTGGAGTACCTGTGTCTGCCTGCTGGGGGGCAGGTGC
  AACTGGTCCCTCTGGCCCAGGCGATGGGACCGGGACAGGCCGTGGAAGTGGAGAGAAGGC
  CGAGCCAGGGGGCTGCAGGGAGTCCCTCCCTGGAGTCCGGGGGAGGCCCTGCCCCTCCTG
  CTCTTGGGCCAAGGGTGGGAGGACAGGACCAAAAGGACAGCCCTGTGGCTATACCCATGA
  GCTCTGGGGACACTGAGGACCCTGGAGTGGCCTCTGGTTATGTCTCCTCTGCAGACCTGG
  TATTCACCCCAAACTCAGGGGCCTCGTCTGTCTCCCTAGTTCCCTCTCTGGGCCTCCCCT
  CAGACCAGACCCCCAGCTTATGTCCTGGGCTGGCCAGTGGACCCCCTGGAGCCCCAGGCC
  CTGTGAAGTCAGGGTTTGAGGGCTATGTGGAGCTCCCTCCAATTGAGGGCCGGTCCCCCA
  GGTCACCAAGGAACAATCCTGTCCCCCCTGAGGCCAAAAGCCCTGTCCTGAACCCAGGGG
  AACGCCCGGCAGATGTGTCCCCAACATCCCCACAGCCCGAGGGCCTCCTTGTCCTGCAGC
  AAGTGGGCGACTATTGCTTCCTCCCCGGCCTGGGGCCCGGCCCTCTCTCGCTCCGGAGTA
  AACCTTCTTCCCCGGGACCCGGTCCTGAGATCAAGAACCTAGACCAGGCTTTTCAAGTCA
  AGAAGCCCCCAGGCCAGGCTGTGCCCCAGGTGCCCGTCATTCAGCTCTTCAAAGCCCTGA
  AGCAGCAGGACTACCTGTCTCTGCCCCCTTGGGAGGTCAACAAGCCTGGGGAGGTGTGTT
  GAGACCCCCAGGCCTAGACAGGCAAGGGGATGGAGAGGGCTTGCCTTCCCTCCCGCCTGA
  CCTTCCTCAGTCATTTCTGCAAAGCCAAGGGGCAGCCTCCTGTCAAGGTAGCTAGAGGCC
  TGGGAAAGGAGATAGCCTTGCTCCGGCCCCCTTGACCTTCAGCAAATCACTTCTCTCCCT
  GCGCTCACACAGACACACACACACACACGTACATGCACACATTTTTCCTGTCAGGTTAAC
  TTATTTGTAGGTTCTGCATTATTAGAACTTTCTAGATATACTCATTCCATCTCCCCCTCA
  TTTTTTTAATCAGGTTTCCTTGCTTTTGCCATTTTTCTTCCTTCTTTTTTCACTGATTTA
  TTATGAGAGTGGGGCTGAGGTCTGAGCTGAGCCTTATCAGACTGAGATGCAGCTGGTTGT
  GTTGAGGACTTGTGTGGGCTGCCTGTCCCCGGCAGTCGCTGATGCACATGACATGATTCT
  CATCTGGGTGCAGAGGTGGGAGGCACCAGGTGGGCACCCGTGGGGGTTAGGGCTTGGAAG
  AGTGGCACAGGACTGGGCACGCTCAGTGAGGCTCAGGGAATTCAGACTAGCCTCGATTGT
  CACTCCGAGAAATGGGCATGGTATTGGGGGTCGGGGGGGCGGTGCAAGGGACGCACATGA
  GAGACTGTTTGGGAGCTTCTGGGGAGCCCTGCTAGTTGTCTCAGTGATGTCTGTGGGACC
  TCCAGTCCCTTGAGACCCCACGTCATGTAGAGAAGTTAACGGCCCAAGTGGTGGGCAGGC
  TGGCGGGACCTGGGGAACATCAGGAGAGGAGTCCAGAGCCCACGTCTACTGCGGAAAXXX
  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTTACTGTCAGATTTACAAAG
  GTCCTCCCATTGCAAAGCAGTGTTTGTCCTAATTTATATATTGTTTTTCTAGTTCATTTT
  GTGTTTCCAACTTTTCATGTAAAATTTTAATTATTTTTGAATGTGTGGATGTGAGACTGA
  GGTGCCTTTTGGTACTGAAATTCTTTTTCCATGTACCTGAAGTGTTACTTTTGTGATATA
  GGAAATCCTTGTATATATACTTTATTGGTCCCTAGGCTTCCTATTTTGTTACCTTGCTTT
  CTCTATGGCATCCACCATTTTGATTGTTCTACTTTTATGATATGTTTTCATAAGTGGTTA
  AGCAAGTATTCTCGTTACTTTTGCTCTTAAATCCCTATTCATTACAGCAATGTTGGTGGT
  CAAAGAAAATGATAAACAACTTGAATGTTCAATGGTCCTGAAATACATAACAACATTTTA
  GTACATTGTAAAGTAGAATCCTCTGTTCATAATGAACAAGATGAACCAATGTGGATTAGA
  AAGAAGTCCGAGATATTAATTCCAAAATATCCAGACATTGTTAAAGGGAAAAAATTGCAA
  TAAAATATTTGTAAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000395 unedited
  TATATCCCCCGCCCGTTGNCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAA
  GCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCG
  CGAATTCGGCACGAGGCTCCCACCACACAGAGGCCTGGAGGAGGCAGAGGCCAGGAGGGA
  GAGGTCCCAAGAGCCTGTGAAATGGGTCTGGCCTGGCTCCCAGCTGGGCAGGAACACAGG
  ACTTCAGGATACTAAGGACCCTGTCATGCCCATGGCCAGCACCCACCAGTGCTGGTGCCT
  GCCTGTCCAGAGCTGACCAGGGAGATGGTGCTGGCCCAGGGGCTGCTCTCCATGGCCCTG
  CTGGCCCTGTGCTGGGAGCGCAGCCTGGCAGGGGCAGAAGAAACCATCCCGCTGCAGACC
  CTGCGCTGCTACAACGACTACACCAGCCACATCACCTGCAGGTGGGCAGACACCCAGGAT
  GCCCAGCGGCTCGTCAACGTGACCCTCATTCGCCGGGTGAATGAGGACCTCCTGGAGCCA
  GTGTCCTGTGACCTCAGTGATGACATGCCCTGGTCAGCCTGCCCCCATCCCCGCTGCGTG
  CCCAGGAGATGTGTCATTCCCTGCCAGAGTTTTGTCGTCACTGACGTTGACTACTTCTCA
  TTCCAACCAGACAGGCCTCTGGGCACCCGGCTCACCGTCACTCTGACCCAGCATGTCCAG
  CCTCCTGAGCTCAGNGACCTGCAGATCAGCACCGACCAGAACCACTTCCTGCTGACCTGG
  AGTGTGGCCCTTGNGAGTCCTCAGAGCCACTGGTTGTCCTCTAGGGATCTGGAGTTTGAG
  GTGATCTACAAGCGGCTACAGGACTCTTGNGAGGACGCAGNCATNCTCCTATCTACACCT
  TTCTAGCCCTCTGNNGCCAGAGCACTCATGTCCACAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000395 unedited
  GGCCTACTATGTACCGTCGGCCGCTTTTAGGATCGATTTTTTTTTTTTTTTTTTGTTACA
  AATATTTTATTGCAATTTTTTCCCTTTAACAATGTCTGGATATTTTGGAATTAATATCTC
  GGACTTCTTTCTAATCCACATTGGTTCATCTTGTTCATTATGAACAGAGGATTCTACTTT
  ACAATGTACTAAAATGTTGTTATGTATTTCAAGACCATTGAACATTCAAGTTGTTTATCA
  TTTTCTTTGACCACCAACATTGCTGTAATGAATAGGGATTTAAGAGCAAAAGTAACGAGA
  ATACTTGCTTAACCACTTATGAAAACATATCATAAAAGTAGAACAATCAAAATGGTGGAT
  GCCATAGAGAAAGCAAGGTAACAAAATAGGAAGCCTAGGGACCAATAAAGTATATATACA
  AGGATTTCCTATATCACAAAAGTAACACTTCAGGTACATGGAAAAAGAATTTCAGTACCA
  AAAGGCACCTCAGTCTCACATCCACACATTCAAAAATAATTAAAATTTTACATGAAAAGT
  TGGAAACACAAAATGAACTAGAAAAACAATATATAAATTATGACAAACACTGCTTTGCAA
  TGGGAGGACCTTTGTAAATCTGACAGTTAAAGTGAAAAAAGAGTTTACTANGGATCTGTT
  TGACATTACAGAAGCTTCTTTTCATACACCCTAAAACCTCCTATTCCACATTGTTAGGAC
  AAACCACAGATTTGGGGGGAAAAAACCTCCACCATCTGTGGAAAAACTGTTTGTCCATAG
  TTCAAAAAGACCTTATCCGGAAAAATGATAGCCCCCCACAGGAAAAAAAAACCTAATGGG
  GCTCTGGCCCCCTTATAAATAACCATCGCTGGCCAAAAACCCTTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000395
• Insert Size: 5000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000395.1, NP_000386.1
• RefSeq Size: 2996 bp
• RefSeq ORF: 2694 bp
• Locus ID: 1439
• UniProt ID: P32927
• Cytogenetics: 22q12.3
• Domains: FN3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]