Adenosine A1 Receptor (ADORA1) (NM_000674) Human Untagged Clone

CAT#: SC119756

ADORA1 (untagged)-Human adenosine A1 receptor (ADORA1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Adenosine A1 Receptor
• Synonyms: RDC7
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119756 sequence for NM_000674 edited (data generated by NextGen Sequencing)
  ATGCCGCCCTCCATCTCAGCTTTCCAGGCCGCCTACATCGGCATCGAGGTGCTCATCGCC
  CTGGTCTCTGTGCCCGGGAACGTGCTGGTGATCTGGGCGGTGAAGGTGAACCAGGCGCTG
  CGGGATGCCACCTTCTGCTTCATCGTGTCGCTGGCGGTGGCTGATGTGGCCGTGGGTGCC
  CTGGTCATCCCCCTCGCCATCCTCATCAACATTGGGCCACAGACCTACTTCCACACCTGC
  CTCATGGTTGCCTGTCCGGTCCTCATCCTCACCCAGAGCTCCATCCTGGCCCTGCTGGCA
  ATTGCTGTGGACCGCTACCTCCGGGTCAAGATCCCTCTCCGGTACAAGATGGTGGTGACC
  CCCCGGAGGGCGGCGGTGGCCATAGCCGGCTGCTGGATCCTCTCCTTCGTGGTGGGACTG
  ACCCCTATGTTTGGCTGGAACAATCTGAGTGCGGTGGAGCGGGCCTGGGCAGCCAACGGC
  AGCATGGGGGAGCCCGTGATCAAGTGCGAGTTCGAGAAGGTCATCAGCATGGAGTACATG
  GTCTACTTCAACTTCTTTGTGTGGGTGCTGCCCCCGCTTCTCCTCATGGTCCTCATCTAC
  CTGGAGGTCTTCTACCTAATCCGCAAGCAGCTCAACAAGAAGGTGTCGGCCTCCTCCGGC
  GACCCGCAGAAGTACTATGGGAAGGAGCTGAAGATCGCCAAGTCGCTGGCCCTCATCCTC
  TTCCTCTTTGCCCTCAGCTGGCTGCCTTTGCACATCCTCAACTGCATCACCCTCTTCTGC
  CCGTCCTGCCACAAGCCCAGCATCCTTACCTACATTGCCATCTTCCTCACGCACGGCAAC
  TCGGCCATGAACCCCATTGTCTATGCCTTCCGCATCCAGAAGTTCCGCGTCACCTTCCTT
  AAGATTTGGAATGACCATTTCCGCTGCCAGCCTGCACCTCCCATTGACGAGGATCTCCCA
  GAAGAGAGGCCTGATGACTAG
  
  Clone variation with respect to NM_000674.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000674 unedited
  GGGGTGGGGGGGNNNGNTATTNNNNNNNNGGCGTTCAGAATTGTATACGACTCATATAGG
  CGGCCGCGAAATTCGCACGAGGCCCTACCGCGCGCGGNCCCGGACTCTGTTCCCTGGAAC
  TTTGGGCACTGCCTCTGGGACCCCTGCCGGCCAGCAGGCAGGATGGTGCTTGCCTCGTGC
  CCCTTGGTGCCCGTCTGCTGATGTGCCCAGCCTGTGCCCGCCATGCCGCCCTCCATCTCA
  GCTTTCCAGGCCGCCTACATCGGCATCGAGGTGCTCATCGCCCTGGTCTCTGTGCCCGGG
  AACGTGCTGGTGATCTGGGCGGTGAAGGTGAACCAGGCGCTGCGGGATGCCACCTTCTGC
  TTCATCGTGTCGCTGGCGGTGGCTGATGTGGCCGTGGGTGCCCTGGTCATCCCCCTCGCC
  ATCCTCATCAACATTGGGCCACAGACCTACTTCCACACCTGCCTCATGGTTGCCTGTCCG
  GTCCTCATCCTCACCCAGAGCTCCATCCTGGCCCTGCTGGCAATTGCTGTGGACCGCTAC
  CTCCGGGTCAAGATCCCTCTCCGGTACAAGATGGTGGTGACCCCCCGGAGGGCGGCGGTG
  GCCATAGCCGGCTGCTGGATCCTCTCCTTCGTGGTGGGACTGACCCCTATGTTTGGCTGG
  AACAATCTGAGTGCGGTGGAGCGGGCCTGGGCAGCCAACGGCAGCATGGGGGAGCCCGTG
  ATCAAGTGCGAGTTCGAGAAGGTCATCAGCATGGAGTACATGGTCTACTTCAACTTCTTT
  GTGTGGGTGCTGCCCCCGCTTCTCCTCATGGTCCTCATCTACCTGGNAGTCTTCTACCTA
  ATCCGCAAGCAGCTCAACAGAAAGTGTNCGNCTNCTNCGGCGACCCGCAGAAGTACTATG
  GGAAGGAGNNCTGAGATCGCAGTCGCTGGCCCTCATNCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000674 unedited
  GGTGGGGGTGTAAGTAAATTAAAAAAGCGTGGGCGNTAAACCTATTTCTGGGCCTCCTTG
  GGCACCAGGCACCCCATTTCCAACATAGGAAGGGCTTGGAAGCAAGTCCTGGAGTTGACA
  CTCATGTTCAGAAGGTCAACTCGACGGCCACCTCCCCTCCCTCGCCCCCCGCACAGGGGC
  TCCAGGATCCCCCGCCTCGCCCTCCCACACAGGGGCTCCAGGCTCCCCCGCCTCGCCCTC
  CCACACAGGGGCTCCAGGCTCCCCCACCTTGCCCCCCAACACAGGGGCTCCAGGCTTGGC
  AGGGCATGGGTTGGTCCTTCCCCAGATCCCTAAAGTCCTAGACCCCCGGACACCTGCAAC
  AGAGCTTCCAAAGCCCCTGAAAACCCAGCCAGATACTAGGGGTATTGAGGGATTCACATG
  ACAGCAAGGCCTTCCCCCACATGCTCTCAGGGGGGTACTCTCCTCTGCCTGCTGCAGCCT
  GCTAAACCCACCCCAGGGGCGCCTACAGTCAACACTGAGTCCTTACAGACACTCCCTCGT
  CCACCCCGTTCCCAGGCAGGCAGAATGCTCCCGAGTTGGCATGTCTAGTGTTCTCCTCTC
  CATCAGGCCCAGAAGCAGCAGAGATGGGGTCACCTAGGACAGTCCAGGCCCGGCAACGGG
  CAGGCCAGTGGAGCTGGTGGCCCAGATGACAGGTAATTACACTCCAGGCTCCTCCCCGGA
  AAGCTCAGGGCAAGAAGGAGGGCTCAGAGCTACCACCTCGTGTCTGGTTGAGGCCAGCAC
  CTACCGCACCAAGCTCACTTCCCAGGGCGTGGAGCCAGCCCTTCAGCAAATTTCGAAATG
  ATTACTGAACCTACCCTTTCTGGCTTTCCACGTACATTCCTGGCTGGCCCAGGGCAAGAG
  AGCAGGCACCCTACACCTGGTATGGCCTGGG
  
• Restriction Sites: Please inquire
• ACCN: NM_000674
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000674.1, NP_000665.1
• RefSeq Size: 2900 bp
• RefSeq ORF: 981 bp
• Locus ID: 134
• UniProt ID: P30542
• Cytogenetics: 1q32.1
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.