Neuropeptide Y (NPY) (NM_000905) Human Untagged Clone

CAT#: SC119601

NPY (untagged)-Human neuropeptide Y (NPY)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Neuropeptide Y
• Synonyms: PYY4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000905 edited
  ATGCTAGGTAACAAGCGACTGGGGCTGTCCGGACTGACCCTCGCCCTGTCCCTGCTCGTG
  TGCCTGGGTGCGCTGGCCGAGGCGTACCCCTCCAAGCCGGACAACCCGGGCGAGGACGCA
  CCAGCGGAGGACATGGCCAGATACTACTCGGCGCTGCGACACTACATCAACCTCATCACC
  AGGCAGAGATATGGAAAACGATCCAGCCCAGAGACACTGATTTCAGACCTCTTGATGAGA
  GAAAGCACAGAAAATGTTCCCAGAACTCGGCTTGAAGACCCTGCAATGTGGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000905 unedited
  GCACGAGGCTGGCTCTCACCCCTCGGAGACGCTCGCCCGACAGCATAGTACTTGCCGCCC
  AGCCACGCCCGCGCGCCAGCCACCATGCTAGGTAACAAGCGACTGGGGCTGTCCGGACTG
  ACCCTCGCCCTGTCCCTGCTCGTGTGCCTGGGTGCGCTGGCCGAGGCGTACCCCTCCAAG
  CCGGACAACCCGGGCGAGGACGCACCAGCGGAGGACATGGCCAGATACTACTCGGCGCTG
  CGACACTACATCAACCTCATCACCAGGCAGAGATATGGAAAACGATCCAGCCCAGAGACA
  CTGATTTCAGACCTCTTGATGAGAGAAAGCACAGAAAATGTTCCCAGAACTCGGCTTGAA
  GACCCTGCAATGTGGTGATGGGAAATGAGACTTGCTCTCTGGCCTTTTCCTATTTTCAGC
  CCATATTTCATCGTGTAAAACGAGAATCCACCCATCCTACCAATGCATGCAGCCACTGTG
  CTGAATTCTGCAATGTTTTCCTTTGTCATCATTGTATATNATGTGTGTTTAAATAAAGTA
  TCATGCATTCNAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGC
  GGCCGCGGTCATAGCTGTTTCCTGAACGATCCCCGGGTGGCATCCCTGTGACCCCTCCCC
  A
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000905 unedited
  NNTTAGCTTGNNACCGCGGCCGCAATTCTAGATCGAGTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTGAATGCATGATACTTTATTTAAACACACATATATACAATGATGACAAAG
  GAAAACATTGCAGAATTCAGCACAGTGGCTGCATGCATTGGTAGGATGGGTGGATTCTCG
  TTTTACACGATGAAATATGGGCTGAAAATAGGAAAAGGCCAGAGAGCAAGTCTCATTTCC
  CATCACCACATTGCAGGGTCTTCAAGCCGAGTTCTGGGAACATTTTCTGTGCTTTCTCTC
  ATCAAGAGGTCTGAAATCAGTGTCTCTGGGCTGGATCGTTTTCCATATCTCTGCCTGGTG
  ATGAGGTTGATGTAGTGTCCCAGCGCCGAGTAGTATCTGGCCATGTCCTCCGCTGGTGCG
  TCCTCGCCCGGGTTGTCCGGCTTGGAGGGGTACGCCTCGGCCAGCGCACCCAGGCACACG
  AGCAGGGACAGGGCGAGGGTCAATCCGGACAGCCCCAGTCGCTTGTTACCTAACATGGTG
  GCTGGCGCGCGGGCGTGGCTGGGCGGCAAGTACTATGCTGTCGGGCGAGCGTCTCCGAGG
  GGTGAGAGCCAGCCTCGTGCCGAATTCGCGGCCGCCCTATAGTGAGTCGTATTACAAAAT
  TCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCTCCCACCGTACACGCCTACCGC
  CCATTTGCGTCAACGGGGCGGGGTTATTACGACATTTTGGGAAGTCCCGTTGATTTTGGT
  GCCAAAACAACTCCCATTGACGTCAATGGGGTGGAGACTTGGAAATCCCCGTGAGTCAAC
  CGCTACCACGCCCATTGGTTACTGCCAAACCGCTCACCATGGTATAGCGAGACTAATCCT
  ANATGTCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000905
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: A TrueClone.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000905.2, NP_000896.1
• RefSeq Size: 551 bp
• RefSeq ORF: 294 bp
• Locus ID: 4852
• UniProt ID: P01303
• Cytogenetics: 7p15.3
• Domains: hormone3
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway
• Gene Summary: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]