Neurokinin 1 Receptor (TACR1) (NM_001058) Human Untagged Clone

CAT#: SC119455

TACR1 (untagged)-Human tachykinin receptor 1 (TACR1), transcript variant long

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Neurokinin 1 Receptor
• Synonyms: NK1R; NKIR; SPR; TAC1R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001058 edited
  ATGGATAACGTCCTCCCGGTGGACTCAGACCTCTCCCCAAACATCTCCACTAACACCTCG
  GAACCCAATCAGTTCGTGCAACCAGCCTGGCAAATTGTCCTTTGGGCAGCTGCCTACACG
  GTCATTGTGGTGACCTCTGTGGTGGGCAACGTGGTAGTGATGTGGATCATCTTAGCCCAC
  AAAAGAATGAGGACAGTGACGAACTATTTTCTGGTGAACCTGGCCTTCGCGGAGGCCTCC
  ATGGCTGCATTCAATACAGTGGTGAACTTCACCTATGCTGTCCACAACGAATGGTACTAC
  GGCCTGTTCTACTGCAAGTTCCACAACTTCTTTCCCATCGCCGCTGTCTTCGCCAGTATC
  TACTCCATGACGGCTGTGGCCTTTGATAGGTACATGGCCATCATACATCCCCTCCAGCCC
  CGGCTGTCAGCCACAGCCACCAAAGTGGTCATCTGTGTCATCTGGGTCCTGGCTCTCCTG
  CTGGCCTTCCCCCAGGGCTACTACTCAACCACAGAGACCATGCCCAGCAGAGTCGTGTGC
  ATGATCGAATGGCCAGAGCATCCGAACAAGATTTATGAGAAAGTGTACCACATCTGTGTG
  ACTGTGCTGATCTACTTCCTCCCCCTGCTGGTGATTGGCTATGCATACACCGTAGTGGGA
  ATCACACTATGGGCCAGTGAGATCCCCGGGGACTCCTCTGACCGCTACCACGAGCAAGTC
  TCTGCCAAGCGCAAGGTGGTCAAAATGATGATTGTCGTGGTGTGCACCTTCGCCATCTGC
  TGGCTGCCCTTCCACATCTTCTTCCTCCTGCCCTACATCAACCCAGATCTCTACCTGAAG
  AAGTTTATCCAGCAGGTCTACCTGGCCATCATGTGGCTGGCCATGAGCTCCACCATGTAC
  AACCCCATCATCTACTGCTGCCTCAATGACAGGTTCCGTCTGGGCTTCAAGCATGCCTTC
  CGGTGCTGCCCCTTCATCAGCGCCGGCGACTATGAGGGGCTGGAAATGAAATCCACCCGG
  TATCTCCAGACCCAGGGCAGTGTGTACAAAGTCAGCCGCCTGGAGACCACCATCTCCACA
  GTGGTGGGGGCCCACGAGGAGGAGCCAGAGGACGGCCCCAAGGCCACACCCTCGTCCCTG
  GACCTGACCTCCAACTGCTCTTCACGAAGTGACTCCAAGACCATGACAGAGAGCTTCAGC
  TTCTCCTCCAATGTGCTCTCCTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001058 unedited
  NNTTTTCTCGGAACGCCAGTTCANCTTTNCAAAAANAAAATGCTGCCCAGNAAAAAGCCT
  TCCACCCTCCTGTCTGGCTTTAGAAGGACCCTGAGCCCCAGGCGCCAGCCACAGGACTCT
  GCTGCAGAGGGGGGTTGTGTACAGATAGTAGGGCTTTACCGCCTAGCTTCGAAATGGATA
  ACGTCCTCCCGGTGGACTCAGACCTCTCCCCAAACATCTCCACTAACACCTCGGAACCCA
  ATCAGTTCGTGCAACCAGCCTGGCAAATTGTCCTTTGGGCAGCTGCCTACACGGTCATTG
  TGGTGACCTCTGTGGTGGGCAACGTGGTAGTGATGTGGATCATCTTAGCCCACAAAAGAA
  TGAGGACAGTGACGAACTATTTTCTGGTGAACCTGGCCTTCGCGGAGGCCTCCATGGCTG
  CATTCAATACAGTGGTGAACTTCACCTATGCTGTCCACAACGAATGGTACTACGGCCTGT
  TCTACTGCAAGTTCCACAACTTCTTTCCCATCGCCGCTGTCTTCGCCAGTATCTACTCCA
  TGACGGCTGTGGCCTTTGATAGGTACATGGCCATCATACATCCNCTCCAGCCCCGGCTGT
  CAGCCACAGCCACCAAAGTGGTCATCTGTGTCATCTGGGTCCTGGCTCTCCTGCTGGCCT
  TNCCCCAGGGCTACTACTCAACCACAGAGACCATGCCCAGCAGAGTCGTGTGCATGATCG
  AATGGCCAGAGCATCCGAACCAGATTTATGAGGAAGTGTACCACATCTGTGTGACTGTGC
  TGATCTACTTNCTCCCCCTGCTGGTGATTGGCTATGCATACCCGGTANTGGGAATCACAC
  TATGGGCCAGTGAGATCCCGGGGGACTCCTCTGACCCCTTACACGAGCAATCTTTGGCCA
  GCGCAAGGTGGTCAAAATGATGAATGCCTGC
  
  3' Read Nucleotide Sequence

  >Forward primer walk for NM_001058 unedited
  NGGCAATGTCGCCACTGCTGGCTGCCCTTCCCATCTTCTTCCTCCTGCCCTACATCAACC
  CAAATCTCTACCTGAAGAATTTATCCAGCAGGTCTACCTGGCCATCATGTGGCTGGCCAT
  GAGCTCCACCATGTACAACCCCATCATCTACTGCTGCCTCAATGACAGGTTCCGTCTGGG
  CTTCAAGCATGCCTTCCGGTGCTGCCCCTTCATCAGCGCCGGCGACTATGAGGGGCTGGA
  AATGAAATCCACCCGGTATCTCCAGACCCAGGGCAGTGTGTACAAAGTCAGCCGCCTGGA
  GACCACCATCTCCACAGTGGTGGGGGCCCACGAGGAGGAGCCAGAGGACGGCCCCAAGGC
  CACACCCTCGTCCCTGGACCTGACCTCCAACTGCTCTTCACGAAGTGACTCCAAGACCAT
  GACAGAGAGCTTCAGCTTCTCCTCCAATGTGCTCTCCTAGGCCACAGGGCCTTTGGCAGG
  TGCAGCCCCCACTGCCTTTGACCTGCCTCCCTTCATGCATGGAAATTCCCTTCATCTGGA
  ACCATCAGAAACACCCTCACACTGNGACTTGCAAAAAGGGTCAGTATGGGTTAGGGAAAA
  CATTCCATCCTTGAGTCAAAAAATCTCAATTCTTCCCTATCTTTGCCACCCTCATGCTGT
  GTGACTCANACCAAATCACTGAACTTTGCTGAGCCTGTAAAATANAAAGGTCGACCAGCT
  TTTCCCAAAAGCCCATCATTCCATTCTGGAAGTGACTTTGGCTGCATGCGAGTGCTCATT
  TCAGGATGAATTCTGCAGCACAGCTGCGGACCCGGAAGACTCATTTTTCTGGAGCCCCGT
  GTACTCCAATAAATTATCTCAAATAGACCTCTGCAGCTGGAGGCTCCATTACCCCAGCTA
  CGCTGAAAGGNTGC
  
• Restriction Sites: Please inquire
• ACCN: NM_001058
• Insert Size: 4900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001058.2, NP_001049.1
• RefSeq Size: 1766 bp
• RefSeq ORF: 1224 bp
• Locus ID: 6869
• UniProt ID: P25103
• Cytogenetics: 2p12
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]
  Transcript Variant: This variant (long) represents the longer and predominant transcript and it encodes the longer protein (isoform long). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.