CSNK2A2 (NM_001896) Human Untagged Clone

CAT#: SC118969

CSNK2A2 (untagged)-Human casein kinase 2, alpha prime polypeptide (CSNK2A2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CSNK2A2
• Synonyms: CK2A2; CK2alpha'; CSNK2A1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001896 edited
  ATGCCCGGCCCGGCCGCGGGCAGCAGGGCCCGGGTCTACGCCGAGGTGAACAGTCTGAGG
  AGCCGCGAGTACTGGGACTACGAGGCTCACGTCCCGAGCTGGGGTAATCAAGATGATTAC
  CAACTGGTTCGAAAACTTGGTCGGGGAAAATATAGTGAAGTATTTGAGGCCATTAATATC
  ACCAACAATGAGAGAGTGGTTGTAAAAATCCTGAAGCCAGTGAAGAAAAAGAAGATAAAA
  CGAGAGGTTAAGATTCTGGAGAACCTTCGTGGTGGAACAAATATCATTAAGCTGATTGAC
  ACTGTAAAGGACCCCGTGTCAAAGACACCAGCTTTGGTATTTGAATATATCAATAATACA
  GATTTTAAGCAACTCTACCAGATCCTGACAGACTTTGATATCCGGTTTTATATGTATGAA
  CTACTTAAAGCTCTGGATTACTGCCACAGCAAGGGAATCATGCACAGGGATGTGAAACCT
  CACAATGTCATGATAGATCACCAACAGAAAAAGCTGCGACTGATAGATTGGGGTCTGGCA
  GAATTCTATCATCCTGCTCAGGAGTACAATGTTCGTGTAGCCTCAAGGTACTTCAAGGGA
  CCAGAGCTCCTCGTGGACTATCAGATGTATGATTATAGCTTGGACATGTGGAGTTTGGGC
  TGTATGTTAGCAAGCATGATCTTTCGAAGGGAACCATTCTTCCATGGACAGGACAACTAT
  GACCAGCTTGTTCGCATTGCCAAGGTTCTGGGTACAGAAGAACTGTATGGGTATCTGAAG
  AAGTATCACATAGACCTAGATCCACACTTCAACGATATCCTGGGACAACATTCACGGAAA
  CGCTGGGAAAACTTTATCCATAGTGAGAACAGACACCTTGTCAGCCCTGAGGCCCTAGAT
  CTTCTGGACAAACTTCTGCGATACGACCATCAACAGAGACTGACTGCCAAAGAGGCCATG
  GAGCACCCATACTTCTACCCTGTGGTGAAGGAGCAGTCCCAGCCTTGTGCAGACAATGCT
  GTGCTTTCCAGTGGTCTCACGGCAGCACGATGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001896 unedited
  GGGGGGGCAACTTTTCTTCCTCCCCCNGGGTCAGAATTGTAAACGACTCACTATAGGCGG
  CCGCGAATCGGCACCAGCCCGCGCCCCCAGCCCGCCCGCCCCCGCGGGCCCGGCCTGGCG
  CGGCCGCCCGCCGCCGCGCTCCTCCTCCTCCTCCTCCAGCGCCCGGCGGCCCGCTGCCTC
  CTCCGCCCGACGCCCCGCGTCCCCCGCCGCGCCGCCGCCGCCACCCTCTGCGCCCCGCGC
  CGCCCCCCGGTCCCGCCCGCCATGCCCGGCCCGGCCGCGGGCAGCAGGGCCCGGGTCTAC
  GCCGAGGTGAACAGTCTGAGGAGCCGCGAGTACTGGGACTACGAGGCTCACGTCCCGAGC
  TGGGGTAATCAAGATGATTACCAACTGGTTCGAAAACTTGGTCGGGGAAAATATAGTGAA
  GTATTTGAGGCCATTAATATCACCAACAATGAGAGAGTGGTTGTAAAAATCCTGAAGCCA
  GTGAAGAAAAAGAAGATAAAACGAGAGGTTAAGATTCTGGAGAACCTTCGTGGTGGAACA
  AATATCATTAAGCTGATTGACACTGTAAAGGACCCCGTGTCAAAGACACCAGCTNTGGTA
  TTTGAATATATCAATAATACAGATTNTAAGCAACTCTACCAGATCCTGACAGACTNTGAT
  ATCCGGNTNTATATGTATGAACTACTTAAAGCTCTGGATTACTGCCACAGCCAGGGAATC
  ATGCACAGGGATGTGAAACCTCANCATGTCATGATAGATCACAACAGAAAAGCTGCGACT
  GAAGATTGGGGTCTGGCAGAAATCTATCATCCTGCTCCAGAGTACAATGTTCGTGTAGCC
  CTCAGGTACCTCAGGGGACAGNAGCTCCTCGTGACTATCAGAAGNATGAATATAGCCTGA
  ACTGTGGGAGTTTGGGCTGTATGTTACCAAGCATGATCTTTCGAGGGACCATTNCTNCTG
  GCCAGNACACTATGACAGCTGTTCCATTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001896 unedited
  NCCGTCTTACATNACCGCGCCGCAATCTANGATCGGTTTTTTTTTTTTTTTTTTTTCTTT
  TAAAACCTTTTATTCAATAATATATACTCTTTAAAATAATAATATGTAACTGGCCGCCAT
  GCCACATACTGCGCCCGTCCCCCCACTGTGGAGTCTGTGGTCAGCTAGTTAGCGTGGTTT
  GCTGGAAAAACAGGCGGCCACGGGACGAGTTGAGGGGCTCGGGGAGCAACAGTAACCAAC
  AACATTCTGCATACCCTTCACATTCCCCATGCTTTCTGGGTCGGGAAGAAGTCAACAGGA
  AGCCAAAGGCAAGTGAGCCTTTTACATTCGGAAGTGAGGTTTGATATACGGTGGTGGGCT
  GCCCTTCGCTTGGTCTAGTTCGTGCTCGCCAAACCTGCCACCGTTTTGTGTCTGCTCACG
  GAACGTGATCTCTCTATACGCGTTAAGACGTTTGATTTGGTTCTTGTTCTGCTTATGGAA
  AAGTGGGAGAACCGCAACAGACCCGTCGCTTTCCAGTCTTCATCGTGCTGCCGTGAGACC
  ACTGGAAAGCACAGCATTGTCTGCACAAGGCTGGGACTGCTCCTTCACCACAGGGTAGAA
  GTATGGGTGCTCCATGGCCTCTTTGGCAGTCAGTCTCTGTTGATGGTCGTATCGCANAAG
  TTTGTCCACGATATCTAGGGCCTCAGGGCTGACAAAGTGTCTGTTCTCACTATGGATAAA
  AGTTTCCCAGCGTTTTCCGTGAATGTTTGTCCCAAGGATATCGTTGGAAGTGGGGGATCT
  AGGTCTATGTGGATACCTCTTCAAATACCCCTACAAGTTCTCTTGTTCCCAGAACCCTTG
  GCATTGCCAACCAAGCTGGTCATAGTTGTCCCTGTCCCTGGGAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001896
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001896.2, NP_001887.1
• RefSeq Size: 1674 bp
• RefSeq ORF: 1053 bp
• Locus ID: 1459
• UniProt ID: P19784
• Cytogenetics: 16q21
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adherens junction, Tight junction, Wnt signaling pathway
• Gene Summary: This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017]