CCDC93 (NM_019044) Human Untagged Clone

CAT#: SC113308

CCDC93 (untagged)-Human coiled-coil domain containing 93 (CCDC93)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCDC93
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_019044, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGTTGCCCAGGGGGCCGGAGGGCCAGGGTCTCCCGGAGGTGGAAACAAGAGAAGATGAAGAACAAA
  ATGTCAAGTTGACTGAAATTCTGGAGCTCTTGGTTGCAGCTGGGTATTTCAGGGCAAGAATTAAAGGCTT
  ATCACCCTTTGACAAGGTAGTAGGAGGAATGACTTGGTGTATCACCACTTGCAACTTTGATGTAGATGTT
  GATTTGCTCTTTCAAGAAAACTCTACGATAGGTCAAAAAATAGCTCTGTCAGAAAAAATTGTCTCGGTCC
  TGCCAAGGATGAAATGCCCACACCAGCTGGAGCCCCACCAGATCCAGGGGATGGATTTTATTCACATATT
  TCCTGTTGTTCAGTGGCTGGTGAAACGAGCTATAGAAACAAAAGAAGAGATGGGTGACTATATCCGCTCC
  TACTCTGTATCCCAGTTCCAGAAGACTTACAGTCTCCCTGAGGATGATGACTTCATAAAGAGAAAAGAAA
  AGGCCATCAAGACAGTTGTGGACCTCTCAGAAGTGTACAAGCCCCGTCGGAAATACAAACGCCACCAGGG
  AGCAGAGGAGCTACTTGATGAAGAATCTCGAATCCATGCTACACTTTTGGAATATGGCAGGAGATATGGA
  TTTAGCCGCCAGAGCAAAATGGAGAAGGCTGAGGACAAGAAAACGGCACTTCCAGCAGGGCTGTCAGCTA
  CAGAAAAAGCTGATGCCCACGAGGAAGATGAGCTTCGAGCAGCTGAAGAGCAGCGTATTCAGTCGCTGAT
  GACCAAGATGACCGCTATGGCAAATGAGGAGAGCCGTCTCACCGCAAGCTCCGTGGGCCAGATTGTGGGA
  CTCTGCTCTGCTGAGATCAAGCAGATTGTGTCCGAGTATGCAGAGAAGCAGTCTGAGCTATCAGCTGAAG
  AAAGTCCAGAAAAATTAGGAACCTCCCAGCTACATCGCCGGAAAGTCATTTCCTTGAACAAACAGATTGC
  GCAAAAGACCAAACATCTTGAAGAGCTGCGAGCAAGTCACACCAGCCTACAAGCCAGATATAATGAAGCC
  AAGAAAACGCTGACAGAGCTGAAGACTTACAGTGAGAAACTGGACAAAGAGCAAGCAGCCCTCGAGAAGA
  TAGAATCCAAAGCTGATCCAAGTATCCTACAGAACCTGAGAGCACTTGTAGCCATGAATGAAAATCTGAA
  AAGTCAAGAACAGGAATTTAAAGCACATTGTCGAGAGGAGATGACACGACTACAGCAAGAAATTGAAAAC
  CTGAAAGCTGAGAGAGCACCACGTGGAGATGAAAAGACCCTCTCCAGTGGAGAGCCGCCTGGTACCTTGA
  CCTCTGCAATGACTCATGACGAAGACCTAGACAGACGGTATAATATGGAGAAAGAGAAACTTTACAAGAT
  ACGTTTACTACAGGCTCGAAGAAATCGAGAAATAGCAATTTTGCACCGCAAGATTGATGAAGTCCCTAGC
  CGTGCCGAGCTAATACAGTATCAGAAGAGATTTATTGAACTCTACCGCCAGATTTCAGCAGTGCACAAAG
  AAACCAAGCAGTTCTTCACTTTATATAATACCCTGGATGATAAAAAGGTTTATTTGGAAAAAGAGATTAG
  TCTGCTGAACTCAATTCATGAGAACTTCTCACAGGCCATGGCCTCCCCTGCTGCCCGGGACCAGTTTTTA
  CGTCAGATGGAACAGATTGTGGAAGGAATTAAGCAAAGTAGAATGAAGATGGAAAAGAAAAAGCAAGAGA
  ACAAAATGAGAAGAGACCAGTTGAACGACCAGTACTTGGAGCTGTTAGAAAAGCAGAGGCTATACTTTAA
  GACTGTGAAAGAGTTCAAGGAGGAGGGCCGCAAGAACGAGATGCTGCTGTCCAAGGTGAAAGCGAAGGCC
  TCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_019044 unedited
  ATAGGCGGGCCGCGAATTCGCACGAGGCCGGAAAGTCATTTCCTTGAACAAACAGATTGC
  GCAAAAGACCAAACATCTTGAAGAGCTGCGAGCAAGTCACACCAGCCTACAAGCCAGATA
  TAATGAAGCCAAGAAAACGCTGACAGAGCTGAAGACTTACAGTGAGAAACTGGACAAAGA
  GCAAGCAGCCCTCGAGAAGATAGAATCCAAAGCTGATCCAAGTATCCTACAGAACCTGAG
  AGCACTTGTAGCCATGAATGAAAATCTGAAAAGTCAAGAACAGGAATTTAAAGCACTGTC
  GAGAGGAGATGACACGACTACAGCAAGAAATTGAAAACCTGAAAGCTGAGAGAGCACCAC
  GTGGAGATGAAAAGACCCTCTCCAGTGGAGAGCCGCCTGGTACCTTGACCTCTGCAATGA
  CTCATGACGAAGACCTAGACAGACGGTATAATATGGAGAAAGAGAAACTTTACAAGATAC
  GTTTACTACAGGCTCGAAGAAATCGAGAAATAGCAATTTTGCACCGCAAGATTGATGAAG
  TCCCTAGCCGTGCCGAGCTAATACAGTATCAGAAGAGATTTATTGAACTCTACCGCCAGA
  TTTCAGCAGTGCACANAGAAACCAAGCAGTTCTTCACTTTATATAATACCCCTGGATGAT
  AAAAAGGTTTATTTGGAAAAAGAGATTAGTCTGCTGAAACTCATTATGAGAACTTCTACA
  GTNAGTACTGTCAAGTCTTCTTTCCACTATACCCTGCCGGNCTGCGCTTTGATTCAGCCC
  ACTCACATGCTATANTGTGCTTTGACAAGTACATGCAGACTTACACTGGGTATGNGATTC
  TACTCTTTAGCCTTCTGCTAGATCTTGTTAACCTCTCTTGGGTCTGCAACTTTAGGTTNN
  AAGTGAAGGAAACTGCCAAAAGTTACTTCAAACTTTGCGGGCCCACTCTAAATTTTGGTG
  TTATAATAAATTGGTATGAACAAAGAGCTTAATTACTAGGATTTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_019044
• Insert Size: 4840 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_019044.2, NP_061917.2
• RefSeq Size: 6946 bp
• RefSeq ORF: 1728 bp
• Locus ID: 54520
• UniProt ID: Q567U6
• Cytogenetics: 2q14.1
• Gene Summary: Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (PubMed:28892079, PubMed:25355947). Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947).[UniProtKB/Swiss-Prot Function]