FKBP14 (NM_017946) Human Untagged Clone

CAT#: SC108712

FKBP14 (untagged)-Human FK506 binding protein 14, 22 kDa (FKBP14)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FKBP14
• Synonyms: EDSKMH; EDSKSCL2; FKBP22; IPBP12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108712 sequence for NM_017946 edited (data generated by NextGen Sequencing)
  ATGAGGCTTTTCTTGTGGAACGCGGTCTTGACTCTGTTCGTCACTTCTTTGATTGGGGCT
  TTGATCCCTGAACCAGAAGTGAAAATTGAAGTTCTCCAGAAGCCATTCATCTGCCATCGC
  AAGACCAAAGGAGGGGATTTGATGTTGGTCCACTATGAAGGCTACTTAGAAAAGGACGGC
  TCCTTATTTCACTCCACTCACAAACATAACAATGGTCAGCCCATTTGGTTTACCCTGGGC
  ATCCTGGAGGCTCTCAAAGGTTGGGACCAGGGCTTGAAAGGAATGTGTGTAGGAGAGAAG
  AGAAAGCTCATCATTCCTCCTGCTCTGGGCTATGGAAAAGAAGGAAAAGGTAAAATTCCC
  CCAGAAAGTACACTGATATTTAATATTGATCTCCTGGAGATTCGAAATGGACCAAGATCC
  CATGAATCATTCCAAGAAATGGATCTTAATGATGACTGGAAACTCTCTAAAGATGAGGTT
  AAAGCATATTTAAAGAAGGAGTTTGAAAAACATGGTGCGGTGGTGAATGAAAGTCATCAT
  GATGCTTTGGTGGAGGATATTTTTGATAAAGAAGATGAAGACAAAGATGGGTTTATATCT
  GCCAGAGAATTTACATATAAACACGATGAGTTATAG
  
  Clone variation with respect to NM_017946.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017946 unedited
  GTCACGAACAGNAAACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGACCCTTGATA
  AAAAGTTGGTGGTAAATGTGCCACGTCTTCTAAGAAGGGGAGTCCTGAACTTGTCTGAAG
  CCCTTGTCCGTAAGCCTTGAACTACGTTCTTAAATCTATGAAGTCGAGGGACCTTTCGCT
  GCTTTTGTAGGGACTTCTTTCCTTGCTTCAGCAACATGAGGCTTTTCTTGTGGAACGCGG
  TCTTGACTCTGTTCGTCACTTCTTTGATTGGGGCTTTGATCCCTGAACCAGAAGTGAAAA
  TTGAAGTTCTCCAGAAGCCATTCATCTGCCATCGCAAGACCAAAGGAGGGGATTTGATGT
  TGGTCCACTATGAAGGCTACTTAGAAAAGGACGGCTCCTTATTTCACTCCACTCACAAAC
  ATAACAATGGTCAGCCCATTTGGTTTACCCTGGGCATCCTGGAGGCTCTCAAAGGTTGGG
  ACCAGGGCTTGAAAGGAATGTGTGTAGGAGAGAAGAGAAAGCTCATCATTCCTCCTGCTC
  TGGGCTATGGAAAAGAAGGAAAAGGTAAAATTCCCCCAGAAAGTACACTGATATTTAATA
  TTGATCTCCTGGAGATTCGAAATGGACCAAGATCCCATGAATCATTCCAAGAAATGGATC
  TTAATGATGACTGNGAACTCTCTANAGATGANGTTAAAGCATATNTAAAGAAGGAGTTTG
  AAAAACATGGTGCGGTGGTGAATGAAAGTCATCATGATGCCTTGGTGGNNAGATATTTTG
  ATAAAGAAGATGAAGACCAAGATGGGTTTATATCTGCCAGAGAATTTCATANTAACACCG
  ATGAGTATAGAGAAACATCTACCCTTTTAATATAGCACTCATCTTTCAAGAGAGGCAGTC
  ATCTTTAAAGAACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017946 unedited
  TGGCCGCGGCCGCATCTAGATCGAGTTTTTTTTTTTTTTTTTTGAGAGGAGTCTTGCTCT
  GTCACCCAGGCTGGAGTGCAGTGGCACAATCTTGGCTCACTGCAACCTCCGCCTCCCGGG
  TTCAAGCAAATCTCCTGTCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGTGCACCACCA
  CGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAAAGTTTCACCATGTTGGCCAGGCTGG
  TCTTGAACTCCTGATCTCAAGTGATCCACCCTCCTTGGCCCCCAAAGTGCTGGGATTACA
  GGCATGAGCCACCACACCCAGCTAACTTCAGTTTTTGATGAGACAGAAATGGGAAAATGT
  AGACTGGTTTACTACTTTATCTTATGATACAATGTTATTGTAGTATAATATACTATAGAC
  TACCCATTAAAGAACCAGGAAGGATATTCCGCTAGCCTTAAGAAGTAAATATTGAATATA
  AATATAACTTTCTACCTCATCTATAACATATTGATACATTCTATTACAAAGAAACTCACA
  CATAAATGATTTGTCCTATTTATCATAATAGGCCACCAATCACTAGGAGCCAAGCTTCAT
  TAGCTTAAGTCCTAGGTAGCATGTCTCAATGCATACATTATTTATATGTTATTAACCGTG
  TTTCTTTTTTTTTTTCGAACAGAGTGTCAAGCTTAAGGTGATCTCGGCTTACCGACCTCC
  GCCTTCGGTTAAGCGATCTGCCGCCCAACCTCCTGGGAGCTTGGTTACAGGCACCCTCCC
  CCCCCCGCTCTTTTGTTTTTCATAAAAAAGGTTCTCCCGGTGGTTAGCTGCTCCAACTCC
  ACCTGAGGAACCGCCCCTTTACCTCCATCGGCGGATTCAGGTCGCCCCCTTCCCCGCTTT
  ACCTGTTTTTACCCACCTCCACTCCCTTCGATAGTTCCTAAAATGGGCTAACCCTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017946
• Insert Size: 2340 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_017946.2, NP_060416.1
• RefSeq Size: 2247 bp
• RefSeq ORF: 636 bp
• Locus ID: 55033
• UniProt ID: Q9NWM8
• Cytogenetics: 7p14.3
• Domains: FKBP, EFh
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate protein folding. Defects in this gene are a cause of a type of Ehlers-Danlos syndrome (EDS). Both a protein-coding variant and noncoding variants are transcribed from this gene. [provided by RefSeq, Mar 2012]
  Transcript Variant: This variant (1) represents the protein-coding transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.