ECRG4 (NM_032411) Human Untagged Clone

CAT#: SC104814

C2orf40 (untagged)-Human chromosome 2 open reading frame 40 (C2orf40)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ECRG4
• Synonyms: C2orf40
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC104814 sequence for NM_032411 edited (data generated by NextGen Sequencing)
  ATGGCTGCCTCCCCCGCGCGGCCTGCTGTCCTGGCCCTGACCGGGCTGGCGCTGCTCCTG
  CTCCTGTGCTGGGGCCCAGGTGGCATAAGTGGAAATAAACTCAAGCTGATGCTTCAAAAA
  CGAGAAGCACCTGTTCCAACTAAGACTAAAGTGGCCGTTGATGAGAATAAAGCCAAAGAA
  TTCCTTGGCAGCCTGAAGCGCCAGAAGCGGCAGCTGTGGGACCGGACTCGGCCCGAGGTG
  CAGCAGTGGTACCAGCAGTTTCTCTACATGGGCTTTGACGAAGCGAAATTTGAAGATGAC
  ATCACCTATTGGCTTAACAGAGATCGAAATGGACATGAATACTATGGCGATTACTACCAA
  CGTCACTATGATGAAGACTCTGCAATTGGTCCCCGGAGCCCCTACGGCTTTAGGCATGGA
  GCCAGCGTCAACTACGATGACTACTAA
  
  Clone variation with respect to NM_032411.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032411 unedited
  GCGGATTCGGCACCAGCCGGTTCTCCCTCGCAGCACCTCGAAGTGCGCCCCTCGCCCTCC
  TGCTCGCGCCCCGCCGCCATGGCTGCCTCCCCCGCGCGGCCTGCTGTCCTGGCCCTGACC
  GGGCTGGCGCTGCTCCTGCTCCTGTGCTGGGGCCCAGGTGGCATAAGTGGAAATAAACTC
  AAGCTGATGCTTCAAAAACGAGAAGCACCTGTTCCAACTAAGACTAAAGTGGCCGTTGAT
  GAGAATAAAGCCAAAGAATTCCTTGGCAGCCTGAAGCGCCAGAAGCGGCAGCTGTGGGAC
  CGGACTCGGCCCGAGGTGCAGCAGTGGTACCAGCAGTTTCTCTACATGGGCTTTGACGAA
  GCGAAATTTGAAGATGACATCACCTATTGGCTTAACAGAGATCGAAATGGACATGAATAC
  TATGGCGATTACTACCAACGTCACTATGATGAAGACTCTGCAATTGGTCCCCGGAGCCCC
  TACGGCTTTAAGCATGGAACCCAGCGTAACTACGATGACTACTAACCATGACTTGCCACA
  GGCTGGACCAAAAACAAATACCGATTTTCTTTATGGGTCCCCAAATGGCCTACACTTCTT
  GGGTTTCTGATCCGCCCCACCCTCACAAATCTTTTGCCCCACCCTGTGGGAACAACAACC
  ACCCGTCCCCCCCCCTCACTGCAATGGCCCCCCATCGTTCTCAGGTACAGACTTTATTTA
  ACAACACAACAATACCATCCCTCCAAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_032411 unedited
  CTCTGAACCGCGCCGCATTCTATGATCGGTTTTTTTTTTTTTTTTTTTAACAAAATGCTT
  TATTTCTATTTTTAAATGAGAGGCATTCCCATGAAATATCAAAAGGCATTTACATGTGTT
  GTTTTAACTCTTCTTTTTTGATCACACAAAGTAGGTAGAAAAGATCTGCTGAAATAGAGC
  AAATCAGAAACCAAGTAGTGTAAGGCATTAGGAGATACATGAAGAGAATCGCTATTTGCT
  TCTTGTACAGCGTGTGGCAAGTCATGGTTAGTAGTCATCGTAGTTGACGCTGGCTCCATG
  CCTAAAGCCGTAGGGGCTCCGGGGACCAATTGCAGAGTGTTGATGATAGTGACGTCGGAG
  CAGGCGCGCGCCAGTATGGGTCGCGGTGCCCGACGCTCCCGATCGCTCGTCTGTCCCTGC
  TGCTTATCGCCCGGTCCACCCCCTTTGCGCTGCCACCCACCCCCCGCGCCTCCCCCCGCC
  CGCATGCCCGGACTCCTTCGTTCCCTTCTCCCCCCCCCCCCTCATCCCTGCTTCCACTCA
  TATTTCGTCCCCTCCCCTCCTCCCCACCTTCTTCTTCACCCCTTGGTTAGTTGCCAGTCA
  CCCCCTGGCCGATCCTCTGCACTTTCGCGTACCTTTTTGGTCCTCACACCCCCCCTTCTT
  AATCTCCTGCCCTGTTTACATGACCTCCTCATGTGCAATACTCTCTCACTGCCTTCTCTC
  CGCAAACTATGCCATCCCTATACTATCTCCCCCCCCCCCTTCCCCACTACAGCTGCTTCT
  CTTCCCATCCTATTCACGACCCACCTCCCCTTACTACCTTCCCTCCTCTTGTATGTATTT
  GTAGCCGCTTTTTCCCCCACCCCCACCCCCTCCGCTCTTCCCACTATCACACCTTTTCCT
  AGTCCCCGCTCATACTACACTTACCCTCACCGCTCCTACACCCCACCATCGCCGTGNCCA
  TACAATTATTTTTCCTTCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_032411
• Insert Size: 780 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_032411.1, NP_115787.1
• RefSeq Size: 772 bp
• RefSeq ORF: 447 bp
• Locus ID: 84417
• UniProt ID: Q9H1Z8
• Cytogenetics: 2q12.2
• Protein Families: Secreted Protein, Transmembrane
• Gene Summary: Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function]