UNC5B (AK094595) Human Untagged Clone

CAT#: SC104278

(untagged)-Human cDNA FLJ37276 fis, clone BRAMY2012426, highly similar to Rattus norvegicus transmembrane receptor Unc5H2 mRNA

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UNC5B
• Synonyms: p53RDL1; UNC5H2
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for AK094595 edited
  GAATTCGGCACGAGGCCACCATCTGCCCAGTCGATGGGGCGTGGACGGAGTGGAGCAAGT
  GGTCAGCCTGCAGCACTGAGTGTGCCCACTGGCGTAGCCGCGAGTGCATGGCGCCCCCAC
  CCCAGAACGGAGGCCGTGACTGCAGCGGGACGCTGCTCGACTCTAAGAACTGCACAGATG
  GGCTGTGCATGCAAAATAAGAAAACTCTAAGCGACCCCAACAGCCACCTGCTGGAGGCCT
  CAGGGGATGCGGCGCTGTATGCGGGGCTCGTGGTGGCCATCTTCGTGGTCGTGGCAATCC
  TCATGGCGGTGGGGGTGGTGGTGTACCGCCGCAACTGCCGTGACTTCGACACAGACATCA
  CTGACTCATCTGCTGCCCTGACTGGTGGTTTCCACCCCGTCAACTTTAAGACGGCAAGGC
  CCAGCAACCCGCAGCTCCTACACCCCTCTGTGCCTCCTGACCTGACAGCCAGCGCCGGCA
  TCTACCGCGGACCCGTGTATGCCCTGCAGGACTCCACCGACAAAATCCCCATGACCAACT
  CTCCTCTGCTGGACCCCTTACCCAGCCTTAAGGTCAAGGTCTACAGCTCCAGCACCACGG
  GCTCTGGGCCAGGCCTGGCAGATGGGGCTGACCTGCTGGGGGTCTTGCCGCCTGGCACAT
  ACCCTAGCGATTTCGCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCTCGGTT
  CCCAGCAGCTCTTGGGCCTGCCCCGAGACCCAGGGAGCAGCGTCAGCGGCACCTTTGGCT
  GCCTGGGTGGGAGGCTCAGCATCCCCGGCACAGGGGTCAGCTTGCTGGTGCCCAATGGAG
  CCATTCCCCAGGGCAAGTTCTACGAGATGTATCTACTCATCAACAAGGCAGAAAGTACCC
  TCCCGCTTTCAGAAGGGACCCAGACAGTATTGAGCCCCTCGGTGACCTGTGGACCCACAG
  GCCTCCTGCTGTGCCGCCCCGTCATCCTCACCATGCCCCACTGTGCCGAAGTCAGTGCCC
  GTGACTGGATCTTTCAGCTCAAGACCCAGGCCCACCAGGGCCACTGGGAGGAGGTGGTGA
  CCCTGGATGAGGAGACCCTGAACACACCCTGCTACTGCCAGCTGGAGCCCAGGGCCTGTC
  ACATCCTGCTGGACCAGCTGGGCACCTACGTGTTCACGGGCGAGTCCTATTCCCGCTCAG
  CAGTCAAGCGGCTCCAGCTGGCCGTCTTCGCCCCCGCCCTCTGCACCTCCCTGGAGTACA
  GCCTCCGGGTCTACTGCCTGGAGGACACGCCTGTAGCACTGAAGGAGGTGCTGGAGCTGG
  AGCGGACTCTGGGCGGATACTTGGTGGAGGAGCCGAAACCGCTAATGTTCAAGGACAGTT
  ACCACAACCTGCGCCTCTCCCTCCATGACCTCCCCCATGCCCATTGGAGGAGCAAGCTGC
  TGGCCAAATACCAGGAGATCCCCTTCTATCACATTTGGAGTGGCAGCCAGAAGGCCCTCC
  ACTGCACTTTCACCCTGGAGAGGCACAGCTTGGCCTCCACAGAGCTCACCTGCAAGATCT
  GCGTGCGGCAAGTGGAAGGGGAGGGCCAGATATTCCAGCTGCATACCACTCTGGCAGAGA
  CACCTGCTGGCTCCCTGGACACTCTCTGCTCTGCCCCTGGCAGCACTGTCACCACCCAGC
  TGGGACCTTATGCCTTCAAGATCCCACTGTCCATCCGCCAGAAGATATGCAACAGCCTAG
  ATGCCCCCAACTCACGGGGCAATGACTGGCGGATGTTAGCACAGAAGCTCTCTATGGACC
  GGTACCTGAATTACTTTGCCACCAAAGCGAGCCCCACGGGTGTGATCCTGGACCTCTGGG
  AAGCTCTGCAGCAGGACGATGGGGACCTCAACAGCCTGGCGAGTGCCTTGGAGGAGATGG
  GCAAGAGTGAGATGCTGGTGGCTGTGGCCACCGACGGGGACTGCTGAGCCTCCTGGGACA
  GCGGGCTGGCAGGGACTGGCAGGAGGCAGGTGCAGGGAGGCCTGGGGCAGCCTCCTGATG
  GGGATGTTTGGCCTCTGCTTCCTCCCAGTTCACAGCCAGAGTTGCCTCTCCTCCTCCTCT
  TCCCCAACCCCCAGACCATGACCAGCCTTAGAAAATCCATGTACTCTGTTGTTAGAGGGC
  CCAGAGTTCCTTCTCCACCCCCGCTCTCTCTCTCTTGGCCTGAGATCTCTGTGCAGGAAC
  CAAGATGGGGCTGAAGCCTCTGGAGGCAGTTGGTTGGGGGCGGGCAGGCAGGAGGCCCTC
  CCTCCACCCCCCCACCCTCAGCCCGGCAACTTCTGGGTTCCATGGGTTTTAGTTCCGTTC
  TTCGTTTTCTTCCTCCGTTATTGATTTCTCCTTTCTCCCTAAGCCCCCTTCTGCTTCCAC
  GCCCTTTTCCTCTTTGAAGAGTCAAGTACAATTCAGACAAACTGCTTTCTCCTGTCCAAA
  AGCAAAAAGGCAAAGGAAAGAAAGAAAGCTTCAGACCGCTAGTAAGGCTCAAAGAAGAAG
  AAAAACACCAAAACCACAAGGGAAAAGAAAAACCCAGTTTCTTAGGAAACGCAAACGATT
  TATTATCCAGATTATTTGGATAAGTCCTTTTTAAGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK094595 unedited
  NCTTATTACCCCCGCCCGTTCCCGCTTTGGGCGGTAGGCGTGTACGGTGGNGAGTCTATA
  TAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGG
  CCGCGAATTCGGCACGAGGCCACCATCTGCCCAGTCGATGGGGCGTGGACGGAGTGGAGC
  AAGTGGTCAGCCTGCAGCACTGAGTGTGCCCACTGGCGTAGCCGCGAGTGCATGGCGCCC
  CCACCCCAGAACGGAGGCCGTGACTGCAGCGGGACGCTGCTCGACTCTAAGAACTGCACA
  GATGGGCTGTGCATGCAAAATAAGAAAACTCTAAGCGACCCCAACAGCCACCTGCTGGAG
  GCCTCAGGGGATGCGGCGCTGTATGCGGGGCTCGTGGTGGCCATCTTCGTGGTCGTGGCA
  ATCCTCATGGCGGTGGGGGTGGTGGTGTACCGCCGCAACTGCCGTGACTTCGACACAGAC
  ATCACTGACTCATCTGCTGCCCTGACTGGTGGTTTCCACCCCGTCAACTTTAAGACGGCA
  AGGCCCAGCAACCCGCAGCTCCTACACCCCTCTGTGCCTCCTGACCTGACAGCCAGCGCC
  GGCATCTACCGCGGACCCGTGTATGCCCTGCAGGACTCCACCGACAAAATCCCCATGACC
  AACTCTCCTCTGCTGGACCCCTTACCCAGCCTTAAGGTCAAGGTCTACAGCTCCAGCACC
  ACGGGCTCTGGGCCAGGCCTGGCAGATGGGGCTGACCTGCTGGGGGTCTTGCCGCCTGGC
  ACATACCCTAGCGATTTCGCCCGGGACACCCACTTCCTGCACCTGCGCAGCGCCAGCCCT
  CGGTTCCCAGCAGCTCCTTGGGCCTGNCCCGAGACCCAGGNAGCAGCGTCAGCGGCACCT
  TTGGCTGCCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AK094595 unedited
  TCTTGGTATACTATGNACCGCGCCGCTATCTANGATCGATTTTTTTTTTTTTTTTTTCTT
  AAAAGGACTTATCCAAATAATCTGGATAATAAATCGTTTGCGTTTCCTAAGAAACTGGGT
  TTTTCTTTTCCCTTGTGGTTTTGGTGTTTTTCTTCTTCTTTGAGCCTTACTAGCGGTCTG
  AAGCTTTCTTTCTTTCCTTAGCCTTTTTGCTTTTGGACAGGAGAAAGCAGTTTGTCTGAA
  TTGTACTTGACTCTTCAAAGAGGAAAAGGGCGTGGAAGCAGAAGGGGGCTTAGGGAGAAA
  GGAGAAATCAATAACGGAGGAAGAAAACGAAGAACGGAACTAAAACCCATGGAACCCAGA
  AGTTGCCGGGCTGAGGGTGGGGGGGTGGAGGGAGGNNCCNCCNNCCNNCCCCCCCCCCAA
  CCACACCCCCCCCAACCCACAACCCCCGCCCCCNCCCCCCCCCCACCACCAGACCTCACA
  AAAACCACACCACCCACACACCAACACACGCCACTGAGCAACAACAAACCACCCAACACA
  AACGCCCACCCCCCCCCCACACACCCAACCACCACTAACCACCAGCATTTTNNNNNNNNA
  AANANNAGGACGCGGCCACAACANCCCCAAACCAACACAACCACACCACCCCCACACCCA
  AAGACCCCCCACCCCACCCCACCCCCACCACGGGCCGGGCGGAGGGAAACCACATACCGN
  NGGNGGNNANNGANGNNACCGCAGCCCCAAGAAAAGGAACAGCGCCAAAAACAACGCACC
  GCCAAAAGCATACCCACACCCGCNTCGCCGCAGAGGGGAATAAGAAGTCTCTTACTTTTA
  TACATATCCCACTCACACCAACCAACAGAGTATGTGGGGGGGGGGGATG
  
• Restriction Sites: NotI-NotI
• ACCN: AK094595
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AK094595.1, BAC04382.1
• RefSeq Size: 2406 bp
• RefSeq ORF: 2406 bp
• Locus ID: 219699
• Cytogenetics: 10q22.1
• Domains: DEATH, ZU5
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• Gene Summary: This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]