MPP2 (NM_001278372) Human Tagged ORF Clone

CAT#: RG238957

MPP2 (tGFP-tagged) - Human membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (MPP2), transcript variant 4

Product Images

Circular map for RG238957

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: MPP2
• Synonyms: DLG2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238957 representing NM_001278372.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCCGGTTGCCGCCACCAACTCTGAAACTGCCATGCAGCAAGTCCTGGACAACTTGGGATCCCTCCCC
  AGTGCCACGGGGGCTGCAGAGCTGGACCTGATCTTCCTTCGAGGCATTATGGAAAGTCCCATAGTAAGA
  TCCCTGGCCAAGGTGATAATGGTATTGTGGTTTATGCAGCAGAATGTCTTTGTTCCTATGAAATACATG
  CTGAAATACTTTGGGGCCCATGAGAGGCTGGAGGAGACGAAGCTGGAGGCCGTGAGAGACAACAACCTG
  GAGCTGGTGCAGGAGATCCTGCGGGACCTGGCGCAGCTGGCTGAGCAGAGCAGCACAGCCGCCGAGCTG
  GCCCACATCCTCCAGGAGCCCCACTTCCAGTCCCTCCTGGAGACGCACGACTCTGTGGCCTCAAAGACC
  TATGAGACACCACCCCCCAGCCCTGGCCTGGACCCTACATTCAGCAACCAGCCTGTACCTCCCGATGCT
  GTGCGCATGGTGGGCATCCGCAAGACAGCCGGAGAACATCTGGGTGTAACGTTCCGCGTGGAGGGCGGC
  GAGCTGGTGATCGCGCGCATTCTGCATGGGGGCATGGTGGCTCAACAAGGCCTGCTGCATGTGGGTGAC
  ATCATCAAGGAGGTGAACGGGCAGCCAGTGGGCAGTGACCCCCGCGCACTGCAGGAGCTCCTGCGCAAT
  GCCAGTGGCAGTGTCATCCTCAAGATCCTGCCCAGCTACCAGGAGCCCCATCTGCCCCGCCAGGTATTT
  GTGAAATGTCACTTTGACTATGACCCGGCCCGAGACAGCCTCATCCCCTGCAAGGAAGCAGGCCTGCGC
  TTCAACGCCGGGGACTTGCTCCAGATCGTAAACCAGGATGATGCCAACTGGTGGCAGGCATGCCATGTC
  GAAGGGGGCAGTGCTGGGCTCATTCCCAGCCAGCTGCTGGAGGAGAAGCGGAAAGCATTTGTCAAGAGG
  GACCTGGAGCTGACACCAAACTCAGGGACCCTATGCGGCAGCCTTTCAGGAAAGAAAAAGAAGCGAATG
  ATGTATTTGACCACCAAGAATGCAGAGTTTGACCGTCATGAGCTGCTCATTTATGAGGAGGTGGCCCGC
  ATGCCCCCGTTCCGCCGGAAAACCCTGGTACTGATTGGGGCTCAGGGCGTGGGACGGCGCAGCCTGAAG
  AACAAGCTCATCATGTGGGATCCAGATCGCTATGGCACCACGGTGCCCTACACCTCCCGGCGGCCGAAA
  GACTCAGAGCGGGAAGGTCAGGGTTACAGCTTTGTGTCCCGTGGGGAGATGGAGGCTGACGTCCGTGCT
  GGGCGCTACCTGGAGCATGGCGAATACGAGGGCAACCTGTATGGCACACGTATTGACTCCATCCGGGGC
  GTGGTCGCTGCTGGGAAGGTGTGCGTGCTGGATGTCAACCCCCAGGCGGTGAAGGTGCTACGAACGGCC
  GAGTTTGTCCCTTACGTGGTGTTCATCGAGGCCCCAGACTTCGAGACCCTGCGGGCCATGAACAGGGCT
  GCGCTGGAGAGTGGAATATCCACCAAGCAGCTCACGGAGGCGGACCTGAGACGGACAGTGGAGGAGAGC
  AGCCGCATCCAGCGGGGCTACGGGCACTACTTTGACCTCTGCCTGGTCAATAGCAACCTGGAGAGGACC
  TTCCGCGAGCTCCAGACAGCCATGGAGAAGCTACGGACAGAGCCCCAGTGGGTGCCTGTCAGCTGGGTG
  TAC
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238957
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MPVAATNSETAMQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKVIMVLWFMQQNVFVPMKYM
  LKYFGAHERLEETKLEAVRDNNLELVQEILRDLAQLAEQSSTAAELAHILQEPHFQSLLETHDSVASKT
  YETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGD
  IIKEVNGQPVGSDPRALQELLRNASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLR
  FNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQLLEEKRKAFVKRDLELTPNSGTLCGSLSGKKKKRM
  MYLTTKNAEFDRHELLIYEEVARMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPK
  DSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTA
  EFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERT
  FRELQTAMEKLRTEPQWVPVSWVY
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001278372
• ORF Size: 1728 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).

Reference Data

• RefSeq: NM_001278372.2
• RefSeq Size: 4717 bp
• RefSeq ORF: 1731 bp
• Locus ID: 4355
• UniProt ID: Q14168
• Cytogenetics: 17q21.31
• Protein Families: Druggable Genome
• MW: 65 kDa
• Gene Summary: Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008]