ATF 4(ATF4) (NM_001675) Human Tagged ORF Clone

CAT#: RC222709L1

Lenti-ORF clone of ATF4 (Myc-DDK-tagged)-Human activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4), transcript variant 1

Change vector?

  • LentiORF®

USD 763


Availability*
In Stock

Size
    • 10 ug

Product images

Specifications

Product Data
Product Name ATF 4(ATF4) (NM_001675) Human Tagged ORF Clone
Symbol ATF4
Synonyms CREB-2; CREB2; TAXREB67; TXREB
Vector pLenti-C-Myc-DDK
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC222709).
Restriction Sites SgfI-MluI      Cloning Scheme for this gene     
Tag Myc-DDK
ACCN NM_001675
ORF Size 1053 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Reference Data
RefSeq NM_001675.2, NP_001666
RefSeq Size 2022
RefSeq ORF 1056
Locus ID 468
Cytogenetics 22q13.1
Domains BRLZ
Protein Families Transcription Factors
Protein Pathways MAPK signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, GnRH signaling pathway, Prostate cancer
MW 38.4 kDa
Gene Summary This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations