Thap1 (BC038639) Mouse Untagged Clone
CAT#: MC206569
Thap1 (untagged) - Mouse THAP domain containing, apoptosis associated protein 1 (cDNA clone MGC:47985 IMAGE:5118383), (10ug)
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Thap1 |
Synonyms | 4833431A01Rik; AW490810 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC038639
GCCATCTTGAAGATGGGAGACGGGCGACAGCTGTGGTCCTTCTGCTAAAGCAAACCCCACAACGGACAGG GTAGTCACTCCCCCACCCCAACCCCCACCCCACGGCGAGGTGATCGTCCCCGTAACTGCTGACCGACGCC ACCGAGAGCGGCGAGCGTTATCAAGGCCGAGCGCGGCGACCCCGACGGCCCCCTTCGCCTGCCTCCCGGG CCGAAGGGAAGTGTGGAGGGCCAGAAGGATGGTGCAGTCCTGCTCCGCCTACGGCTGCAAGAACCGCTAC GACAAGGACAAGCCCGTCTCCTTCCACAAGTTTCCTCTTACTCGCCCCAGCCTTTGTAAGCAGTGGGAGG CAGCTGTTAAAAGGAAAAACTTCAAGCCCACCAAGTACAGCAGCATCTGCTCGGAGCACTTCACCCCGGA CTGCTTTAAGAGGGAGTGCAACAACAAGCTACTGAAGGAGAACGCTGTGCCCACAATATTTCTCTATATC GAGCCACATGAGAAGAAGGAAGACCTGGAATCCCAAGAACAGCTCCCCTCTCCTTCACCCCCCGCTTCCC AGGTTGATGCTGCTATTGGGCTGCTAATGCCCCCTCTGCAGACCCCTGATAACCTGTCGGTTTTCTGTGA CCACAATTACACTGTGGAGGATACGATGCACCAGAGGAAGAGGATCCTGCAGCTGGAGCAGCAGGTGGAG AAACTCAGGAAGAAGCTCAAGACGGCCCAGCAGCGGTGCCGGCGGCAGGAGAGGCAGCTCGAGAAGCTCA AGGAAGTCGTCCACTTTCAGAGAGAGAAGGACGACGCGTCCGAGAGGGGCTACGTGATCCTACCAAATGA CTACTTTGAAATTGTTGAAGTTCCAGCATGAAAAAATGAGATGTGTTAGTGGGACAAGACTATACACCTT CTTTTAGCCTACATACAGGAGTTCATTTGAAAAAATAACACTTAATTACTTGTATTAAAAAAACAATATT TTTTTAAAATAAATTAGATATATACTGTAAAAAAAAAAAAAAAAAAA |
Restriction Sites | EcoRI-NotI |
ACCN | BC038639 |
Insert Size | 633 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | BC038639, AAH38639 |
RefSeq Size | 1027 bp |
RefSeq ORF | 633 bp |
Locus ID | 73754 |
Cytogenetics | 8 A2 |
Gene Summary | DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis (By similarity).[UniProtKB/Swiss-Prot Function] |
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