Ivns1abp (BC004092) Mouse Untagged Clone

CAT#: MC206466

Ivns1abp (untagged) - Mouse influenza virus NS1A binding protein (cDNA clone MGC:8306 IMAGE:3593827), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ivns1abp
• Synonyms: Nd1-L, Nd1-S, 1700126I16Rik, 1190004M08Rik, ND1, NS-1, NS1-BP, HSPC068
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004092
  CTTTTAAGGACTTGATTACATCATTTTCAAGCCTGCTAGTTTTGGAACCACCATTAAAGCCTAAGACATC TCCCTTCAGTCAGCCACCTTTCTTCACACTGTAACGAAGTGCTTTGTTTCAACACTCCTTCTTTGTCTTT GGATCATTTGCGTTCTCAGTGACACATTTCTCTTCAGTAATTGTTGCCAAATTTATAAGGAAAAATGATT CCCAATGGATATTTGATGTTTGAAGATGAAAATTTTATTGAATCATCTGTTGCCAAATTAAATGCCTTGA GGAAGAGTGGGCAGTTCTGTGATGTTCGACTTCAGGTCTGTGGCCATGAGATGCTAGCACACAGGGCAGT CCTGGCTTGCTGTAGCCCCTATCTATTTGAAATCTTCAATAGTGACAGTGACCCTCATGGAGTTTCTCAT GTGAAGTTGGATGATCTCAATCCAGAAGCTGTTGAAGTCTTGCTGAATTATGCATACACGGCTCAGTTGA AAGCTGATAAGGAATTAGTAAAAGATGTTTATTCTGCAGCCAAGAAGCTGAAGATGGACCGAGTCAAGCA GGTCTGCGGAGATTATTTACTATCTAGAATGGATGTTACTAGCTGCATCTCTTACCGAAATTTTGCAAGT TGTATGGGAGACTCCCGTTTGTTGAATAAAGTTGACGCTTATATTCAGGAGCATTTGTTACAAATTTCAG AAGAGGAGGAATTTCTTAAGCTTCCGAGACTAAAGTTGGAGGTAATGCTTGAAGATAATGTGTGCTTGCC CAGCAATGGCAAGTTGTATACAAAGGTAATCAACTGGGTGCAGCGTAGCATCTGGGAGAATGGAGACAGC CTGGAGGAGCTCATGGAAGAGGTTCAAACCTTGTACTACTCAGCTGATCACAAGCTGCTTGATGGGAACC CACTAGATGGACAGGCTGAGGTGTTTGGCAGTGATGATGACCACATTCAGTTTGTGCAGAAAAAGCCACC CCGTGAGAATGGCCATAAGCAGATAAGTGGCAGTTCCACTGGATGTCTCTCTTCTCCAAATGCTTCAATG CAAAGCCCTAAGCATGAGTGGAAAATCGTTGCTTCAGAAAAGACTTCAAATAACACTTACTTGTGCCTGG CTGTGCTGGACAGTACATTCTGTGTCATTTTCCTTCATGGGCGGAACAGTCCACAGAGCTCACCAACAAG TACTCCAAAACTGAGCAAGAGTTTAAGCTTCGAGATGCAACCAGATGAGCTTCTAGAAAAGCCCATGTCT CCCATGCAGTACGCACGGTCTGGACTAGGGACAGCAGAGATGAATGGCAAACTCATAGCTGCAGGTGGTT ATAACAGAGAGGAATGTCTTCGAACAGTTGAATGCTATGATCCACATACAGATCACTGGTCCTTCCTTGC TCCCATGAGAACACCAAGAGCCCGCTTTCAAATGGCTGTGCTGATGGGACAGCTCTATGTGGTGGGTGGA TCAAATGGACACTCAGATGACCTGAGTTGTGGAGAAATGTATGATCCAAACATTGATGACTGGACCCCTG TTCCAGAGCTGAGAACCAACCGTTGTAATGCAGGAGTGTGTGCTCTGAATGGGAAATTGTACATTGTTGG TGGCTCTGATCCATATGGTCAAAAGGGCCTGAAAAATTGTGATGTATTTGATCCTGTAACGAAGTCATGG ACAAGCTGTGCTCCTCTTAACATTCGTCGACACCAGTCTGCAGTTTGTGAACTTGGTGGTTATTTGTATA TAATTGGAGGTGCAGAATCTTGGAATTGTCTGAACACAGTAGAACGATACAATCCTGAAAACAACACCTG GACTTTAATTGCATCCATGAATGTGGCGAGGCGAGGGGCTGGAGTCGCTGTGCTTGATGGAAAACTGTTT GTAGGTGGTGGCTTTGATGGTTCTCACGCCATCAGTTGTGTGGAGATGTATGATCCAACTAGAAATGAAT GGAAGATGATGGGAAATATGACTTCACCAAGGAGCAATGCTGGGATCACAACTGTAGGGAATACCATTTA TGCAGTGGGAGGATTCGATGGCAATGAGTTTCTGAATACTGTGGAAGTCTACAACCCTCAGTCAAATGAG TGGAGCCCTTACACAAAGATTTTCCAGTTTTAACAAATTTAAGAACCCCAAACTAACAGGCTTAGTGATG TAATTGTGTTTAGTAGAGGTACACTTGTGAATAAGGAGGGTGGGTGGGGTAGATGTTGCTAACTGCAACA CAAAGCTTTTGCATATTGCATATTATTAAACATGCTGTACATACTTTTTGTGTTTGGAACGGAATGCAAA GATGAAGGTCTGTTTCTGTATTCTTAAGACATCTTTGGTTATTTTACTTTTTGAAGGTTGATACTGTAAA AGAATAAACCACAAATTGATTGGGAACATCATTTCAAGAAGTCCCTGCTCCTCCACATTTGTTTTGCCGA TTTGCACATTAAATGACTCTTCCCTCAATTCTGTCTTAAGAGGCAAGAGGGGTAGGGTTTACACGTAGGC AGTTGGGTTTTTTAAGGGCCCCTTTTCAATAACTGGAACACTCTATAACAAGATACTTATTTAAATAGAT AACAATGACTATTTTTGTTTTTATTAAAAGAAAGTTGACATGCCTACCAATATTTAGTCTTTTATGATTA CATTTTTATAACTTTTTATATTCTCAGCAGAGTGCTTTATCTGTTGAAGTAAAATGTGACAGATTCACAT TATCAAAGCAGAGTGGCAGAGGAAAGGATGCAGAGTGGCTGTTTCTTTTAAAAAATGCTCAGAACTCATT TGCCGCAGCTGTACCTTTTTTTCTTTCCTATCTGAGAGTGCAGTATCGATGTTATTTGGATGGAGTTGCT GAATGGTAACAGTAATTCAAACCCAGGTTTGATGAGTTACTTGACTTACTGAAGCATTTAAACTGTCTTT ATTTATCATTAACCAAACAAATGTAAGTGGAAGCCTTTGATTGAAAACAATTAAACTGTATTGGGTTTGT GAATGCAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: EcoRI-NotI
• ACCN: BC004092
• Insert Size: 1929 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004092, AAH04092
• RefSeq Size: 3036 bp
• RefSeq ORF: 1929 bp
• Locus ID: 117198
• Cytogenetics: 1 G1
• Gene Summary: Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (PubMed:12213805, PubMed:16317045). Protects cells from cell death induced by actin destabilization (PubMed:16952015). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (By similarity). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (By similarity). Inhibits pre-mRNA splicing (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function]