Usp11 (NM_145628) Mouse Untagged Clone

CAT#: MC205643

Usp11 (untagged) - Mouse ubiquitin specific peptidase 11 (Usp11), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Usp11
• Synonyms: 6230415D12Rik; mKIAA4085
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC005470
  CAGCCACCTATTGAGCGCAAGGTAATAGAACTTCCTGGCATTCGGAAGGTGGAAGTGTACCCACTAGAGC TACTGCTCGTTCAGCACAGTGATATGGAAACAGCTCTCACCATTCAGTTTAGCTATACTGATTCTGTGGA ACTAGTCTTGCAAACAGCTCGGGAGCAGTTTCTGGTAGAGCCTCAGGAAGACACGCGCCTCTGGACCAAG AACTCAGAGGGCTCTTTGGATCGACTGTGTAATACACAGATCACGCTGCTTGATGCCTGCCTTGAGACTG GGCAGTTGGTCATCATGGAGACTCGAAACAAAGATGGCACTTGGCCCAGTGCTCAGCTGTGTGGCATGAA CAACATACCGGACGAGGATGAGGACTTCCAGGGGCAACCGGGCATCTGTGGCCTTACCAATCTGGGCAAC ACATGCTTCATGAACTCGGCCCTACAGTGCCTGAGCAATGTGCCACAGCTGACAGAGTACTTTCTCAACA ATCGCTACCTAGAGGAGCTCAACTTCCGGAACCCTCTAGGCATGAAGGGTGAGCTTGCTGAGGCCTATGC AGATCTGGTAAAGCAGACTTGGTCTGGCTACCACCGCTCCATTGTGCCAAATGTGTTCAAGAACAAGGTT GGCCATTTTGCATCCCAGTTTCTGGGCTACCAGCAGCATGACTCACAGGAACTACTGTCATTCCTCCTGG ATGGGCTACATGAGGATCTCAATCGGGTCAAAAAGAAAGAATATGTTGAGCTATGCAATGGTGCTGGGCG GCCTGATCTGGAAGTGGCTCAGGAAGCCTGGCAGAACCATAAACGACGAAATGATTCTGTGATCGTGGAC ACTTTCCATGGCCTCTTCAAGTCCACCCTGGTGTGCCCTGATTGTGGCAATGTTTCTGTGACCTTTGACC CCTTCTGCTACCTCAGTGTCCCACTGCCTGTCTGCTCCAGGAGGGTCTTGGAAGTCTTCTTTGTCCCCAT GGATCCCCGCCGCAAGCCAGAACAGCACCGGGTTGTAGTCCCCAAGAAGGGCAATATCTCAGATCTGTGT GTGGCTCTGTCCACGCATACAAGTGTTGCACCAGACAAGATGATAGTAGCTGATGTCTTCAGTCACCGAT TCTATAAGCTTTACCAGCTGGAGGATCCTCTGAGTGGCATCTTGGATCGTGATGATATCTTTGTATATGA GGTGACTGGTCGGATTGAGCCGGTTGAGGGTTCAAGAGATGATATTGTGGTACCTGTTTACTTGCGGGAG CGCACCCCATCCAGAGACTACAACAACTCCTACTATGGTCTGATACTTTTTGGGCACCCTCTCCTGGTGT CAGTGCCCCGGGACCGGTTCTCCTGGGAGGGCCTATATAACATCTTGATGTACCGACTTTCACGATATGT GACCAAACCCACCTCAGATGAGGATGATGGGGATGAGAAAGTTGATGAAGATGAGGATGAGGATGTGGAA GATGACAGCAGCAGTGAGGAGGAAAAGGAGGAAATGTCTGCGCCCACTGTTAATGATGGGACCCGAGAAG CAGAGCAGGAGCAGGCTGGGACCAGCTCTGGGGTCACTGAGAGATGCCCATCCCTCTTAGACAACAGCCT CCGCGCATCGCAGTGGCCCCCAAGGCGACGACGAAAGCAGCTGTTTACTCTGCAGACGGTGAACTCCAAT GGAACCAGTGACCGGACCACTTCCCCTGAAGAAATGCAAACCCAGCCATACATTGCCATGGATTGGGAAC CAGATATGAAGAGGCGTTATTATGACGAAGTGGAGGCTGAGGGCTATGTGAAGCATGACTGTGTGGGCTA CATGCTGAAGAAAAGTCCAGTGCAGCTGAAGGAGTGCATCAAACTCTTCACCACTGTGGAAACCCTGGAG AAGGAGAACCCCTGGTACTGCTCCTCCTGCAAGCAGCACCAGCTGGCCACCAAGAAACTGGACCTCTGGA TGCTACCCGAAGTTCTCATTATCCACCTGAAGCGTTTTTCATTTTCCAAAATTTCCCGGGAGAAGCTGGA CACCCTGGTGCAGTTTCCTATCCGGGACCTGGATTTCTCTGAGTTTGTCATCAAACCAAAGAATGAGTCT TCTCCAGACCTCTACAAATATGATCTCATCGCAGTTTCCAACCATTATGGTGGCATGCGTGATGGACACT ATACAACATTTGCCTGCAACAAGGACAGTGGCCAGTGGCACTACCTTGATGACAATAGTGTCTCACCTGT GAATGAGAATCAGATTGAGTCCAAGGCAGCCTATGTCTTGTTCTATCAGCGCCAAGATGTGGGTCGACGC CAGTCCCAGACTTCTTCATCTGACACTCCTGCCTCTCCTGTCTCCAGTTCTACACCCAACTCTGACATCA TGGATATCAACTAAGGAGCCCTAGAACCTACCATGGAGAAGGAAGCCCCCTTTGCCACTCTCTCCTGTCT ACCCCCTCTCTTTCCTGTGTTTATCGCCCCCCTCTGCCCCCCCAGACATTGCAGGCTTAGTCTGTGGCTA CTGTTCTCTTGTACCGCTGTATTACTCTCTCAGAAAGAAGAGGCCCTATGCCCCTGGCAGTGTGCCCCTG CCTGTGTGTGCCCGTACAGCAGTGACTTCCTCTCCTAGTCTTATTTATGCTCCCCCTCCCTCTTTTCCTC ATGCCAAAGTGTTCTTAGTGGCTGATACTGGGGTTTACATGAACACAGAGTGTATTTTCTTATTGAGACC ATACCTTCTTCTCTGTGTTAAGTATCCATAAAAAGCTCCAGATTCCCATGTTCAACAGTGTGGCTTTGTT TCTTCATATGTACTTACTATGTACCAGTCATATGTCTTTGTTCAGTTGACTTACTGAAGGTCAAGTATGG TATGTAGTTGATGCTGTCCTGAGTGGGTTTGTTGTTTTTGAGACAGGATCTGTCTGTGTAGCTCTTGGGT GTCCTGGAACTCACTGTGTGGATCAGGCTGGCCTTTAACTCAGAGATTGTACCTCTGCCTCCTAAGTGCT GGCATTAAAAGCATGACCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_145628
• Insert Size: 2100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC005470, AAH05470
• RefSeq Size: 3086 bp
• RefSeq ORF: 2100 bp
• Locus ID: 236733
• UniProt ID: Q99K46
• Cytogenetics: X A1.3
• Gene Summary: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro). Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex; may act by deubiquitinating components of the PRC1-like complex.[UniProtKB/Swiss-Prot Function]