Gna13 (NM_010303) Mouse Untagged Clone

CAT#: MC205559

Gna13 (untagged) - Mouse guanine nucleotide binding protein, alpha 13 (Gna13), (10ug)


  "NM_010303" in other vectors (4)

Reconstitution Protocol

USD 457.00

In Stock*

Size
    • 10 ug

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Frequently bought together (3)
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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Gna13
Synonyms AU024132; AU043124; Galpha13
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC057665
CGCAGGGGCCCGCCGAGGCGGCGGCGGCGGCAAGATGGCGGACTTCCTGCCGTCGCGCTCCGTGCTGTCC GTGTGCTTCCCGGGCTGCGTGCTGACGAACGGCGAGGCCGAGCAGCAGCGCAAGTCCAAGGAGATCGACA AATGCCTGTCGCGGGAGAAGACCTACGTGAAGCGGCTGGTGAAGATCCCGCTGCTGGGCGCGGGCGAGAG CGGCAAGTCCACCTTCCTGAAGCAGATGCGGATCATCCACGGCCAGGACTTCGACCAGCGCGCGCGCGAG GAGTTCCGCCCCACCATCTACAGCAACGTGATCAAAGGTATGAGGGTGCTGGTAGATGCCCGAGAGAAGC TTCATATTCCCTGGGGAGATAACAAAAACCAGCTCCATGGAGACAAGTTGATGGCATTTGATACCCGCGC CCCCATGGCTGCCCAGGGGATGGTGGAGACTCGAGTGTTCCTGCAGTATCTTCCTGCTATCAGAGCCTTA TGGGAGGACAGTGGTATACAGAATGCCTACGATCGGCGCCGGGAATTCCAGCTGGGTGAGTCTGTAAAGT ATTTCTTGGATAACTTGGATAAACTTGGAGTACCGGATTACATTCCATCACAGCAAGATATCCTGCTTGC CAGAAGGCCCACCAAAGGCATCCATGAGTACGACTTTGAAATTAAAAATGTTCCTTTCAAAATGGTTGAT GTAGGTGGCCAGAGATCAGAACGGAAACGCTGGTTTGAATGCTTTGACAGTGTGACGTCGATACTTTTCC TTGTCTCTTCAAGTGAATTTGACCAGGTGCTTATGGAGGACCGCCAGACCAATCGCCTTACAGAATCTCT GAACATTTTTGAAACAATTGTCAACAATCGGGTTTTCAGCAACGTCTCCATAATCCTCTTCTTAAACAAG ACAGACTTGCTCGAGGAGAAAGTGCAAGTTGTTAGCATCAAAGACTATTTCCTAGAATTTGAAGGGGACC CCCACTGCTTAAGAGACGTCCAAAAGTTTCTGGTGGAATGCTTCCGGGGGAAACGCCGGGACCAGCAGCA GAGGCCGTTGTACCACCACTTCACCACCGCGATCAACACAGAGAACATCCGCCTCGTGTTCCGGGACGTG AAGGACACGATCCTTCATGACAACCTGAAGCAGCTCATGCTGCAGTGATGACAAGACTGGCTGTTTTAAT ACCTTGTTGTGATTTTGATTGTTTTCTGTTTGTCTTGTTTTTCTCTTTAAATGGCAGTTTACAACAGCAG TTAGAAGAATCTCAGTTGTGTGTGTCTAACTTCTTGGAGAACTTAGTTCATCTGTGGCCTTTAGTTTGTG GCTGACAGCTGCTGAATTAACCCATTGCCAATATCTGCTAGAATTTGGGCTTTGATTGGTTTCACTGTGG CTTACCTTCAAGTCCAATTATAACTTCCTGGCAACCTTACACTAGGTGTTTTTCAGGCCTTGAATTCTCA TAACTGTCCTGCAGTTCTAAGAATAGGCAGTATCTTTAAGAACTTGTAGGGATGAGAGTATGAAAATTCA GCTCTAAAGAGAGAGTGCCTTACCCAGCAATGACATGCCTCGCTATGTGAGCCCTGGTCTGGAAGGGCTG TTAGAGAAAAGTTTTAGGGAGGAGTCTCGGCCCACAGAGGCTTGGCCCCCTACACACACAGCAGTAGTTT GTTTTTCTCAATCTCTTTACTTTCTGAAGGTAATGTCTTACTGCTTAAGTTTACAAGATGGATCTCAGCC TGATGCTGATGCGGTCACAAATGGTACATGTGCTATGTTGATCTGAGATGAGCAGTGACACGCAGTTTCC TTTGCCATACATGCTGTCACTAACTTAATGTGCCATGTTACAACATCTGGAGAGGGCAAGCACCCTGGTG ACGGACATCACCATAGCAGCCCCAGAGTGTGACTTTCTGGTCCTGTCTCCTTGGACTTTGTGCCTTGCTG GAGGGAACCACTGTTGGGTCTTCTTCCTTTTGCCCCACTGTCTCAACCTCAGCAGCTCTGAACTGTGGTG CTCTCGGGCTTCTCTTGTCCCCGAGAGCTTGGTGGGCAGCATTTCCCTGTGAACTGTTCAAAAAGGCATC CTTTCAGTACCCTGTCCCTGGTTAGTGTCTCTCTGTGACAGAGTTTGTATGTGTTGTGTGTGTCATCGTG TGTGAGACACAGCTTCATTGAGGTACATTCAAATGTCTTAAGGATGCATCTAAGGATAAGCAATTTTTTT TTTGGCCCATACTTAAGGAGGTTTGCCTTCACACACACACACACACACACACACACATACCATTGCTAAC TTAAACCATGCCCATGAGGTAGCTTGTGATAAAATACAGTGGCTGGTGTACAAAACCATTTGGCATGTTC CAACTGGCCTGGGAGTTTGTAGAACCTGAGCTTGTCCCTGCTGTCCCTGGAGAGCGCAAGAGGGCAGTGA AGCCTGTTTTATTGTGTGACTATTCTCAGGCAAGAAATTGCGCCCTGAAAGACTGGCTGACTATGAGGCC CAAAAGCAGTGGCTTTCTTCTTTTCTTGCTGGAGGGTGCCAGAGCTGGGCCCTAGTGTATGTATACTTGA GAGACCTGACTTGTCCTGGATTTGAGCTTTCACTGTCATTCTGGTTATAAAGTCCAGTGCTTTCTTGCCT TGGTAATATCATGAGCTTAAGACATGTATGTCAGTATCACAGTGCAGGTGTTGTTAGCATAATTCACCAT AATTCATGGTTCTACATCTGGTCCTTTTTCTGTCAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN NM_010303
Insert Size 1134 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq BC057665, AAH57665
RefSeq Size 2779 bp
RefSeq ORF 1134 bp
Locus ID 14674
UniProt ID P27601
Cytogenetics 11 71.88 cM
Gene Summary Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:21212405, PubMed:19151758, PubMed:16388592). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:16388592). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (PubMed:19151758, PubMed:21212405). Promotes tumor cell invasion and metastasis by activating Rho/ROCK signaling pathway (By similarity). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (By similarity).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant 1 represents the longer transcript and encodes the longer isoform (1).

Other Versions

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