Mbtps2 (NM_172307) Mouse Untagged Clone

CAT#: MC204537

Mbtps2 (untagged) - Mouse membrane-bound transcription factor peptidase, site 2 (Mbtps2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mbtps2
• Synonyms: 9630032G22Rik; AI662535
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC038343
  CCGGGCGGGCGCACGGCTGACTGGGGCTCGCAGAAGCAGGCCGCCGGGGCCCGCCGTCCATCCGTCGCTA CGATGATTCCGGTGTCGCTGCTGGTGGTGGTGGTGGGTGGTTGGACTGCCGTCTACCTGGCCGACTTGGT GTTGAAGTCATCTGTGTATTTTAAACATTCTTATGAAGACTGGCTGGAAAACAATGGATTGAGCATCTCT CCTTTTCATATAAGATGGCAAACTTCAATTTTTAATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAA GGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTGATTGCCATGTTCAGCTCTTTTTTTCT CCTTGGAAAAACACTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTCCTTATTCTTCCTCT TCCTCTTCCTCCTCTTCCTCTTCCTCCTCTTCCTCTTCCTCCTCCTCTCTTCACAATGAACAGGTGTTGC AAGTTGTGGTTCCCGGTATAAATTTACCTGTCAATCAGCTGACTTACTTCTTCGCTGCAGTCCTCATTAG TGGTGTTGTACATGAAATTGGACACGGTATAGCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGA ATTTTTCTCTTCATTATTTATCCTGGGGCATTTGTTGATCTGTTCACCACCCATTTGCAACTTATATCAC CAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATATGGCATAATTTTGTCCTTGCTCTCCTTGGTATTTT AGCTCTTGTTCTCCTCCCAGTAATCCTCTTGCCTTTTTACTACACTGGAGTTGGGGTACTTATCACTGAA GTCGCAGAGGACTCACCTGCCATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACTCATCTACAGG ATTGTCCCGTTACTAATGTGCAAGATTGGAATGAATGTTTAGACACCATTGCATATGAGCCCCAAATTGG GTATTGTATAAGTGCATCAACGTTACAACAATTAAGCTTCCCAGTTAGAGCATACAAACGACTAGATGGT TCTACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTCAATAAAC GTTTGCATACGTGTCTACCTGCCCGGAAAGCAGTTGAAGCTACTCAAGTTTGTAGAAGCAATAAAGATTG CAAAAGCGGCGCAAGTTCTAGCTTCTGTATAGTACCGTCCTTGGAAACTCACACCCGACTAATCAAAGTG AAACATCCCCCGCAAATTGATATGCTGTATGTAGGGCACCCACTGCATCTTCACTACACAGTGAGCATTA CAAGTTTCATCCCACGTTTCAACTTTCTAAGCATAGATCTGCCAGTGATTGTGGAGACATTTGTCAAGTA CCTGATTTCTCTTTCTGGAGCTCTGGCTATTGTTAATGCAGTGCCCTGCTTTGCCTTGGATGGTCAATGG ATTTTAAACTCTTTCCTGGATGCTACCCTTACTTCAGTAATTGGAGACAATGATGTCAAAGATCTGATTG GATTTTTCATCTTGCTTGGTGGCAGTGTACTTTTGGCTGCCAATGTGACACTGGGACTCTGGATGGTTAC AGCACGGTAATGTTTGCTCTCATCCAACAGAATTAAGAAGTAAAGCTACATGGCAATATCTGTTGCCATT GAAATTCTTACTAGTTATGAAATGTAAAGTGTTTCCTTAAAACACCTTGGCCAACCTCTTTGAGCTCCTA ATATCTAGAGAACCCAAAAACTCTGTAGTAGAGGGAGTAGAAGAAATGAAAAGCATAATTCCTGACTATA TCCTACTTTAAAGATTGAATGTGCAAACTCTGAATGTTTGTTGAATAATTTGTAAACAAGTGAAAATTCA TTCATGTAATACCATTTTGTGTGACCATATAGCATTTTGGAATAGTAAAAGGAAAAGCAGAATCTTGTAG GAAAACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGA GAATGCGTGTGTATGTGGTATGTGTCTGCGTGTTCTACTAGTGTTTGAAAGCAGGGCCTTACTTATGCTA CTTAGGCTAAGCTTGCCTGTCCCAGGTAAAAGTTACTGAAAAGTGCCATTAAGGTGATGTGCTGGTGCAC ACCTATAATCCCAGCACCTACCTCTATGTGTTTGGAGGGCTAGGCATAAGGATCGTGAATTCAAGGCCAT CATCTTTAGCTACATAGTAGGTTCCAGACCAGCACTGGCCACATAGCAAGACCCTTTCGTGCATGCATAC ATGCACAGGCGCGCACACACACGCACCCACCCACCCACACACACACACACACACACACACACACACGCAC ATACACAAAATCATTAATGATTGGAAGGAAGCTAGACCTTGGTTGAATGGAAAGTAGAGCAAGTGCTCTT GGTTTTATAACTCTTGTCTTTATCTTATTTGAAAAGTATTTTAAAGTTTAATGGTGTATTATTCTGTACT CTGGTTACAATTCTATGAAAGTATCTGCTAACATGAAAGCAAAAACTCTGTACAAGTGCTATCAAGTAAA TGAGCAATGTTGAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_172307
• Insert Size: 1548 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC038343, AAH38343
• RefSeq Size: 2664 bp
• RefSeq ORF: 1548 bp
• Locus ID: 270669
• UniProt ID: Q8CHX6
• Cytogenetics: X F4
• Gene Summary: Involved in regulated intramembrane proteolysis (RIP) that is the cleavage of membrane-spanning regulatory proteins by proteases within the plane of the membrane. It cleaves sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal fragments shuttle to the nucleus and activate gene transcription. Involved in RIP-mediated regulation of bone formation.[UniProtKB/Swiss-Prot Function]