Dr1 (NM_026106) Mouse Untagged Clone

CAT#: MC203826

Dr1 (untagged) - Mouse down-regulator of transcription 1 (Dr1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dr1
• Synonyms: 1700121L09Rik; Dr1l; NC2; NC2beta
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC013461
  CGCAGGGTGGTTCTCCAGCCCTGGGAGTGGTGTCCCTAGAACCCTCAGCCCCCTGACCTTTCCTTCATAT TCCCACTAAAATCTCTCACACAGTGGGTGTTCCCTGCCCTCCAGCCCTCCTTCCTGGTTTCTGCACTCTC TTCTCTGAGCTTCCCGGACCCCAACATCCCTCTCCAGGGACAGCCTGTTGAGAAATCTTCGTGGAGTGGT GGACCAGAGGCGAGGAGTTTAAAAGTTGGGGCTTGAAAGACAGGAAGATACGATGGCTTCCTCGTCTGGC AACGACGATGATCTCACTATCCCCAGAGCTGCTATAAATAAGATGATCAAAGAGACTCTTCCTAATGTCC GGGTGGCCAACGATGCCCGAGAGCTGGTAGTGAACTGCTGCACGGAATTCATTCACCTTATATCTTCTGA AGCCAACGAGATTTGTAACAAGTCAGAAAAGAAGACAATTTCACCAGAGCATGTTATACAAGCACTGGAA AGTTTGGGCTTTGGCTCTTACATCAGTGAAGTAAAAGAAGTCTTACAAGAATGCAAGACAGTAGCATTAA AAAGAAGAAAGGCCAGTTCTCGTTTGGAAAACCTCGGCATTCCTGAAGAGGAATTATTGAGACAGCAACA GGAATTATTTGCAAAAGCTAGACAGCAACAAGCAGAATTGGCCCAACAGGAATGGCTTCAAATGCAGCAA GCAGCTCAACAAGCCCAGCTGGCTGCAGCCTCAGCCAGCGCGTCCACTCAAGCAGGATCTTCACAAGACG AAGAAGATGATGATGACATCTGACATTCACCACCTGGGCTTTCAAGAAAACAGTGAAAGATATGCCTATC TGTAATTCTGTATGCATCTTGGTGGACTTACCATTGGTATTCTAGAGACGTCTGTTGTCTGGTTTCAACT ACTGTGCTATACATGTAAAACTGTCTCTTTGAACTATTGAAAATTTAAGGTTAAGTATAATATCACCTTT GGATTTGTAATGGTGTTTCTGGAATCTTAGACCAGTGTGAACCCTTTATTTGGTCAATAAACAGTGTTAC AGAAAACTTCAGGTTTATAAAATACAGTGAAATTTATAGAGATCTCTTAATCTGTATTTGTATTTTGTCT GCCCTTTGAACTGAACTAAAATTGAGAATTTATATAGCGATGGGGCATGATGTGATGCAGAATACATTGA ATCAGGTTGGTGAAAAAGTTCAGTTCTATATAGTATCTAAATTTTTTGTCTTTTAAGGTGAGTATATATG CAGGCAACAATTATATATGCTCAGATAAATATACTTGTTTAGAGGAAATCTCAAATAAGACATTCAATAA CTAGGAAAGAAATGTACTCACTAGTAGTTGTATAAATTTGGTGAGTTATATTTTTGATTTTGTTACTGTT TTGTGTAACAGTGAAGACTGGTTTTATTATAGTATAATTTATCTTGAACTACACTATGCCATTTCAGAGA CTGGCTAATCTTGAAGATTGTCACAATTCTTACTGTTTCACTCCAGTTCAGTAATTGTTCATAGTCTTAG TTGTTTCGTCCATTTTTTGAGTGTATAGGTGGGACTTGTGAGACAGTTGCTTGGGTTCTGTTAGTTTAAC TGAGGTTGCTGGATATTCAAACCTTTGCTAGGGGAAATAAACGAAAGCTAATGAACATGTTTGCTATGAA AAAGGGCTTTAAATTTTTATTTAACATGTAGTGTACTTATTGTTTGGTTTTAGTGTAGCATTTACATTTT CTCGACTAGGTGGCCTAAAGAATCCAATGCTAACTTTTGATAATAACATCATTGTCCCCGTCATCATAAT TTAGTAGTAGCTTTAAAAGTTTTGTGTTTGCTTAAAAAGTGTCATAACTGCAGCCCTATATGAAGTGTTA ACTTGCTTGTTAAAAGGAAGCAGCTTTAATTTGGTTCCAGTGCATAAAGTGTGGTAGTGTTTGTGAGAGG GATCCAGTGTATTTGGTGAAATGGCATATTACTTATATTTTGGAAACAAAAAAATGCCACCTAAGATAAT AATATAAGTCATTAAGTTCCTATGTCAGTTGCCAAGCCATTTAAATTTCTGTATTCACCAAGCCCCAGAA GAGATTCTAGCTGCTAGGATTTGAATTTTGAAAGCTAAGAAATGTTTATAAGTATTAGATTTCTTAATAT TCATATTTTTGAGTTTTAGAAGGGAAATTTATATGCATATTGTTATGCATTTATCAGATATTCTTCCCCC ATATAACAAAAAGGGTAGTAATTTTGCTGAATGTTTTATGTTGAAGTTATTTCAAGGTATTTCATGGATA TGCCCATGACATATTTGGAAAAAATAGAAGGAATTGATTTTTTCAAAAAGGTTAAGTACCAAAGGTAGGT AGTTTAGTCTACAGAAATAAGTTAGTCACTTTTGGCTTTTCTAATTTGTACTGTAACATTCTTTTATTTT GTTTTAAATATATGTTTCTCAAGTAAACAATTTAGGTAATTTTCCATACCTTTTTCTTTCTGATGCAGAC TTCAGGTTAATTAATATTTTACTGCATCTGATGATGTATTATATGTTTGAAGCCTAGTGACTTTTAATTT TGATGTTCTTGTGATTTCATATGTTGTATTCTTCAAGCAATAAAATTCTGATGTGTTTTATAAAAAAAAA AAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_026106
• Insert Size: 531 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC013461, AAH13461
• RefSeq Size: 2666 bp
• RefSeq ORF: 531 bp
• Locus ID: 13486
• UniProt ID: Q91WV0
• Cytogenetics: 5 52.82 cM
• Gene Summary: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).[UniProtKB/Swiss-Prot Function]