Ctsk (NM_007802) Mouse Untagged Clone

CAT#: MC203096

Ctsk (untagged) - Mouse cathepsin K (Ctsk), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ctsk
• Synonyms: AI323530; cat; catK; MMS10-Q; Ms10q
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC046320
  ATCTAGCACCCTTAGTCTTCCGCTCACAGTAGCCACGCTTCCTATCCGAAAAGAGCCTAGCGAACAGATT CTCAACAGCAGGATGTGGGTGTTCAAGTTTCTGCTGCTACCCATGGTGAGCTTTGCTCTGTCTCCGGAGG AAATGCTGGACACCCAGTGGGAGCTATGGAAGAAGACTCACCAGAAGCAGTATAACAGCAAGGTGGATGA AATCTCTCGGCGTTTAATTTGGGAGAAAAACCTGAAGCAAATCTCTGCCCATAACCTGGAGGCCTCTCTT GGTGTCCATACATATGAACTGGCCATGAACCACTTGGGAGACATGACCAGTGAAGAAGTGGTTCAGAAGA TGACGGGACTCAGAATACCTCCCTCTCGATCCTACAGTAATGACACTCTCTATACCCCAGAGTGGGAAGG CAGGGTCCCAGACTCCATCGACTATCGAAAGAAAGGATACGTTACTCCAGTCAAGAACCAGGGCCAGTGT GGTTCCTGTTGGGCTTTCAGCTCTGCCGGGGCCCTGGAGGGCCAACTCAAGAAGAAAACTGGTAAACTCT TAGCTCTGAGTCCCCAGAATCTTGTGGACTGTGTGACTGAGAATTATGGCTGTGGAGGCGGCTATATGAC CACTGCCTTCCAATACGTGCAGCAGAACGGAGGCATTGACTCTGAAGATGCTTACCCATATGTGGGCCAG GATGAAAGTTGTATGTATAACGCCACGGCAAAGGCAGCTAAATGCAGAGGGTACAGAGAGATTCCTGTGG GGAACGAGAAAGCCCTGAAGAGAGCAGTGGCGCGGGTAGGACCCATCTCTGTGTCCATCGATGCAAGCTT GGCATCTTTCCAGTTTTACAGCAGAGGTGTGTACTATGATGAAAATTGTGACCGTGATAATGTGAACCAT GCAGTGTTGGTGGTGGGCTATGGCACCCAGAAGGGAAGCAAGCACTGGATAATTAAAAACAGCTGGGGAG AGAGCTGGGGAAACAAAGGATATGCTCTCTTGGCTCGGAATAAGAACAACGCCTGCGGCATTACCAACAT GGCCAGCTTCCCCAAGATGTGATTCCAGCCAGCCAGCCCATCTCTTCTCAGATTCCTTCCTTCATGGTGC AAGATATTGGTGGCTTTGGAAGGGAGTGGGCATGGCGCTCCTGAGAGGGACGCAGCGATGCTAACTAAGA TTGTTTCATTTCTCCTCTCGTTGGTGCTTCCAGTGACAACTCTACTTCCCTTCTCTCTGCCCAGGGCCCT TTTCTTTGTGGACACAACAGGGCATTTTTCTGAGAGTTGTGGACTCTGTGCTGGTAGACATTGGAGTCCT CCAGCAGGCTGGAGGACTAAGGTGACCTTCCCGAGCCCCTGTCTTCTGTATACACCAGTGAACATTTCAG TCTTCCACTGAGATGCACAAATCTATTCGTGATTCTTTGACAAATTTACATGATATTAAAAAAAGTGTTT TTCCTTCTTTGTATTTGAAATAAAGTATCTCATTTACAATTTAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_007802
• Insert Size: 990 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC046320, AAH46320
• RefSeq Size: 1562 bp
• RefSeq ORF: 990 bp
• Locus ID: 13038
• UniProt ID: P55097
• Cytogenetics: 3 40.74 cM
• Gene Summary: This gene encodes a member of the cathepsin family of cysteine proteases that is highly expressed in osteoclasts and is involved in the degradation of collagen and other matrix proteins in bone. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme. Mice lacking the encoded protein exhibit phenotypic features of pycnodysostosis such as increased bone density and bone deformity, which become progressively more pronounced with age. [provided by RefSeq, Jan 2016]